1994 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Article

Specific Polyunsaturated Fatty Acids Can Modulate in vitro Human moDC2s and Subsequent Th2 Cytokine Release

Hoppenbrouwers, T., Fogliano, V., Garssen, J., Pellegrini, N., Willemsen, L. E. M. & Wichers, H. J., 4 May 2020, In : Frontiers in Immunology. 11, 748.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Stakeholder and consumer views regarding novel hypoallergenic foods

van Putten, M. C., Gilissen, L. J. W. J., Gremmen, B., Peijnenburg, A. A. C. M., Wichers, H. J. & Frewer, L. J., 2010, In : British Food Journal. 112, 9, p. 949-961

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Structure and Function of Human Tyrosinase and Tyrosinase-Related Proteins

Lai, X., Wichers, H. J., Soler-Lopez, M. & Dijkstra, B. W., 2 Jan 2018, In : Chemistry - A European Journal. 24, 1, p. 47-55

Research output: Contribution to journalArticleAcademicpeer-review

47 Citations (Scopus)

Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis

Lai, X., Wichers, H. J., Soler-Lopez, M. & Dijkstra, B. W., 2017, In : Angewandte Chemie-International Edition. 56, 33, p. 9812-9815

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
45 Citations (Scopus)
37 Citations (Scopus)

Synthesis of the antioxidant hydroxytyrosol using tyrosinase as biocatalyst

Espin, J. C., Soler Rivas, C., Cantos, E., Tomas Barberan, F. A. & Wichers, H. J., 2001, In : Journal of Agricultural and Food Chemistry. 49, 3, p. 1187-1193

Research output: Contribution to journalArticleAcademicpeer-review

107 Citations (Scopus)

Systematic review on cashew nut allergy

van der Valk, J. P. M., Dubois, A. E. J., Wichers, H. J., de Jong, N. W. & van Wijk, R., 2014, In : Allergy. 69, p. 692-698

Research output: Contribution to journalArticleAcademicpeer-review

48 Citations (Scopus)
Open Access
22 Citations (Scopus)

The density of common mushroom (Agaricus bisporus) tissue related to the shrinkage at heating

Schijvens, E. P. H. M., Ruisch, H., van Deelen, W., Biekman, E. S. A. & Wichers, H. J., 1996, In : Mushroom News. 44, 9, p. 14-19

Research output: Contribution to journalArticleProfessional

The effect of endurance exercise on intestinal integrity in well-trained healthy men

Janssen Duijghuijsen, L., Mensink, M., Lenaerts, K., Fiedorowicz, E., van Dartel, D. A. M., Mes, J. J., Luiking, Y. C., Keijer, J., Wichers, H. J., Witkamp, R. F. & van Norren, K., 1 Oct 2016, In : Physiological Reports. 4, 20, e12994.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
14 Citations (Scopus)

The effect of low vs. high temperature dry heating on solubility and digestibility of cow's milk protein

Zenker, H. E., Raupbach, J., Boeren, S., Wichers, H. J. & Hettinga, K. A., Dec 2020, In : Food Hydrocolloids. 109, 106098.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
1 Citation (Scopus)

The Effect of Tomatine on Gene Expression and Cell Monolayer Integrity in Caco-2

Arena, M., Govers, C. C. F. M., Lotti, C., Ricciardi, L., Wichers, H. J. & Mes, J. J., 13 Mar 2018, In : Molecules. 23, 3, 644.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2 Citations (Scopus)

The effects of tolaasin, the toxin produced by Pseudomonas tolaasii on tyrosinase activities and the induction of browning in Agaricus bisporus fruiting bodies

Soler Rivas, C., Arpin, N., Olivier, J. M. & Wichers, H. J., 1999, In : Physiological and Molecular Plant Pathology. 55, 1, p. 21-28

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)

The Impact of Dietary Long-Chain Polyunsaturated Fatty Acids on Respiratory Illness in Infants and Children

