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Research Output 2003 2019

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Article
2019

Effect of removal of bacteria on the biomass and extracellular carbohydrate productivity of Botryococcus braunii

Gouveia, J. D., Moers, A., Griekspoor, Y., van den Broek, L. A. M., Springer, J., Sijtsma, L., Sipkema, D., Wijffels, R. H. & Barbosa, M. J., 26 Jun 2019, In : Journal of Applied Phycology. 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
carbohydrate
carbohydrates
productivity
bacterium
biomass
2018
8 Citations (Scopus)

Chitinase Chi1 from Myceliophthora thermophila C1, a Thermostable Enzyme for Chitin and Chitosan Depolymerization

Krolicka, M., Hinz, S. W. A., Koetsier, M. J., Joosten, R., Eggink, G., van den Broek, B. & Boeriu, C. G., Feb 2018, In : Journal of Agricultural and Food Chemistry. 66, 7, p. 1658-1669

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Myceliophthora thermophila
Chitinases
Depolymerization
Chitin
depolymerization

MAB2.0 project: Integrating algae production into wastewater treatment

Nagy, B. J., Mako, M., Erdelyi, I., Abiusi, F., Reith, J. H. & van den Broek, L. A. M., 2018, In : The EurBiotech Journal. 2, 1, p. 10–23 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Algae
Wastewater treatment
Feedstocks
Wastewater
Flue gases
1 Citation (Scopus)
Open Access
Tetraselmis suecica
Gelation
gelation
Complex Mixtures
algae
2 Citations (Scopus)
Open Access
Polyesters
Crystallization
Thermodynamic properties
Glass transition temperature
1,4-butanediol
13 Citations (Scopus)

Water-soluble chitosan derivatives and pH-responsive hydrogels by selective C-6 oxidation mediated by TEMPO-laccase redox system

Botelho da Silva, S., Krolicka, M., van den Broek, L. A. M., Frissen, A. E. & Boeriu, C. G., 15 Apr 2018, In : Carbohydrate Polymers. 186, p. 299-309

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Laccase
Hydrogels
Chitosan
Derivatives
Oxidation

β-N-Acetylglucosaminidase MthNAG from Myceliophthora thermophila C1, a thermostable enzyme for production of N-acetylglucosamine from chitin

Krolicka, M., Hinz, S. W. A., Koetsier, M. J., Eggink, G., van den Broek, L. A. M. & Boeriu, C. G., Sep 2018, In : Applied Microbiology and Biotechnology. 102, 17, p. 7441–7454

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Acetylglucosaminidase
Chitin
Acetylglucosamine
Enzymes
Chitinases
2017
19 Citations (Scopus)

Biorefinery of microalgal soluble proteins by sequential processing and membrane filtration

Safi, C., Olivieri, G., Pina Campos, R., Engelen-Smit, N., Mulder, W. J., van den Broek, L. A. M. & Sijtsma, L., 2017, In : Bioresource Technology. 225, p. 151-158

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Ultrafiltration
ultrafiltration
membrane
Proteins
Membranes
13 Citations (Scopus)

Botryococcus braunii strains compared for biomass productivity, hydrocarbon and carbohydrate content

Gouveia, J. D. G., Ruiz, J., van den Broek, B., Hesselink, T., Peters, S. A., Kleinegris, D. M. M., Smith, A. G., van der Veen, D., Barbosa, M. J. & Wijffels, R. H., 2017, In : Journal of Biotechnology. 248, p. 77-86

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Carbohydrates
Hydrocarbons
Biomass
Productivity
Weights and Measures
19 Citations (Scopus)

Energy consumption and water-soluble protein release by cell wall disruption of Nannochloropsis gaditana

Safi, C., Cabas Rodriguez, L., Mulder, W. J., Engelen-Smit, N., Spekking, W., van den Broek, L. A. M., Olivieri, G. & Sijtsma, L., 2017, In : Bioresource Technology. 239, p. 204-210

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Energy utilization
Cells
Proteins
protein
Water
16 Citations (Scopus)

