1984 …2018
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Research Output 1984 2018

2018
2 Citations (Scopus)
Open Access
Microfluidics
HEK293 Cells
G-Protein-Coupled Receptors
calcium
Calcium
2015

Progress report validation of parameters to determine unconsciousness during slaughter of veal calves

Gerritzen, M. A., Verhoeven, H. A. & Hindle, V. A., Mar 2015, Wageningen UR Livestock Research. 28 p. (Livestock Research rwport; no. 405)

Research output: Book/ReportReportProfessional

Open Access
48 Citations (Scopus)

Real-time imaging of microparticles and living cells with CMOS nanocapacitor arrays

Laborde, C., Pittino, F., Verhoeven, H. A., Lemay, S. G., Selmi, L., Jongsma, M. A. & Widdershoven, F. P., 2015, In : Nature Nanotechnology. 10, p. 791-795

Research output: Contribution to journalArticleAcademicpeer-review

microparticles
Labels
CMOS
Screening
platforms
2014

Synthesis of formic acid by enzymatic CO2 reduction with in situ cofactor regeneration

Corici, L. N., Frissen, A. E., Verhoeven, H. A., Beekwilder, M. J. & Boeriu, C. G., 2014.

Research output: Contribution to conferencePosterAcademic

2013
9 Citations (Scopus)

Phellinus linteus polysaccharide extracts increase the mitochondrial membrane potential and cause apoptotic death of THP-1 monocytes

van Griensven, L. J. L. D. & Verhoeven, H. A., 2013, In : Chinese Medicine. 8, 13 p., 25.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Mitochondrial Membrane Potential
Polysaccharides
Monocytes
Cause of Death
Agaricales
2012
85 Citations (Scopus)

A translational study “case report” on the small molecule “energy blocker” 3-bromopyruvate (3BP) as a potent anticancer agent: from bench side to bedside

Ko, Y. H., Verhoeven, H. A., Lee, M. J., Corbin, D. J., Vogl, T. J. & Pedersen, P. L., 2012, In : Journal of Bioenergetics and Biomembranes. 44, p. 163-170

Research output: Contribution to journalArticleAcademicpeer-review

Antineoplastic Agents
Neoplasms
Translational Medical Research
Oxidative Phosphorylation
Glycolysis
6 Citations (Scopus)

Flow cytometric evaluation of the effects of 3-bromopyruvate (3BP) and dichloracetate (DCA) on THP-1 cells: a multiparameter analysis

Verhoeven, H. A. & van Griensven, L. J. L. D., 2012, In : Journal of Bioenergetics and Biomembranes. 44, 1, p. 91-99

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Membrane Transport Proteins
K562 Cells
Melanoma
Leukemia
bromopyruvate
9 Citations (Scopus)

Solid Phase Micro-Extraction GC–MS Analysis of Natural Volatile Components in Melon and Rice

Verhoeven, H. A., Jonker, H. H., de Vos, C. H. & Hall, R. D., 2012, Plant metabolomics. Hardy, N. G. & Hall, R. D. (eds.). London, p. 85-99 (Methods in molecular biology; no. 860).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Fragrances
Crops
Gas chromatography
Mass spectrometry
Flavors
2011

Mushroom polysaccharide extracts cause human monocytic THP-1 cells to differentiate into macrophages or undergo apoptotic death. What signals are involved?

van Griensven, L. J. L. D. & Verhoeven, H. A., 2011, Proceedings of the 6th International Medicinal Mushroom Conference, Zagreb, Croatia, 25-29 September 2011. p. 3

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

2009
24 Citations (Scopus)

Automated procedure for candidate compound selection in GCMS metabolomics based on prediction of Kovats retention index

Mihaleva, V. V., Verhoeven, H. A., de Vos, C. H., Hall, R. D. & van Ham, R. C. H. J., 2009, In : Bioinformatics. 25, 6, p. 787-794

