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Research Output 1990 2019

2019
1 Citation (Scopus)

An early β-glucan bath during embryo development increases larval size of Nile tilapia

de Jesus, R. B., Petit, J., Pilarski, F., Wiegertjes, G. F., Koch, J. F. A., de Oliveira, C. A. F. & Zanuzzo, F. S., Jul 2019, In : Aquaculture Research. 50, 7, p. 2012-2014

Research output: Contribution to journalLetterAcademicpeer-review

Open Access
Saponins
Immersion
Zebrafish
Larva
Fertilization

Evidence of trained immunity in a fish: Conserved features in cArp macrophages

Petit, J., Embregts, C. W. E., Forlenza, M. & Wiegertjes, G. F., 1 Jul 2019, In : Journal of Immunology. 203, 1, p. 216-224 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Carps
Immunity
Fishes
Macrophages
Head Kidney
3 Citations (Scopus)

Intra-muscular and oral vaccination using a Koi Herpesvirus ORF25 DNA vaccine does not confer protection in common carp (Cyprinus carpio L.)

Embregts, C. W. E., Tadmor-Levi, R., Veselý, T., Pokorová, D., David, L., Wiegertjes, G. F. & Forlenza, M., Feb 2019, In : Fish and Shellfish Immunology. 85, p. 90-98

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Cyprinid herpesvirus 3
oral vaccination
DNA Vaccines
vaccination
vaccine

Modulation of innate immunity in carp: Diverse approaches to ß-glucanmediated responses

Petit, J., 2019, Wageningen: Wageningen University. 202 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access

Paralogs of Common Carp Granulocyte Colony-Stimulating Factor (G-CSF) Have Different Functions Regarding Development, Trafficking and Activation of Neutrophils

Katakura, F., Nishiya, K., Wentzel, A. S., Hino, E., Miyamae, J., Okano, M., Wiegertjes, G. F. & Moritomo, T., 19 Feb 2019, In : Frontiers in Immunology. 10, 1 p.

Research output: Contribution to journalArticleAcademicpeer-review

Neutrophil Activation
Carps
Granulocyte Colony-Stimulating Factor
Neutrophils
Kidney
2 Citations (Scopus)

Pichia pastoris yeast as a vehicle for oral vaccination of larval and adult teleosts

Embregts, C. W. E., Reyes-Lopez, F., Pall, A. C., Stratmann, A., Tort, L., Lorenzen, N., Engell-Sorensen, K., Wiegertjes, G. F., Forlenza, M., Sunyer, J. O. & Parra, D., Feb 2019, In : Fish and Shellfish Immunology. 85, p. 52-60

Research output: Contribution to journalArticleAcademicpeer-review

oral vaccination
Pichia pastoris
vaccination
Green Fluorescent Proteins
teleost

Preface to the special issue ‘targeting fish vaccination’

Lorenzen, N., Tafalla, C. & Wiegertjes, G. F., Feb 2019, In : Fish and Shellfish Immunology. 85, p. 1-2

Research output: Contribution to journalEditorialAcademic

1 Citation (Scopus)

Studies Into β-Glucan Recognition in Fish Suggests a Key Role for the C-Type Lectin Pathway

Petit, J., Bailey, E. C., Wheeler, R. T., de Oliveira, C. A. F., Forlenza, M. & Wiegertjes, G. F., Feb 2019, In : Frontiers in Immunology. 10, 1 p., 280.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
C-Type Lectins
beta-Glucans
Carps
Macrophages
Genes

The kinetics of cellular and humoral immune responses of common carp to presporogonic development of the myxozoan Sphaerospora molnari

Korytář, T., Wiegertjes, G. F., Zusková, E., Tomanová, A., Lisnerová, M., Patra, S., Sieranski, V., Šíma, R., Born-Torrijos, A., Wentzel, A. S., Blasco-Monleon, S., Yanes-Roca, C., Policar, T. & Holzer, A. S., 6 May 2019, In : Parasites & Vectors. 12, 1, 1 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Carps
Humoral Immunity
Cellular Immunity
Parasites
Fishes

Through the looking glass: trypanosome infections in zebrafish: seeing is believing

Dóró, E., 2019, Wageningen: Wageningen University. 206 p.