Green compressed fluid technologies for downstream processing of Scenedesmus obliquus in a biorefinery approach

Gilbert-López, B., Mendiola, J. A., van den Broek, L. A. M., Houweling-Tan, B., Sijtsma, L., Cifuentes, A., Herrero, M. & Ibáñez, E., 1 Jun 2017, In : Algal Research. 24, p. 111-121

Research output: Contribution to journalArticleAcademicpeer-review

Scenedesmus obliquus
biorefining
algae
supercritical fluid extraction
high performance liquid chromatography
61 Citations (Scopus)
Open Access
Hermetia illucens
edible insects
Alphitobius diaperinus
Tenebrio
Tenebrio molitor
2016

Polysaccharides in Human Health Care

van Dam, J. E. G., van den Broek, L. A. M. & Boeriu, C. G., 2016, In : Natural Product Communications. 12, 6, p. 821-830

Research output: Contribution to journalArticleAcademicpeer-review

health services
Polysaccharides
human health
polysaccharides
Delivery of Health Care
2015
142 Citations (Scopus)

Chitosan films and blends for packaging material

van den Broek, L. A. M., Knoop, J. R. I., Kappen, F. H. J. & Boeriu, C. G., 2015, In : Carbohydrate Polymers. 116, p. 237-242

Research output: Contribution to journalArticleAcademicpeer-review

Packaging materials
Chitosan
Polysaccharides
Packaging
Polymers
46 Citations (Scopus)

Downstream processing of Isochrysis galbana: a step towards microalgal biorefinery

Gilbert-López, B., Mendiola, J. A., Fontecha, J., van den Broek, L. A. M., Sijtsma, L., Cifuentes, A., Herrero, M. & Ibáñez, E., 2015, In : Green Chemistry. 17, 9, p. 4599-4609

Research output: Contribution to journalArticleAcademicpeer-review

Processing
Algae
ethanol
Ethanol
alga

How much bio is in there? Can stable isotopes be used to determine the bio-based content of products?

van den Broek, L. A. M., van der Veer, G. & van der Zee, M., 2015, In : Bioplastics Magazine. 10, 5, p. 18-22

Research output: Contribution to journalArticleProfessional

Open Access
14 Citations (Scopus)

Lipase-catalyzed synthesis of oligoesters of 2,5-furandicarboxylic acid with aliphatic diols

Cruz-Izquierdo, Á., van den Broek, L. A. M., Serra, J. L., Llama, M. J. & Boeriu, C. G., 2015, In : Pure and Applied Chemistry. 87, 1, p. 59-69

Research output: Contribution to journalArticleAcademicpeer-review

Lipases
Lipase
Chain length
Acids
Substrates
2014
30 Citations (Scopus)

Cationic polymers for successful flocculation of marine microalgae

't Lam, G. P., Vermuë, M. H., Olivieri, G., van den Broek, L. A. M., Barbosa, M. J., Eppink, M. H. M., Wijffels, R. H. & Kleinegris, D. M. M., 2014, In : Bioresource Technology. 169, p. 804-807

Research output: Contribution to journalArticleAcademicpeer-review

Flocculation
flocculation
Polymers
polymer
Recovery
2013
13 Citations (Scopus)

Computer-aided solvent screening for biocatalysis

Abildskov, J., van Leeuwen, M. B., Boeriu, C. G. & van den Broek, L. A. M., 2013, In : Journal of Molecular Catalysis. B, Enzymatic. 85-86, p. 200-213

Research output: Contribution to journalArticleAcademicpeer-review

Biocatalysis
Octanols
Screening
Lipases
Lipase
30 Citations (Scopus)

Enzymatic synthesis of oligo- and polysaccharide fatty acid esters

van den Broek, L. A. M. & Boeriu, C. G., 2013, In : Carbohydrate Polymers. 93, 1, p. 65-72

Research output: Contribution to journalArticleAcademicpeer-review

Oligosaccharides
Polysaccharides
Fatty acids
Esters
Fatty Acids
12 Citations (Scopus)

Production methods for heparosan, a precursor of heparin and heparan sulfate

Chavaroche, A. A. E., van den Broek, L. A. M. & Eggink, G., 2013, In : Carbohydrate Polymers. 93, 1, p. 38-47

Research output: Contribution to journalArticleAcademicpeer-review

Heparitin Sulfate
Heparin
Molecules
Oncology
heparosan

Production methods for hyaluronan

Boeriu, C. G., Springer, J., Kooy, F. K., van den Broek, L. A. M. & Eggink, G., 2013, In : International Journal of Carbohydrate Chemistry. 2013, 14 p., 624967.