Research output: Contribution to journalArticleAcademicpeer-review

Metabolomics
Gas Chromatography-Mass Spectrometry
Libraries
Hits
Prediction
2008
20 Citations (Scopus)

Accurate mass error correction in liquid chromatography time-of-flight mass spectrometry based metabolomics

Mihaleva, V. V., Vorst, O. F. J., Maliepaard, C. A., Verhoeven, H. A., de Vos, C. H., Hall, R. D. & van Ham, R. C. H. J., 2008, In : Metabolomics. 4, 2, p. 171-182

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Boidae
Metabolomics
Automation
Liquid chromatography
Error correction
69 Citations (Scopus)

Is there a second fragrance gene in rice?

Fitzgerald, M. A., Hamilton, N. R. S., Calingacion, M. N., Verhoeven, H. A. & Butardo, V. M., 2008, In : Plant Biotechnology Journal. 6, 4, p. 416-423

Research output: Contribution to journalArticleAcademicpeer-review

aromatic compounds
odors
rice
alleles
Alleles
2007
3 Citations (Scopus)
Beta vulgaris
confocal laser scanning microscopy
protoplasts
flow cytometry
monitoring
2006
358 Citations (Scopus)

A liquid chromatography-mass spectrometry-based metabolome database for tomato

Moco, S. I. A., Bino, R. J., Vorst, O. F. J., Verhoeven, H. A., de Groot, J. C. W., van Beek, T. A., Vervoort, J. J. M. & de Vos, C. H., 2006, In : Plant Physiology. 141, 4, p. 1205-1218

Research output: Contribution to journalArticleAcademicpeer-review

metabolome
Metabolome
Lycopersicon esculentum
Liquid Chromatography
liquid chromatography

Metabolomics of tomato fruit volatiles during fruit development

Tikunov, Y. M., Lommen, A., de Vos, C., Verhoeven, H. A., Bino, R. J., Hall, R. D. & Bovy, A. G., 2006, Book of Abstracts Fourth International Congress on Plant Metabolomics, Reading, Berkshire, United Kingsom, 7-10 April 2006. p. 78

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

Molecular engineering of floral scent

Lücker, J., Verhoeven, H. A., van der Plas, L. H. W. & Bouwmeester, H. J., 2006, Biology of floral scent. Dudareva, N. & Pichersky, E. (eds.). Atlanta, USA: CRC Press, p. 321-337

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

18 Citations (Scopus)

Plant metabolomics strategies based upon quadrupole time of flight mass spectrometry (QTOF-MS)

Verhoeven, H. A., de Vos, C. H., Bino, R. J. & Hall, R. D., 2006, Plant Metabolomics. Saito, K., Dixon, R. A. & Willmitzer, L. (eds.). Berlin Heidelberg, p. 33-48 347 p. (Biotechnology and Forestry; no. 57).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

2005
367 Citations (Scopus)
Metabolomics
metabolomics
Lycopersicon esculentum
Fruit
data analysis
12 Citations (Scopus)

Metabolomics for the assessment of functional diversity and quality traits in plants

Hall, R. D., de Vos, C. H., Verhoeven, H. A. & Bino, R. J., 2005, Metabolic Profiling. Vaidyanathan, S., Harrigan, G. G. & Goodacre, R. (eds.). Boston: Springer, p. 31-44

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

2004
104 Citations (Scopus)

Increased and altered fragrance of tobacco plants after metabolic engineering using three monoterpene synthases from lemon

Lücker, J., Schwab, W., van Hautum, B., Blaas, J., van der Plas, L. H. W., Bouwmeester, H. J. & Verhoeven, H. A., 2004, In : Plant Physiology. 134, 1, p. 510-519

Research output: Contribution to journalArticleAcademicpeer-review

Metabolic Engineering
metabolic engineering
lemons
monoterpenoids
Tobacco
52 Citations (Scopus)

