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Research Output 2002 2019

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2019
2 Citations (Scopus)

In vivo transcriptomes of Streptococcus suis reveal genes required for niche-specific adaptation and pathogenesis

Arenas, J., Bossers-de Vries, R., Harders-Westerveen, J., Buys, H., Ruuls-van Stalle, L. M. F., Stockhofe-Zurwieden, N., Zaccaria, E., Tommassen, J., Wells, J. M., Smith, H. E. & de Greeff, A., 7 Apr 2019, In : Virulence. 10, 1, p. 334-351

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Streptococcus suis
Transcriptome
Virulence Factors
Genes
Swine
1 Citation (Scopus)

Molecular typing of Streptococcus suis strains isolated from diseased and healthy pigs between 1996-2016

Louise Prüfer, T., Rohde, J., Verspohl, J., Rohde, M., De Greeff, A., Willenborg, J. & Valentin-Weigand, P., 1 Jan 2019, In : PLoS ONE. 14, 1, e0210801.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Streptococcus suis
Molecular Typing
serotypes
Swine
Genes
2016
4 Citations (Scopus)

FlpS, the FNR-like protein of streptococcus suis is an essential, oxygen-sensing activator of the arginine deiminase system

Willenborg, J., Koczula, A., Fulde, M., de Greeff, A., Beineke, A., Eisenreich, W., Huber, C., Seitz, M., Valentin-Weigand, P. & Goethe, R., 2016, In : Pathogens. 5, 3, 51.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Streptococcus suis
Oxygen
Proteins
Arginine
Carbon
2 Citations (Scopus)

Increased fat and polyunsaturated fatty acid content in sow gestation diet has no effect on gene expression in progeny during the first 7 days of life

de Greeff, A., Bikker, P., Smit-Heinsbroek, A., Bruininx, E., Zwolschen, H., Fijten, H. P. D., Zetteler, P., Vastenhouw, S. A., Smits, M. A. & Rebel, J. M. J., 2016, In : Journal of Animal Physiology and Animal Nutrition. 100, 1, p. 127-135

Research output: Contribution to journalArticleAcademicpeer-review

Unsaturated Fatty Acids
sows
piglets
polyunsaturated fatty acids
High Fat Diet
7 Citations (Scopus)

Invasive pneumococcal disease leads to activation and hyperreactivity of platelets

Tunjungputri, R. N., de Jonge, M. I., de Greeff, A., van Selm, S., Buys-Bergen, H., Harders-Westerveen, J. F., Stockhofe-Zurwieden, N., Urbanus, R. T., De Groot, P. G., Smith, H. E., van der Ven, A. J. & de Mast, Q., 2016, In : Thrombosis Research. 144, p. 123-126

Research output: Contribution to journalArticleAcademicpeer-review

Pneumococcal Infections
Platelet Activation
Blood Vessels
Swine
9 Citations (Scopus)

Pneumococcal colonization and invasive disease studied in a porcine model

de Greeff, A., van Selm, S., Buys, H., Harders-Westerveen, J. F., Tunjungputri, R. N., de Mast, Q., van der Ven, A. J., Stockhofe-Zurwieden, N., de Jonge, M. I. & Smith, H. E., 2016, In : BMC Microbiology. 16, 1, 102.

Research output: Contribution to journalArticleAcademicpeer-review

Swine
Infectious Arthritis
Bacteremia
Streptococcus pneumoniae
Pneumococcal Infections
13 Citations (Scopus)

Rapid detection of Streptococcus uberis in raw milk by loop-mediated isothermal amplification

Cornelissen, J. B. W. J., De Greeff, A., Heuvelink, A. E., Swarts, M., Smith, H. E. & Van der Wal, F. J., 2016, In : Journal of Dairy Science. 99, 6, p. 4270-4281

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Streptococcus uberis
raw milk
Streptococcus
Milk
assays
5 Citations (Scopus)

Simultaneous Quantification and Differentiation of Streptococcus suis Serotypes 2 and 9 by Quantitative Real-time PCR, Evaluated in Tonsillar and Nasal Samples of Pigs

Dekker, N., Daemen, I., Verstappen, K. M., de Greeff, A., Smith, H. E. & Duim, B., 2016, In : Pathogens. 5, 3, 46.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Streptococcus suis
Nose
Real-Time Polymerase Chain Reaction
Swine
Serogroup
7 Citations (Scopus)

Supplementation of piglets with nutrient-dense complex milk replacer improves intestinal development and microbial fermentation

de Greeff, A., Resink, J. W., van Hees, H. M. J., Ruuls, L., Klaassen, G. J., Rouwers, S. M. G. & Stockhofe-Zurwieden, N., 1 Mar 2016, In : Journal of Animal Science. 94, 3, p. 1012-1019 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

milk replacer
Weaning
Fermentation
piglets
Milk
2015
22 Citations (Scopus)