Hageman, J. H. J., Hooyenga, P., Diersen-Schade, D. A., Scalabrin, D. M. F., Wichers, H. J. & Birch, E. E., 2012, In : Current Allergy and Asthma Reports. 12, 6, p. 564-573

Research output: Contribution to journalArticleAcademicpeer-review

20 Citations (Scopus)
45 Citations (Scopus)

The Mutual influences of man-made pollutants and allergic manifestations

Jeurink, P. V., Damialis, A., Wichers, H. J. & Savelkoul, H. F. J., 2016, In : APSTRACT: Applied Studies in Agribusiness and Commerce. 10, 2-3, p. 97-106

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The oxidation of 4-hydroxystilbene catalysed by mushroom, pear and grape polyphenol oxidases

Espin, J. C., Soler-Rivas, C. & Wichers, H. J., 2000, In : Recent Advances in Phytochemistry. 1, p. 7-18

Research output: Contribution to journalArticleAcademicpeer-review

The oxidation of L-ascorbic acid catalysed by pear tyrosinase

Espin, J. C., Veltman, R. H. & Wichers, H. J., 2000, In : Physiologia Plantarum. 109, 1, p. 1-6

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Scopus)

The production of podophyllotoxin and its 5-methoxyderivative through bioconversion of cyclodextrin-complexed desoxypodophyllotoxin by plant cell cultures

van Uden, W., Bouma, A. S., Bracht Waker, J. F., Middel, O., Wichers, H. J., de Waard, R., Woerdenbag, H. J., Kellogg, R. M. & Pras, N., 1995, In : Plant Cell, Tissue and Organ Culture: an international journal on in vitro culture of higher plants. 42, 1, p. 73-80

Research output: Contribution to journalArticleAcademicpeer-review

41 Citations (Scopus)

Thermodynamic characterization of the PR-10 allergens Bet v 1, Api g 1 and Dau c 1 and pH-dependence of nApi g 1 and nDau c 1

Bollen, M. A., Wichers, H. J., Helsper, J. P. F. G., Savelkoul, H. F. J. & van Boekel, M. A. J. S., 2010, In : Food Chemistry. 119, 1, p. 241-248

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)

THP-1 cell line: an in vitro cell model for immune-modulation approach : Review

Chanput, W., Mes, J. J. & Wichers, H. J., 2014, In : International Immunopharmacology. 23, 1, p. 37-45

Research output: Contribution to journalArticleAcademicpeer-review

304 Citations (Scopus)

Transcription profiles of LPS-stimulated THP-1 monocytes and macrophages: a tool to study inflammation modulating effects of food-derived compounds

Chanput, W., Mes, J. J., Vreeburg, R. A. M., Savelkoul, H. F. J. & Wichers, H. J., 2010, In : Food & Function. 1, 3, p. 254-261

Research output: Contribution to journalArticleAcademicpeer-review

138 Citations (Scopus)

Tyrosinase isoforms from the fruitbodies of Agaricus bisporus

Wichers, H. J., Gerritsen, Y. A. M. & Chapelon, C. G. J., 1996, In : Phytochemistry. 43, 2, p. 333-337

Research output: Contribution to journalArticleAcademicpeer-review

61 Citations (Scopus)

Voeding en immuniteit: Kan voeding bijdragen aan het voorkomen van allergie, infectie en ontsteking?

van Neerven, R. J. J., Albers, R., Wichers, H. J., Garssen, J. & Savelkoul, H. F. J., Mar 2017, In : Nederlands Tijdschrift voor Allergie en Astma. 17, p. 21-28

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Voedselallergie: mosterd na de maaltijd?

Wichers, H. J., 27 May 2016, In : Voedingsmiddelentechnologie. 7, p. 29 1 p.