Metabolic engineering of monoterpende biosysnthesis: two step production of (+)-trans-Isopiperitenol by tobacco

Lücker, J., Schwab, W., Franssen, M. C. R., van der Plas, L. H. W., Bouwmeester, H. J. & Verhoeven, H. A., 2004, In : The Plant Journal. 39, 1, p. 135-145

Research output: Contribution to journalArticleAcademicpeer-review

Metabolic Engineering
metabolic engineering
Tobacco
tobacco
Mixed Function Oxygenases
2003
27 Citations (Scopus)

Domain swapping of Citrus limon monoterpene synthases: impact on enzymatic activity and product specifity.

el Tamer, M. K., Lucker, J., Bosch, D., Verhoeven, H. A., Verstappen, F. W. A., Schwab, W., van Tunen, A. J., Voragen, A. G. J., de Maagd, R. A. & Bouwmeester, H. J., 2003, In : Archives of Biochemistry and Biophysics. 411, p. 196-203

Research output: Contribution to journalArticleAcademicpeer-review

Citrus
Monoterpenes
Enzymes
Amino Acids
Molecular modeling

High resolution QTOF MS as a screening tool for plant metabolomics

Hall, R. D., Verhoeven, H. A., de Vos, C. H., Lommen, A. & Bino, R. J., 2003.

Research output: Contribution to conferenceAbstractAcademic

Identification of metabolic mutants

Verhoeven, H. A., de Vos, C. H., Maliepaard, C. A., Hall, R. D. & Bino, R. J., 2003, Proceedings workshop "Potential of metabolic profiling in plant science, Torino, Italy. p. 45-51

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Metabolomic profiling of activation-tagged Arabidopsis mutants using QTOF-MS

de Vos, C. H., Verhoeven, H. A., Aharoni, A., Pereira, A. B., Bino, R. J. & Hall, R. D., 2003.

Research output: Contribution to conferenceAbstractAcademic

Metabormatics for MS and development ideas

Lommen, A., Laue, G., Verhoeven, H. A., Nielen, M., Bouwmeester, H. J., de Vos, C. H., Hall, R. D., Gassmann, E. & Bino, R. J., 2003.

Research output: Contribution to conferenceAbstractAcademic

Plant metabolomics for plant breeding

Bino, R. J., Verhoeven, H. A., de Vos, C. H. & Hall, R. D., 2003, p. 1-11.

Research output: Contribution to conferenceAbstractAcademic

180 Citations (Scopus)

Regulation of floral scent production in petunia revealed by targeted metabolomics

Verdonk, J. C., de Vos, C. H., Verhoeven, H. A., Haring, M. A., van Tunen, A. J. & Schuurink, R. C., 2003, In : Phytochemistry. 62, p. 997-1008

Research output: Contribution to journalArticleAcademicpeer-review

Petunia
Metabolomics
Sesquiterpenes
metabolomics
odors
347 Citations (Scopus)

Terpenoid Metabolism in Wild-Type and Transgenic Arabidopsis Plants

Aharoni, A., Giri, A. P., Deuerlein, S., Griepink, F. C., de Kogel, W. J., Verstappen, F. W. A., Verhoeven, H. A., Jongsma, M. A., Schwab, W. & Bouwmeester, H. J., 2003, In : The Plant Cell. 15, 12, p. 2866-2884

Research output: Contribution to journalArticleAcademicpeer-review

Genetically Modified Plants
Terpenes
Arabidopsis
terpenoids
sesquiterpenoids
2002
121 Citations (Scopus)

Monoterpene biosynthesis in lemon (Citrus limon) cDNA isolation and functional analysis of four monoterpene synthases

Lücker, J., El Tamer, M. K., Schwab, W., Verstappen, F. W. A., van der Plas, L. H. W., Bouwmeester, H. J. & Verhoeven, H. A., 2002, In : European Journal of Biochemistry. 269, p. 3160-3161