Research output: Thesisinternal PhD, WUAcademic

7 Citations (Scopus)

Vaccination of carp against SVCV with an oral DNA vaccine or an insect cells-based subunit vaccine

Embregts, C. W. E., Rigaudeau, D., Tacchi, L., Pijlman, G. P., Kampers, L., Veselý, T., Pokorová, D., Boudinot, P., Wiegertjes, G. F. & Forlenza, M., Feb 2019, In : Fish and Shellfish Immunology. 85, p. 66-77

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Subunit Vaccines
DNA Vaccines
vaccination
subunit vaccines
vaccine
2018
10 Citations (Scopus)

Exploring fish microbial communities to mitigate emerging diseases in aquaculture

de Bruijn, I., Liu, Y., Wiegertjes, G. F. & Raaijmakers, J. M., 1 Jan 2018, In : FEMS microbiology ecology. 94, 1, fix161.

Research output: Contribution to journalShort surveyAcademicpeer-review

Aquaculture
aquaculture
microbial community
Fishes
Shellfish
Open Access
Saponins
Immersion
Zebrafish
Larva
Anti-Bacterial Agents

Innate immune response to trypanosome infection in zebrafish

Jacobs, S. H., Doro, E., Hammond, F., van Eyndhoven, L. C., Nguyen-Chi, M., Wiegertjes, G. & Forlenza, M., 2018, p. P-073.

Research output: Contribution to conferencePosterAcademic

Innate immune response to trypanosome infection in zebrafish

Jacobs, S. H., Doro, E., Hammond, F., van Eyndhoven, L. C., Nguyen-Chi, M., Wiegertjes, G. & Forlenza, M., 2018, p. 125-125.

Research output: Contribution to conferenceAbstractAcademic

Onderzoek naar het ontstaan van darmontstekingen: het zebravismodel

Brugman, S., Forlenza, M. & Wiegertjes, G., 2018, In : Biotechniek. 57, 1, p. 9-14

Research output: Contribution to journalArticleProfessional

Open Access

Saponin induces an inflammatory phenotype and microbiome shift in zebrafish larvae

Lopez Nadal, A., Peggs, D., Wiegertjes, G. & Brugman, S., 2018.

Research output: Contribution to conferenceAbstractAcademic

Studying metabolic pathways in macrophages of carp

Wentzel, A. S., Petit, J., de Boer, V. C. J., Forlenza, M. & Wiegertjes, G., 2018, p. 94-95.

Research output: Contribution to conferenceAbstractAcademic

1 Citation (Scopus)

Targeting fish vaccination

Wiegertjes, G. F., 2018, In : Bulletin of the European Association of Fish Pathologists. 38, 3, p. 98-103

Research output: Contribution to journalArticleAcademicpeer-review

vaccination
targeting
Fishes
Vaccination
Vaccines

Training carp macrophages: establishment of an in vitro screening model for trained immunity in teleost fish

Petit, J., Embregts, C. W. E., Forlenza, M. & Wiegertjes, G., 2018.

Research output: Contribution to conferenceAbstractAcademic

Training the immune system to become as healthy as a fish

Petit, J., Embregts, C. W. E., Wentzel, A. S., Forlenza, M. & Wiegertjes, G., 2018.

Research output: Contribution to conferenceAbstractAcademic

Transcriptome analysis reveals several b-glucan recognition pathways in carp macrophages

Petit, J., Wentzel, A. S., Forlenza, M. & Wiegertjes, G., 2018, p. 136-137.

Research output: Contribution to conferenceAbstractAcademic

Vaccine development against carp viruses: Integrating adaptive immunity

Embregts, C. W. E., 2018, Wageningen: Wageningen University. 308 p.

