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- 1 Similar Profiles
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Nicotinamide nucleotide transhydrogenase dysfunction transcriptionally impacts mitochondrial β-oxidation and neuromuscular junction in M. Gastrocnemius of 24-day-old mice
Song, J., Keijer, J., Bekkenkamp-Grovenstein, M., Humphry, M., Carmone, C. & Grefte, S., Dec 2025, In: International Journal of Biological Macromolecules. 332, 148609.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Link opens in a new tab Citation (Scopus) -
NNT dysfunction blunts the hypoxic response of the gastrocnemius muscle of 24-day-old mice, impacting proteostasis and neuromuscular junction
Song, J., van der Stelt, I., Bekebrede, A. F., Jaklofsky, M. T. J., Carmone, C., Keijer, J. & Grefte, S., 6 Mar 2025.Research output: Contribution to conference › Poster › Academic
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Six-hour hypoxia-induced protein degradation in M. gastrocnemius of 24-day-old mice by activating FOXO1 and suppressing AKT-mTORC1
Song, J., Jaklofsky, M., Carmone, C., de Boer, V., Wever, N., Keijer, J. & Grefte, S., Apr 2025, In: American Journal of Physiology - Endocrinology and Metabolism. 328, 4, p. E620-E632Research output: Contribution to journal › Article › Academic › peer-review
Open Access4 Link opens in a new tab Citations (Scopus) -
Impact of metabolic substrates on the activity of nicotinamide nucleotide transhydrogenase (NNT)
van der Stelt, I., Bekkenkamp-Grovenstein, M., Carmone, C., Koopman, W. J. H. & Keijer, J., 27 Aug 2024.Research output: Contribution to conference › Poster › Academic
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Metabolic substrate conditions direct activity of nicotinamide nucleotide transhydrogenase (NNT), thereby modifying mitochondrial pyruvate metabolism
van der Stelt, I., Bekkenkamp-Grovenstein, M., Carmone, C., Koopman, W. J. H. & Keijer, J., 1 Sept 2024, In: Biochimica et Biophysica Acta. B, Bioenergetics. 1865, Supplement, 149417.Research output: Contribution to journal › Abstract › Academic
Datasets
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mRNA-seq profiles of gastrocnemius of 24-day-old Nnt-mut and Nnt-wt male mice
Song, J. (Creator), Keijer, J. (Creator), Bekkenkamp-Grovenstein, M. (Creator), Humphry, M. (Creator), Carmone, C. (Creator) & Grefte, S. (Creator), Wageningen University & Research, 6 Feb 2024
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE255162
Dataset
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mRNAseq profiles of gastrocnemius of 24-day-old Nnt-wt male mouse exposed to hypoxia
Song, J. (Creator), Jaklofsky, M. (Creator), Carmone, C. (Creator), de Boer, V. (Creator), Wever, N. (Creator), Keijer, J. (Creator) & Grefte, S. (Creator), Wageningen University & Research, 9 Feb 2024
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE255522
Dataset
Activities
- 3 Oral presentation
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Absence of mitochondrial nicotinamide nucleotide transhydrogenase triggers glucocorticoid-associated gene expression in the hippocampus of infant mice
Romijnders-van der Stelt, I. (Speaker), Song, J. (Contributor), Yang, J. (Contributor), Bekebrede, A. (Contributor), Jaklofsky, M. (Contributor), Bekkenkamp-Grovenstein, M. (Contributor), Carmone, C. (Contributor), Grefte, S. (Contributor), Koopman, W. (Contributor) & Keijer, J. (Contributor)
27 May 2025Activity: Talk/presentation/lecture › Oral presentation › Academic
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Nicotinamide nucleotide transhydrogenase (NNT) dysfunction as well as hypoxia exposure impacts on developmental processes of the M. gastrocnemius of 24-day-old mice
Song, J. (Speaker), Bekkenkamp-Grovenstein, M. (Contributor), Carmone, C. (Contributor), Jaklofsky, M. (Contributor), Keijer, J. (Contributor) & Grefte, S. (Contributor)
25 Sept 2024Activity: Talk/presentation/lecture › Oral presentation › Academic
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Nicotinamide nucleotide transhydrogenase (NNT) dysfunction impacts on lipid metabolism, and neuromuscular junction (NMJ) in M. gastrocnemius of 24-day-old mice
Song, J. (Speaker), Bekkenkamp-Grovenstein, M. (Contributor), Carmone, C. (Contributor), Keijer, J. (Contributor) & Grefte, S. (Contributor)
20 Jun 2024Activity: Talk/presentation/lecture › Oral presentation › Academic