Research output: Contribution to journalArticleAcademicpeer-review

Hyaluronic Acid
Polysaccharides
Metabolic Engineering
Biopolymers
Genetic Engineering
2012
13 Citations (Scopus)

Biocatalytic acylation of sugar alcohols by 3-(4-hydroxyphenyl)propionic acid

Croitoru, R., Fitigau, F., van den Broek, L. A. M., Frissen, A. E. & Boeriu, C. G., 2012, In : Process Biochemistry. 47, 12, p. 1894-1902

Research output: Contribution to journalArticleAcademicpeer-review

Sugar Alcohols
Xylitol
Acylation
Propionic acid
Sorbitol
10 Citations (Scopus)
Open Access
Aesculus
Pseudomonas syringae
Pathogens
disease course
Phloem
11 Citations (Scopus)

Synthesis of heparosan oligosaccharides by Pasteurella multocida PmHS2 single-action transferases

Chavaroche, A. A. E., van den Broek, L. A. M., Boeriu, C. G. & Eggink, G., 2012, In : Applied Microbiology and Biotechnology. 95, 5, p. 1199-1210

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Pasteurella multocida
Transferases
Oligosaccharides
Polymerization
Uridine Diphosphate Sugars
2011
14 Citations (Scopus)
Uridine Diphosphate Sugars
Pasteurella multocida
Glycosyltransferases
Hydrolases
Polymerization
4 Citations (Scopus)

Lipase catalyzed synthesis of aromatic esters of sugar alcohols

Croitoru, R., van den Broek, L. A. M., Frissen, A. E., Davidescu, C. M., Peter, F. & Boeriu, C. G., 2011, In : World Academy of Science, Engineering and Technology. 76, p. 484-489

Research output: Contribution to journalArticleAcademicpeer-review

Sugar Alcohols
Lipase
Esters
Sol-gels
tert-Butyl Alcohol
16 Citations (Scopus)

Purification and characterization of novel fibrinolytic proteases as potential antithrombotic agents from earthworm Perionyx excavatus

phan, T. T. B., Ta, T. D., Nguyen, D. T. X. & van den Broek, L. A. M., 2011, In : AMB Express. 1, 11 p., 1:26.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Oligochaeta
Fibrinolytic Agents
Peptide Hydrolases
Fibrin
Phenylmethylsulfonyl Fluoride
2010
16 Citations (Scopus)
Oligosaccharides
Fructose
Acylation
Molecular sieves
Esters
2008
15 Citations (Scopus)

Determination of Pepsin-Susceptible and Pepsin-Resistant Epitopes in Native and Heat-Treated Peanut Allergen Ara h 1

van Boxtel, E. L., Koppelman, S. J., van den Broek, L. A. M. & Gruppen, H., 2008, In : Journal of Agricultural and Food Chemistry. 56, 6, p. 2223-2230

Research output: Contribution to journalArticleAcademicpeer-review

Pepsin A
pepsin
allergens
epitopes
peanuts
8 Citations (Scopus)

Heat denaturation of Brazil nut allergen Ber e 1 in relation to food processing

van Boxtel, E. L., Koppelman, S. J., van den Broek, L. A. M. & Gruppen, H., 2008, In : Food Chemistry. 110, 4, p. 904-908

Research output: Contribution to journalArticleAcademicpeer-review

Bertholletia
Brazil nuts
Food processing
Food Handling
Denaturation
41 Citations (Scopus)