Research output: Contribution to journalArticleAcademicpeer-review

Voedseleiwitten en allergische reacties

Vissers, Y. M., Wichers, H. J. & Savelkoul, H. F. J., 2007, In : Nederlands Tijdschrift voor Allergie. 7, 5, p. 160-165

Research output: Contribution to journalArticleProfessional

Open Access

Water-soluble polysaccharide extracts from the oyster culinary-medicinal mushroom pleurotus ostreatus (Agaricomycetes) with HMGCR inhibitory activity

Gil-Ramírez, A., Smiderle, F. R., Morales, D., Govers, C., Synytsya, A., Wichers, H. J., Iacomini, M. & Soler-Rivas, C., 2017, In : International Journal of Medicinal Mushrooms. 19, 10, p. 879-892

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Wat zijn ze waard, die nieuwe eiwitten?

de Jong, G. A. H., Mes, J. J. & Wichers, H. J., Sep 2020, In : Voedingsindustrie : vakblad. 27, 6, p. 46-49

Research output: Contribution to journalArticleProfessional

Open Access

Wheat-derived arabinoxylans reduced M2-macrophage functional activity, but enhanced monocyte-recruitment capacity

Govers, C., Tang, Y., Stolte, E. H., Wichers, H. J. & Mes, J. J., 19 Aug 2020, In : Food & Function. 11, 8, p. 7073-7083

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

WLIP, a lipodepsipeptide of Pseudomonas 'reactans', as inhibitor of the symptoms of the brown blotch disease of Agaricus bisporus

Soler Rivas, C., Arpin, N., Olivier, J. M. & Wichers, H. J., 1999, In : Journal of Applied Microbiology. 86, 4, p. 635-641

Research output: Contribution to journalArticleAcademicpeer-review

36 Citations (Scopus)
Book

Managing allergens in food

Mills, C., Wichers, H. J. & Hoffmann-Sommergruber, K., 2007, Cambridge: Woodhead. 336 p. (Woodhead Publishing in food science, technology and nutrition)

Research output: Book/ReportBookAcademic

Book editing

Chemical and Biological Properties of Food Allergens

Jedrychowski, L. (ed.) & Wichers, H. J. (ed.), 2009, Boca Raton: CRC Press. 447 p. (Chemical and functional properties of food components)

Research output: Book/ReportBook editingAcademic

The Impact of Food Bioactives on Health: in vitro and ex vivo models

Verhoeckx, K. (ed.), Cotter, P. (ed.), Lopez-Exposito, I. (ed.), Lea, T. (ed.), Mackie, A. (ed.), Requena, T. (ed.), Swiatecka, D. (ed.) & Wichers, H. J. (ed.), 2015, Zeist: Springer International Publishing. 338 p.

Research output: Book/ReportBook editingAcademic

Open Access
53 Citations (Scopus)
Book review

Book review: Pectins and their manipulation

Wichers, H. J., 2004, In : Postharvest Biology and Technology. 32, 1, p. 119-120

Research output: Contribution to journalBook reviewProfessional

Chapter

Beneficial health effects of chitin and chitosan

Dong, L., Wichers, H. J. & Govers, C. C. F. M., Jan 2020, Chitin and Chitosan: Properties and Applications. van den Broek, L. A. M., Boeriu, C. G. & Stevens, C. V. (eds.). John Wiley and Sons, p. 145-164 (Wiley Series in Renewable Research).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Controlling the texture of fruit and vegetables : the role of oxidising enzymes

Wichers, H. J. & Boeriu, C., 2004, Texture in food : vol. 2 : Solid foods. Kilcast, D. (ed.). Cambridge: Woodhead, p. 295-320 537 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Future developments in allergy prevention : a matter of integrating medical, natural and social sciences

Gilissen, L. J. W. J., Wichers, H. J., Savelkoul, H. F. J. & Beers, G., 2005, Allergy Matters : new approaches to allergy prevention and management. Dr. Gilissen, L. J. E. J., Prof.dr. Wichers, H. J., Prof.dr.ir. Savelkoul, H. F. J. & Bogers, J. R. (eds.). p. 3-10 205 p. (Wageningen UR Frontis Series; no. 10).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Open Access