Research output: Contribution to journalArticleAcademicpeer-review

Functional analysis
Monoterpenes
Citrus
Biosynthesis
Complementary DNA
2001
148 Citations (Scopus)

Expression of Clarkia S-linalool synthase in transgenic petunia plant results in the accumulation of S-linalyl-b-D-glucopyranoside

Lücker, J., Bouwmeester, H. J., Schwab, W., Blaas, J., van der Plas, L. H. W. & Verhoeven, H. A., 2001, In : The Plant Journal. 27, p. 315-324

Research output: Contribution to journalArticleAcademicpeer-review

Clarkia
Petunia
Genetically Modified Plants
linalool
genetically modified organisms
2000
401 Citations (Scopus)

Identification of the SAAT gene involved in strawberry flavor biogenesis by use of DNA micro-arrays

Aharoni, A., Keizer, L. C. P., Bouwmeester, H. J., Sun, Z., Alvarez-Huerta, M., Verhoeven, H. A., Blaas, J., van Houwelingen, A. M. M. L., de Vos, R. C. H., van der Voet, H., Jansen, R. C., Guis, M., Davis, R. W., Schena, M., van Tunen, A. J. & O'Connel, A. P., 2000, In : The Plant Cell. 12, p. 647-661

Research output: Contribution to journalArticleAcademicpeer-review

1999
4 Citations (Scopus)

Microprotoplast-mediated chromosome transfer (MMCT) for the direct production of monosomic addition lines

Ramulu, K. S., Dijkhuis, P., Krens, F. A. & Verhoeven, H. A., 1999, Plant cell culture protocols. Hall, R. D. (ed.). p. 227-242

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

1998

Genetic modification of flavour and fragrance production in plants

Verhoeven, H. A., Aharoni, A., Wein, M., Blaas, J., Bouwer, R. & van Tunen, A. J., 1998, Natural product analysis. Schreier, P., Herderich, M., Humpf, H. U. & Schwab, W. (eds.). p. 311-312

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

6 Citations (Scopus)
1997
13 Citations (Scopus)

Identification and molecular analysis of transgenic potato chromosomes transferred to tomato through microprotoplast fusion

Rutgers, E., Ramulu, K. S., Dijkhuis, P., Blaas, J., Krens, F. A. & Verhoeven, H. A., 1997, In : Theoretical and Applied Genetics. 94, 8, p. 1053-1059

Research output: Contribution to journalArticleAcademicpeer-review

Kanamycin Kinase
kanamycin kinase
Lycopersicon esculentum
Solanum tuberosum
Chromosomes
37 Citations (Scopus)

Solid-phase microextraction: artefact formation and its avoidance

Verhoeven, H. A., Beuerle, T. & Schwab, W., 1997, In : Chromatographia. 46, p. 63-66

Research output: Contribution to journalArticleAcademicpeer-review

1996

A transformation system for sugar beet based on a single cell type

Hall, R. D., Riksen-Bruinsma, T., Krens, F. A., Verhoeven, H. A., Lathouwers, J., Lommel, M., Rosquin, I., Weyens, G., LefObvre, M. P. & Dunwell, J. M., 1996, Proceedings IIRB Congress. p. 571-575

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

32 Citations (Scopus)

Expression of the JIM8 cell wall epitope in carrot somatic embryogenesis.

