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Fingerprint Dive into the research topics where Floris van Delft is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 9 Similar Researchers
Cycloaddition Chemical Compounds
Quinones Chemical Compounds
Cycloparaffins Chemical Compounds
Proteins Engineering & Materials Science
Antibodies Engineering & Materials Science
Azides Chemical Compounds
Tyrosine Medicine & Life Sciences
Oxidation Chemical Compounds

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Research Output 2016 2019

  • 9 Article
  • 1 Chapter
  • 1 Digital or Visual Products

Highly efficient mono-functionalization of knob-in-hole antibodies with strain-promoted click chemistry

Bruins, J. J., van de Wouw, C., Koen, W., Lina, B., Albada, B. & van Delft, F. L., 8 Jul 2019, In : Journal of the American Chemical Society. 4, p. 11801-11807 4.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Click Chemistry
Knobs
Monoclonal antibodies
Antibodies
Dimers
1 Citation (Scopus)

Inducible, selective labeling of proteins via enzymatic oxidation of tyrosine

Bruins, J. J., van de Wouw, C., Keijzer, J. F., Albada, B. & van Delft, F. L., 4 Jun 2019, Methods in Molecular Biology. Hertfordshire: Springer, p. 357-368 12 p. (Methods in Molecular Biology; vol. 2012).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Tyrosine
Cycloaddition Reaction
Proteins
Alkynes
Monophenol Monooxygenase
7 Citations (Scopus)

Enzymatic strategies for (near) clinical development of antibody-drug conjugates

van Berkel, S. S. & van Delft, F. L., Dec 2018, In : Drug Discovery Today: Technologies. 30, p. 3-10

Research output: Contribution to journalArticleAcademicpeer-review

Antibodies
Pharmaceutical Preparations
Poisons
Neoplasms
Technology
6 Citations (Scopus)

Kinetics of the Strain-Promoted Oxidation-Controlled Cycloalkyne-1,2-quinone Cycloaddition: Experimental and Theoretical Studies

Escorihuela Fuentes, J., Das, A., Looijen, W. J. E., van Delft, F. L., Aquino, A. J. A., Lischka, H. & Zuilhof, H., 2018, In : Journal of Organic Chemistry. 83, 1, p. 244-252

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Cycloparaffins
Cycloaddition
Discrete Fourier transforms
Oxidation
Kinetics
8 Citations (Scopus)

Orthogonal, dual protein labelling by tandem cycloaddition of strained alkenes and alkynes to: Ortho -quinones and azides

Bruins, J. J., Blanco-Ania, D., van der Doef, V., van Delft, F. L. & Albada, B., 1 Jan 2018, In : Chemical Communications. 54, 53, p. 7338-7341

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Quinones
Alkynes
Azides
Cycloaddition
Alkenes

Projects 2015 2020