Research output: Thesisinternal PhD, WUAcademic

2017
9 Citations (Scopus)

Carp Il10a and Il10b exert identical biological activities in vitro, but are differentially regulated in vivo

Piazzon, M. C., Wentzel, A. S., Wiegertjes, G. F. & Forlenza, M., 2017, In : Developmental and Comparative Immunology. 67, p. 350-360

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Carps
Interleukin-10
Phagocytes
Genome
Synteny
16 Citations (Scopus)

Conserved Fever Pathways across Vertebrates: A Herpesvirus Expressed Decoy TNF-α Receptor Delays Behavioral Fever in Fish

Rakus, K., Ronsmans, M., Forlenza, M., Boutier, M., Piazzon, M. C., Jazowiecka-rakus, J., Gatherer, D., Athanasiadis, A., Farnir, F., Davison, A. J., Boudinot, P., Michiels, T., Wiegertjes, G. F. & Vanderplasschen, A., 2017, In : Cell Host & Microbe. 21, 2, p. 244-253

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Tumor Necrosis Factor Receptors
Herpesviridae
Vertebrates
Fever
Tumor Necrosis Factor-alpha

Development of a DNA vaccine against SVCV and characterization of local and systemic immune responses after intramuscular and oral delivery

Embregts, C. W. E., Boudinot, P., Lunazzi, A., Rigaudeau, D., Lorenzen, N., Veselý, T., Wiegertjes, G. & Forlenza, M., 2017.

Research output: Contribution to conferenceAbstractAcademic

Development of DNA vaccine against KHV and characterization of immune responses after intramuscular and oral vaccination

Embregts, C. W. E., Veselý, T., David, L., Tadmor-Levi, R., Wiegertjes, G. & Forlenza, M., 2017.

Research output: Contribution to conferenceAbstractAcademic

8 Citations (Scopus)

Genomic and transcriptomic approaches to study immunology in cyprinids: What is next?

Petit, J., David, L., Dirks, R. & Wiegertjes, G. F., 2017, In : Developmental and Comparative Immunology. 75, p. 48-62

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Cyprinidae
Allergy and Immunology
Physiological Phenomena
Ploidies
Gene Expression Profiling

Increased immune activities in "trained" common carp macrophages

Petit, J., Embregts, C. W. E., Wentzel, A. S., Forlenza, M. & Wiegertjes, G., 2017. 1 p.

Research output: Contribution to conferenceAbstractAcademic

Innate immunity of carp : fishing for receptors

Fink, I., 2017, Wageningen: Wageningen University. 240 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access
Carps
Innate Immunity
Macrophages
Fishes
Pattern Recognition Receptors
13 Citations (Scopus)

Intramuscular DNA vaccination of juvenile carp against spring viremia of carp virus induces full protection and Establishes a Virus-Specific B and T Cell Response

Embregts, C. W. E., Rigaudeau, D., Veselỳ, T., Pokorová, D., Lorenzen, N., Petit, J., Houel, A., Dauber, M., Schütze, H., Boudinot, P., Wiegertjes, G. F. & Forlenza, M., 24 Oct 2017, In : Frontiers in Immunology. 8, 16 p., 1340.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Carps
Viremia
Vaccination
B-Lymphocytes
Viruses
3 Citations (Scopus)

Transcriptome sequence of the bloodstream form of Trypanoplasma borreli, a hematozoic parasite of fish transmitted by leeches

Carrington, M., Dóró, E., Forlenza, M., Wiegertjes, G. F. & Kelly, S., 2017, In : Genome Announcements. 5, 9, e01712-16.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Leeches
Carps
Transcriptome
Fishes
Parasites
2016
14 Citations (Scopus)

A full-body transcriptome and proteome resource for the European common carp

Kolder, I. C. R. M., van der Plas-Duivesteijn, S. J., Tan, G., Wiegertjes, G. F., Forlenza, M., Guler, A. T., Travin, D. Y., Nakao, M., Moritomo, T., Irnazarow, I., den Dunnen, J. T., Anvar, S. Y., Jansen, H. J., Dirks, R. P., Palmblad, M., Lenhard, B., Henkel, C. V. & Spaink, H. P., 2016, In : BMC Genomics. 17, 1, 701.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Carps
Proteome
Transcriptome
Zebrafish
Fishes

Conservation of macrophage polarization in fish

Wentzel, A. S., Petit, J., Fink, I. R., Forlenza, M. & Wiegertjes, G., 2016, p. 54.

Research output: Contribution to conferenceAbstractAcademic

Fishes
Macrophages
Carps
Interleukin-13
Cytokines

Establishment and characterization of a trypanosome infection in zebrafish

Doro, E., Wiegertjes, G. & Forlenza, M., 2016, p. C2035-26 . 2 p.