Legumin allergens from peanuts and soybeans : Effects of denaturation and aggregation on allergenicity

van Boxtel, E. L., van den Broek, L. A. M., Koppelman, S. J. & Gruppen, H., 2008, In : Molecular Nutrition & Food Research. 52, 6, p. 674-682

Research output: Contribution to journalArticleAcademicpeer-review

legumin
allergenicity
allergens
denaturation
Soybeans
2007
17 Citations (Scopus)

Peanut Allergen Ara h 1 Interacts with Proanthocyanidins into Higher Molecular Weight Complexes

van Boxtel, E. L., van den Broek, L. A. M., Koppelman, S. J., Vincken, J. P. & Gruppen, H., 2007, In : Journal of Agricultural and Food Chemistry. 55, 21, p. 8772-8778

Research output: Contribution to journalArticleAcademicpeer-review

Proanthocyanidins
allergens
proanthocyanidins
peanuts
Molecular Weight
2006
37 Citations (Scopus)

Allergen Ara h 1 Occurs in Peanuts as a Large Oligomer Rather Than as a Trimer

van Boxtel, E. L., van Beers, M. M. C., Koppelman, S. J., van den Broek, L. A. M. & Gruppen, H., 2006, In : Journal of Agricultural and Food Chemistry. 54, 19, p. 7180-7186

Research output: Contribution to journalArticleAcademicpeer-review

allergens
Oligomers
Allergens
peanuts
allergenicity
1 Citation (Scopus)

Expanded bed adsorption as a fast technique for the large-scale purification of the complete isoform pool of Ber e 1, the major allergen from Brazil nuts.

van Boxtel, E. L., van Koningsveld, G. A., Koppelman, S. J., van den Broek, L. A. M., Voragen, A. G. J. & Gruppen, H., 2006, In : Molecular Nutrition & Food Research. 50, 3, p. 275-281

Research output: Contribution to journalArticleAcademicpeer-review

Bertholletia
Brazil nuts
allergens
Allergens
Adsorption
26 Citations (Scopus)
alpha-Galactosidase
Mutagenesis
Site-Directed Mutagenesis
Enzymes
Mutation
49 Citations (Scopus)

Structural Rearrangements of Sucrose Phosphorylase from Bifidobacterium adolescentis during Sucrose Conversion

Mirza, O., Skov, L. K., Sprogoe, D., van den Broek, L. A. M., Beldman, G., Kastrup, J. S. & Gajhede, M., 2006, In : Journal of Biological Chemistry. 281, 46, p. 35576-35584

Research output: Contribution to journalArticleAcademicpeer-review

sucrose phosphorylase
Sucrose
Catalytic Domain
Glucose
Mutagenesis
2005
34 Citations (Scopus)

Bifidobacterium longum endogalactanase liberates galactotriose from type I galactans

Hinz, S. W. A., Pastink, M. I., van den Broek, L. A. M., Vincken, J. P. & Voragen, A. G. J., 2005, In : Applied and Environmental Microbiology. 71, 9, p. 5501-5510

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Galactans
Bifidobacterium longum
galactans
enzyme
Enzymes
79 Citations (Scopus)

Cloning and characterization of arabinoxylan arabinofuranofydrolases-D3 (AXHd3) from Bifidobacterium adolescentis DSM20083

van den Broek, L. A. M., Lloyd, R. M., Beldman, G., Verdoes, J. C., McCleary, B. V. & Voragen, A. G. J., 2005, In : Applied Microbiology and Biotechnology. 67, 5, p. 641-647

Research output: Contribution to journalArticleAcademicpeer-review

Organism Cloning
Open Reading Frames
Arabinose
Genes
Glycoside Hydrolases
9 Citations (Scopus)

Conformational stability of the potato serine protease ihibitor group

Pouvreau, L. A. M., Gruppen, H., van Koningsveld, G. A., van den Broek, L. A. M. & Voragen, A. G. J., 2005, In : Journal of Agricultural and Food Chemistry. 53, 8, p. 3191-3196

Research output: Contribution to journalArticleAcademicpeer-review

Serine Proteinase Inhibitors
Serine Proteases
serine proteinases
Solanum tuberosum
proteinase inhibitors
8 Citations (Scopus)