Toonen, M. A. J., Schmidt, E. D. L., Hendriks, T., Verhoeven, H. A., van Kammen, A. & de Vries, S. C., 1996, In : Planta. 200, p. 167-173

Research output: Contribution to journalArticleAcademicpeer-review

High amounts of nuclear DNA in tomato (Lycopersicon esculentum) pericarp

Bergervoet, J. H. W., Verhoeven, H. A., Gilissen, L. J. W. J. & Bino, R. J., 1996, In : Plant Science. 116, p. 141-145

Research output: Contribution to journalArticleAcademicpeer-review

48 Citations (Scopus)

High amounts of nuclear DNA in tomato (Lycopersicon esculentum Mill.) pericarp

Bergervoet, J. H. W., Verhoeven, H. A., Gilissen, L. J. W. J. & Bino, R. J., 1996, In : Plant Science. 116, p. 145-151

Research output: Contribution to journalArticleAcademicpeer-review

28 Citations (Scopus)

Intergeneric transfer of a partial genome and direct production of monosomic addition plants by microprotoplast fusion

Ramulu, K. S., Dijkhuis, R., Rutgers, E., Blaas, J., Krens, F. A., Verbeek, W. H. J., Colijn-Hooymans, C. M. & Verhoeven, H. A., 1996, In : Theoretical and Applied Genetics. 92, p. 316-325

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)

Microprotoplast-mediated transfer of single, specific chromosomes between sexually incompatible plants

Ramulu, K. S., Dijkhuis, P., Rutgers, E., Blaas, J., Krens, F. A., Dons, J. J. M., Colijn-Hooymans, C. M. & Verhoeven, H. A., 1996, In : Genome. 39, p. 921-933

Research output: Contribution to journalArticleAcademicpeer-review

1995

Analysis of sexual progeny of interspecific (micro)protoplast fusion hybrids.

Jacobsen, E., Ramulu, K. S., Ramanna, M. S. & Verhoeven, H. A., 1995, Abstract 4th Int. Symp. Molecular biology of the potato, Wageningen (1995).

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

Cremart: A new chemical for efficient induction of micronuclei in cells and protoplasts for partial genome transfer

Ramulu, K. S., Dijkhuis, P., Famelaer, I., Cardi, T. & Verhoeven, H. A., 1995, In : Plant Cell Reports. 13, p. 687-691

Research output: Contribution to journalArticleAcademicpeer-review

Development of single cells labeled with the monoclonal antibody JIM8 in carrot somatic embryogenesis.

Toonen, M. A. J., Schmidt, E. D. L., Hendriks, T., Verhoeven, H. A. & de Vries, S. C., 1995, Abstractbook Symp. Fluorescent proteins and applications. Inst. Molecular Medicine, Palo Alto, USA. p. 16

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

1994
5 Citations (Scopus)

Cytological characterization of isolated sperm cells of perennial ryegrass (Lolium perenne L.).

van der Maas, H. M., de Jong, E. R., van Aelst, A. C., Verhoeven, H. A., Krens, F. A. & van Went, J. L., 1994, In : Protoplasma. 178, p. 48-56

Research output: Contribution to journalArticleAcademicpeer-review

Lolium
Lolium perenne
Spermatozoa
spermatozoa
Mitochondria
90 Citations (Scopus)

Description of somatic-embryo-forming single cells in carrot suspension cultures employing video cell tracking.

Toonen, M. A. J., Hendriks, T., Schmidt, E. D. L., Verhoeven, H. A., van Kammen, A. & de Vries, S. C., 1994, In : Planta. 194, p. 565-572

Research output: Contribution to journalArticleAcademicpeer-review

The JIM8 cell wall epitope in carrot single cell somatic embryogenesis.

Toonen, M. A. J., Schmidt, E. D. L., Hendriks, T., Verhoeven, H. A. & de Vries, S. C., 1994, Abstractbook 4th Int. Congr. Plant Molecular Biology, Amsterdam. p. 644

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

1993

Autofluorescence in potato tuber phellem: location and time course of appearance during tuber information.

Hendriks, T., van Eck, J. W. & Verhoeven, H. A., 1993, Biotechnology applications of microinjection, microscopic imaging, and fluorescence: Proceedings of the First European Workshop held in London, England, April 21-24, 1992. Bach, P. H., Reynolds, C. H., Clark, J. M., Mottley, J. & Poole, P. L. (eds.). New York.: Plenum Press, p. 633-637

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review