Research output: Contribution to conferenceAbstractAcademic

Facing the challenge of a functional characterization of toll-like receptor (TLR)1 and TLR2 in common carp

Fink, I. R., Forlenza, M., Pietretti, D. & Wiegertjes, G., 2016, p. 76. 1 p.

Research output: Contribution to conferenceAbstractAcademic

Toll-Like Receptor 1
Shellfish
Carps
Allergy and Immunology
Fishes

Increased oxygen but not nitrogen radicals in trained carp macrophages

Petit, J., Wentzel, A. S. & Wiegertjes, G., 2016.

Research output: Contribution to conferenceAbstractAcademic

14 Citations (Scopus)

Infectious bronchitis coronavirus limits interferon production by inducing a host shutoff that requires accessory protein 5b

Kint, J., Langereis, M. A., Maier, H. J., Britton, P., van Kuppeveld, F. J., Koumans, J., Wiegertjes, G. F. & Forlenza, M., 2016, In : Journal of Virology. 90, 16, p. 7519-7528

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
infectious bronchitis
Coronavirus
Coronavirinae
Bronchitis
interferons
40 Citations (Scopus)

Long-lived effects of administering β-glucans: Indications for trained immunity in fish

Petit, J. & Wiegertjes, G. F., 2016, In : Developmental and Comparative Immunology. 64, p. 93-102

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
beta-Glucans
Immunity
Fishes
Immune System
Macrophages

Looking through transgenic zebrafish to reveal novel mechanisms of host-parasite interaction: In vivo real-time imaging of a trypanosome infection

Forlenza, M., Doro, E., Hammond, F., Pei, H. & Wiegertjes, G., 2016, p. 92. 1 p.

Research output: Contribution to conferenceAbstractAcademic

Host-Parasite Interactions
Shellfish
Trypanosomiasis
Zebrafish
Allergy and Immunology
14 Citations (Scopus)

Molecular and functional characterization of Toll-like receptor (Tlr)1 and Tlr2 in common carp (Cyprinus carpio)

Fink, I. R., Pietretti, D., Voogdt, C. G. P., Westphal, A. H., Savelkoul, H. F. J., Forlenza, M. & Wiegertjes, G. F., 2016, In : Fish and Shellfish Immunology. 56, p. 70-83

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Toll-Like Receptor 1
Cyprinus carpio
ligand
carp
Ligands

Oral DNA vaccination of carp; involved mechanisms and immune responses

Embregts, C. W. E., Wiegertjes, G. & Forlenza, M., 2016, p. C2035 29. 1 p.

Research output: Contribution to conferenceAbstractAcademic

40 Citations (Scopus)

Polarization of immune responses in fish: The 'macrophages first' point of view

Wiegertjes, G. F., Wentzel, A. S., Spaink, H. P., Elks, P. M. & Fink, I. R., 2016, In : Molecular Immunology. 69, p. 146-156 69.

Research output: Contribution to journalArticleAcademicpeer-review

Fishes
Macrophages
Cytokines
Arginase
Parasitic Diseases

Preface to the special issue: Intestinal immunity

Wiegertjes, G. F. & Lee, W. J., 2016, In : Developmental and Comparative Immunology. 64, p. 1-1

Research output: Contribution to journalEditorialAcademic

TargetFish - Targeted disease prophylaxis in European fish farming

Wiegertjes, G. F., Lorenzen, N., Secombes, C. J., Collet, B., Fischer, U., Tafalla, C., Parra, D., Scapigliati, G., Boudinot, P., Evensen, Ø., Adams, A., Toffan, A., Buchmann, K., Vesely, T., David, L., Mulero, V., Smith, P., Aspehaug, V., Engell-Sørensen, K., Sober, J. & 9 othersWallis, T., Rød, T., Flores, M., Stratmann, A., Christofilogiannis, P., Tobar, J., Henriksen, N., Sigholt, T. & De Las Heras, A., 2016, In : Bulletin of the European Association of Fish Pathologists. 36, 1, p. 52-56 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2015
Infectious bronchitis virus
Interferon Type I
Proteins
Interferons
Viruses