Glycosyl hydrolases from Bifidobacterium adolescentis DSM20083. An overview

van den Broek, L. A. M., Hinz, S. W. A., Beldman, G., Doeswijk-Voragen, C. H. L., Vincken, J. P. & Voragen, A. G. J., 2005, In : Lait. 85, 1-2, p. 125-133

Research output: Contribution to journalArticleAcademicpeer-review

Bifidobacterium adolescentis
glycosidases
Hydrolases
Oligosaccharides
oligosaccharides
9 Citations (Scopus)

Structure and stability of the potato cysteine protease inhibitor group (Cv. Elkana)

Pouvreau, L. A. M., Kroef, C. H. M., Gruppen, H., van Koningsveld, G. A., van den Broek, L. A. M. & Voragen, A. G. J., 2005, In : Journal of Agricultural and Food Chemistry. 53, 14, p. 5739-5746

Research output: Contribution to journalArticleAcademicpeer-review

Cysteine Proteinase Inhibitors
cysteine proteinase inhibitors
Solanum tuberosum
potatoes
Protein Isoforms
2004
61 Citations (Scopus)

Crystal structure of sucrose phosphorylase from Bifidobacterium adolescentis.

Sprogoe, D., van den Broek, L. A. M., Mirza, O., Kastrup, J. S., Voragen, A. G. J., Gajhede, M. & Skov, L. K., 2004, In : Biochemistry. 43, 5, p. 1156-1162

Research output: Contribution to journalArticleAcademicpeer-review

sucrose phosphorylase
Crystal structure
Catalytic Domain
Enzymes
Dimers
55 Citations (Scopus)

Physico-chemical and transglucosylation properties of recombinant sucrose phosphorylase from Bifidobacterium adolescentis DSM20083.

van den Broek, L. A. M., van Boxtel, E. L., Kievit, R. P., Verhoef, R. P., Beldman, G. & Voragen, A. G. J., 2004, In : Applied Microbiology and Biotechnology. 65, 2, p. 219-227

Research output: Contribution to journalArticleAcademicpeer-review

sucrose phosphorylase
Sucrose
Arabinose
Enzymes
Plasmids
51 Citations (Scopus)

ß-Glactosidase from Bifidobacterium adolescentis DSM20083 prefers ß(1,4)-galactosides over lactose

Hinz, S. W. A., van den Broek, L. A. M., Beldman, G. & Vincken, J. P., 2004, In : Applied Microbiology and Biotechnology. 66, 3, p. 276-284

Research output: Contribution to journalArticleAcademicpeer-review

Galactosides
Lactose
Galactosidases
Cellobiose
Maltose
10 Citations (Scopus)

Structural characterization of potato protease inhibitor I (Cv. Bintje) after expression in Pichia pastoris

van den Broek, L. A. M., Pouvreau, L. A. M., Lommerse, G., Schipper, B., van Koningsveld, G. A. & Gruppen, H., 2004, In : Journal of Agricultural and Food Chemistry. 52, p. 4928-4934

Research output: Contribution to journalArticleAcademicpeer-review

Pichia pastoris
Pichia
Solanum tuberosum
proteinase inhibitors
Protease Inhibitors
5 Citations (Scopus)
Serine Proteinase Inhibitors
serine proteinases
Solanum tuberosum
proteinase inhibitors
potatoes
2003
25 Citations (Scopus)

Cloning and characterization of two a-glucosidases from Bifidobacterium adolescentis DSM20083.

van den Broek, L. A. M., Struijs, K., Verdoes, J. C., Beldman, G. & Voragen, A. G. J., 2003, In : Applied Microbiology and Biotechnology. 61, p. 55-60

Research output: Contribution to journalArticleAcademicpeer-review

Glucosidases
Glucosides
Sucrose
Organism Cloning
Trehalose
42 Citations (Scopus)
Serine Proteinase Inhibitors
serine proteinases
Solanum tuberosum
proteinase inhibitors
Protease Inhibitors