Host-pathogen interaction at the intestinal mucosa correlates with zoonotic potential of Streptococcus suis

Ferrando, M. L., De Greeff, A., Van Rooijen, W. J. M., Stockhofe-Zurwieden, N., Nielsen, J., Wichgers Schreur, P. J., Pannekoek, Y., Heuvelink, A., Van Der Ende, A., Smith, H. & Schultsz, C., 2015, In : The Journal of Infectious Diseases. 212, 1, p. 95-105

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Streptococcus suis
Host-Pathogen Interactions
Zoonoses
Intestinal Mucosa
Epithelial Cells
2014
3 Citations (Scopus)

A naturally occurring nucleotide polymorphism in the orf2/folc promoter is associated with Streptococcus suis virulence

de Greeff, A., Buys, H., Wells, J. M. & Smith, H. E., 2014, In : BMC Microbiology. 14, 1, 264.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Streptococcus suis
Open Reading Frames
Virulence
Nucleotides
Protein Databases
24 Citations (Scopus)

Carbohydrate Availability Regulates Virulence Gene Expression in Streptococcus suis

Ferrando, M. L., van Baarlen, P., Orrù, G., Piga, R., Bongers, R. S., Wels, M., de Greeff, A., Smith, H. & Wells, J. M., 2014, In : PLoS ONE. 9, 3, 16 p., e89334.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Streptococcus suis
Gene expression
Virulence
virulence
Glucans
25 Citations (Scopus)

Control of Competence for DNA Transformation in Streptococcus suis by Genetically Transferable Pherotypes

Zaccaria, E., van Baarlen, P., de Greeff, A., Morrison, D. A., Smith, H. & Wells, J. M., 2014, In : PLoS ONE. 9, 6, 8 p., e99394.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
DNA Transformation Competence
Streptococcus suis
Pathogens
Mental Competency
Pheromones
24 Citations (Scopus)

Latest developments on Streptococcus suis: an emerging zoonotic pathogen: part 1

Segura, M., Zheng, H., de Greeff, A., Gao, G. F., Grenier, D., Jiang, Y., Chengping, L., Maskell, D., Oishi, K., Okura, M., Osawa, R., Schultsz, C., Schwerk, C., Sekizaki, T., Smith, H., Srimanote, P., Takamatsu, D., Tang, J., Tenenbaum, T., Tharavichitkul, P. & 7 othersHoa, N. T., Valentin-Weigand, P., Wells, J. M., Wertheim, H., Zhu, B., Xu, J. & Gottschalk, M., 2014, In : Future Microbiology. 9, 4, p. 441-444

Research output: Contribution to journalArticleAcademicpeer-review

Streptococcus suis
Zoonoses
Canada
China
Communicable Disease Control
20 Citations (Scopus)

Latest developments on Streptococcus suis: an emerging zoonotic pathogen: part 2

Segura, M., Zheng, H., de Greeff, A., Gao, G. F., Gremier, D., Jiang, Y., Chengping, L., Maskell, D., Oishi, K., Okura, M., Osawa, R., Schultsz, C., Schwerk, C., Sekizaki, T., Smith, H., Srimanote, P., Takamatsu, D., Tang, J., Tenenbaum, T., Tharavichitkul, P. & 7 othersHoa, N. T., Valentin-Weigand, P., Wells, J. M., Wertheim, H., Zhu, B., Xu, J. & Gottschalk, M., 2014, In : Future Microbiology. 9, 5, p. 587-591

Research output: Contribution to journalArticleAcademicpeer-review

Streptococcus suis
Zoonoses
Swine
Education
Microbiology
26 Citations (Scopus)

The Ccpa regulon of Streptococcus suis reveals novel insights into the regulation of the streptococcal central carbon metabolism by binding of CcpA to two distinct binding motifs.

Willenborg, J., de Greeff, A., Jarek, M., Valentin-Weigand, P. & Goethe, R., 2014, In : Molecular Microbiology. 92, 1, p. 61-83

Research output: Contribution to journalArticleAcademicpeer-review

Streptococcus suis
Regulon
Staphylococcal Protein A
Carbon
Streptococcus
2013
11 Citations (Scopus)

Early host response in the mammary gland after experimental Streptococcus uberis challenge in heifers

de Greeff, A., Zadoks, R. N., Ruuls, L., Toussaint, M., Nguyen, T. K., Downing, A., Rebel, J. M. J., Stockhofe-Zurwieden, N. & Smith, H. E., 2013, In : Journal of Dairy Science. 96, 6, p. 3723-3736

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Streptococcus uberis
Mastitis
Human Mammary Glands
Streptococcus
mammary glands
2011
42 Citations (Scopus)

