Floris van Delft

prof.dr.

Special Professor, Organic Chemistry
VLAG

https://orcid.org/0000-0003-4455-7727

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9 Similar Researchers

Cycloaddition Chemical Compounds

Quinones Chemical Compounds

Cycloparaffins Chemical Compounds

Proteins Engineering & Materials Science

Antibodies Engineering & Materials Science

Azides Chemical Compounds

Tyrosine Medicine & Life Sciences

Oxidation Chemical Compounds

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Research Output 2016 2019

9 Article
1 Chapter
1 Digital or Visual Products

Highly efficient mono-functionalization of knob-in-hole antibodies with strain-promoted click chemistry

Bruins, J. J., van de Wouw, C., Koen, W., Lina, B., Albada, B. & van Delft, F. L., 8 Jul 2019, In : Journal of the American Chemical Society. 4, p. 11801-11807 4.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Click Chemistry

Knobs

Monoclonal antibodies

Antibodies

Dimers

1 Citation (Scopus)

Inducible, selective labeling of proteins via enzymatic oxidation of tyrosine

Bruins, J. J., van de Wouw, C., Keijzer, J. F., Albada, B. & van Delft, F. L., 4 Jun 2019, Methods in Molecular Biology. Hertfordshire: Springer, p. 357-368 12 p. (Methods in Molecular Biology; vol. 2012).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

Tyrosine

Cycloaddition Reaction

Proteins

Alkynes

Monophenol Monooxygenase

7 Citations (Scopus)

Enzymatic strategies for (near) clinical development of antibody-drug conjugates

van Berkel, S. S. & van Delft, F. L., Dec 2018, In : Drug Discovery Today: Technologies. 30, p. 3-10

Research output: Contribution to journal › Article › Academic › peer-review

Antibodies

Pharmaceutical Preparations

Poisons

Neoplasms

Technology

6 Citations (Scopus)

Kinetics of the Strain-Promoted Oxidation-Controlled Cycloalkyne-1,2-quinone Cycloaddition: Experimental and Theoretical Studies

Escorihuela Fuentes, J., Das, A., Looijen, W. J. E., van Delft, F. L., Aquino, A. J. A., Lischka, H. & Zuilhof, H., 2018, In : Journal of Organic Chemistry. 83, 1, p. 244-252

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Cycloparaffins

Cycloaddition

Discrete Fourier transforms

Oxidation

Kinetics

8 Citations (Scopus)