Geen peanuts

Wichers, H. J., 2005, Vliegwiel naar duurzaamheid : Innovatieve Acties Programma 2003-2004. Arnhem: Provincie Gelderland, p. 58-59 74 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Open Access

Immunomodulation by dietary mushroom compounds

Savelkoul, H. F. J., Lull Noguera, C. & Wichers, H. J., 2007, Inflammation and infection : The golden triangle : Food - microflora - host defence. Heidt, P. J., Midtvedt, T., Rusch, V. & van der Waaij, D. (eds.). Herborn-Dill, p. 37-62 118 p. (Old Herborn University Seminar Monograph; no. 20).

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Open Access

Immunomodulation by Food

van der Meer, I. M., Mes, J. J., Weijn, A. & Wichers, H. J., 2012, Multidisciplinary Approaches to Allergies. Gao, Z. S., Shen, H. H., Zheng, M., Frewer, L. J. & Gilissen, L. J. W. J. (eds.). Zhejiang University Press, p. 303-313 480 p. (Advanced topics in science and technology in China).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Immunomodulation by Food: Allergy Mitigation by Dietary Components

Wichers, H. J. & Mes, J. J., 2011, Food Allergies: Symptoms, Diagnosis, and Treatment. Rodgers, P. M. (ed.). Hauppauge, NY, USA: Nova Science Publicers, Inc., p. 79-94

Research output: Chapter in Book/Report/Conference proceedingChapter

Open Access
1 Citation (Scopus)

Immunomodulation by Food for Mitigating Allergic Disease

Mes, J. J. & Wichers, H. J., 2013, Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases. Watson, R. (ed.). United Kingdom: Academic Press, p. 451-460 680 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Immunomodulatory effects of mushroom B-glucans

Savelkoul, H. F. J., Chanput, W. & Wichers, H. J., 2013, Diet, immunity and inflammation, woodhead publishing series in food science, technology and nutrition no. 232. Calder, P. C. & Yaqoob, P. (eds.). p. 416-434 732 p. (Woodhead publishing series in food science, technology and nutrition; no. 232).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

2 Citations (Scopus)

Influence of food processing, digestion and the food matrix on allergenicity & cellular measures of allergenicity

Vissers, Y. M., Wichers, H. J. & Savelkoul, H. F. J., 2012, Multidisciplinary approaches to allergies. Gao, Z. S. (ed.). Berlin, p. 203-227 480 p. (Advanced topics in science and technology in China).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

4 Citations (Scopus)

Minimal processing and the allergenic properties of food

Wichers, H. J., 2007, Managing allergens in food. Mills, C., Wichers, H. J. & Hoffmann-Sommergruber, K. (eds.). Cambridge: Woodhead, p. 190-203 336 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Monitoring of and technological effects on allergenicity of proteins in the food industry

Wichers, H. J., Matser, A. M., van Amerongen, A., Wichers, J. & Soler-Rivas, C., 2004, Plant Food Allergens. Shewry, P. R. & Mills, E. N. C. (eds.). Oxford, UK: Blackwell Scientific and Medical Publishers, p. 196-212

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Pectins and pectolytic enzymes in relation to development and processing of green beans (Phaseolus vulgaris L.)

Recourt, K., Stolle-Smits, T., Laats, J. M., Beekhuizen, J. G., Ebbelaar, C. E. M., Voragen, A. G. J., Wichers, H. J. & van Dijk, C., 1996, Pectins and Pectinases. p. 399-404

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

3 Citations (Scopus)

Processing approaches to reducing allergenicity in proteins

Mills, E. N. C., Moreno, J., Sancho, A., Jenkins, J. A. & Wichers, H. J., 2004, Proteins in food processing. Yada, R. Y. (ed.). Cambridge: Woodhead, p. 396-418 704 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Citations (Scopus)