ArgR is an essential local transcriptional regulator of the arcABC-operon in Streptococcus suis and crucial for biological fitness in acidic environment

Fulde, M., Willenborg, J., de Greeff, A., Benga, L., Smith, H. E., Valentin-Weigand, P. & Goethe, R., 2011, In : Microbiology. 157, 2, p. 572-582

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Streptococcus suis
Operon
Arginine
Chromatin Immunoprecipitation
Electrophoretic Mobility Shift Assay
33 Citations (Scopus)

Genetic diversity of Streptococcus suis isolates as determined by comparative genome hybridization

de Greeff, A., Wisselink, H. J., de Bree, F. M., Schultsz, C., Baums, C. G., Ngo Thi, H., Stockhofe-Zurwieden, N. & Smith, H. E., 2011, In : BMC Microbiology. 11, 15 p., 161.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Streptococcus suis
Comparative Genomic Hybridization
Virulence
Genes
Zoonoses
31 Citations (Scopus)

Strengthening insights into host responses to mastitis infection in ruminants by combining heterogeneous microarray data sources

Genini, S., Badaoui, B., Sclep, G., Bishop, S. C., Waddington, D., Pinard van der Laan, M. H., Klopp, C., Cabau, C., Seyfert, H. M., Petzl, W., Jensen, K., Glass, E. J., de Greeff, A., Smith, H. E., Smits, M. A., Olsaker, I., Boman, G. M., Pisoni, G., Moroni, P., Castiglioni, B. & 6 othersCremonesi, P., del Corvo, M., Foulon, E., Foucras, G., Rupp, R. & Giuffra, E., 2011, In : BMC Genomics. 12, 17 p., 225.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Mastitis
Information Storage and Retrieval
Ruminants
Meta-Analysis
Lipid Metabolism
2010
29 Citations (Scopus)

ApuA, a multifunctional x-glucan-degrading enzyme of Streptococcus suis, mediates adhesion to porcine epithelium and mucus

Ferrando, M. L., Fuentes, S., de Greeff, A., Smith, H. E. & Wells, J., 2010, In : Microbiology. 156, p. 2818-2828

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Streptococcus suis
Glucans
Mucus
Swine
Epithelium
10 Citations (Scopus)

Effect of organically and conventionally produced diets on jejunal gene expression in chickens

de Greeff, A., Huber, M., van de Vijver, L. P. L., Swinkels, W. J. C., Parmentier, H. K. & Rebel, J. M. J., 2010, In : British Journal of Nutrition. 103, 5, p. 696-702

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Chickens
Diet
Gene Expression
Genes
Cholesterol
20 Citations (Scopus)

Involvement of NF-¿B and MAP-kinases in the transcriptional response of alveolar macrophages to Streptococcus suis

de Greeff, A., Benga, A., Wichgers, P. J., Valentin-Weigand, P., Rebel, J. M. J. & Smith, H. E., 2010, In : Veterinary Microbiology. 141, 1-2, p. 59-67

Research output: Contribution to journalArticleAcademicpeer-review

Streptococcus suis
Alveolar Macrophages
mitogen-activated protein kinase
macrophages
Phosphotransferases
2003
23 Citations (Scopus)

Lipoprotein signal peptidase of Streptococcus suis serotype 2

de Greeff, A., Buijs, H., van Alphen, L. & Smith, H. E., 2003, In : Microbiology. 149, 6, p. 1399-1407

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Streptococcus suis
Lipoproteins
Escherichia coli
Leucyl Aminopeptidase
Glycerides
2002
120 Citations (Scopus)

Contribution of fibronectin-binding protein to pathogenesis of Streptococcus suis serotype 2

de Greeff, A., Buys, H., Verhaar, R., Dijkstra, J., van Alphen, L. & Smit, H. E., 2002, In : Infection and Immunity. 70, 3, p. 1319-1325

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Streptococcus suis
Fibronectins
Carrier Proteins
Fibrinogen
Infection
8 Citations (Scopus)

Distribution of environmentally regulated genes of Streptococcus suis serotype 2 among S-suis serotypes and other organisms

de Greeff, A., Buijs, H., Verhaar, R., van Alphen, L. & Smith, H. E., 2002, In : Journal of Clinical Microbiology. 40, 9, p. 3261-3268

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Streptococcus suis
Genes
Virulence Factors
Streptococcus pneumoniae
Streptococcus
25 Citations (Scopus)

Response regulator important in pathogenesis of Streptococcus suis serotype 2

de Greeff, A., Buijs, H., van Alphen, L. & Smith, H. E., 2002, In : Microbial Pathogenesis. 33, 4, p. 185-192

Research output: Contribution to journalArticleAcademicpeer-review

Streptococcus suis
Protoplasts
Virulence Factors
Proteins
Growth