Research output per year
Research output per year
Fingerprint
Dive into the research topics where Ad Peijnenburg is active. These topic labels come from the works of this person. Together they form a unique fingerprint. If staff members have published prior to their WUR affiliation, it is possible that the publication overview, Fingerprint and network diagram are incomplete.
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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In vitro relative potencies of perfluoroalkyl substances (PFASs) based on gene expression changes in human HepaRG liver cells
Louisse, J., Fragki, S. S., Rijkers, D. E. M. C., Janssen, A. W. F., Staats, M., Zeilmaker, M. J., Piersma, A. H., Luijten, M., Hoogenboom, L. A. P. & Peijnenburg, A. A. C. M., 24 May 2022. 1 p.Research output: Contribution to conference › Poster
Open Access -
Novel Insights into Pyrrolizidine Alkaloid Toxicity and Implications for Risk Assessment: Occurrence, Genotoxicity, Toxicokinetics, Risk Assessment-A Workshop Report
Schrenk, D., Fahrer, J., Allemang, A., Fu, P., Lin, G., Mahony, C., Mulder, P. P. J., Peijnenburg, A., Pfuhler, S., Rietjens, I. M. C. M., Sachse, B., Steinhoff, B., These, A., Troutman, J. & Wiesner, J., Feb 2022, In: Planta Medica. 88, 02, p. 98-117Research output: Contribution to journal › Article › Academic › peer-review
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Application of in vitro hepatic clearance data and physiologically based kinetic modeling for the estimation of species differences in internal exposure
Louisse, J., Pinckaers, N. E. T., Beekmann, K., Peijnenburg, A. A. C. M. & Punt, A., 24 Mar 2021.Research output: Contribution to conference › Poster
Open Access -
Correction: Cytochrome P450 expression, induction and activity in human induced pluripotent stem cell-derived intestinal organoids and comparison with primary human intestinal epithelial cells and Caco-2 cells
Janssen, A. W. F., Duivenvoorde, L. P. M., Rijkers, D., Nijssen, R., Peijnenburg, A. A. C. M., van der Zande, M. & Louisse, J., 17 Feb 2021, In: Archives of Toxicology. 95, 3, p. 923 1 p.Research output: Contribution to journal › Comment/Letter to the editor › Academic
Open Access -
Cytochrome P450 expression, induction and activity in human induced pluripotent stem cell-derived intestinal organoids and comparison with primary human intestinal epithelial cells and Caco-2 cells
Janssen, A. W. F., Duivenvoorde, L. P. M., Rijkers, D., Nijssen, R., Peijnenburg, A. A. C. M., van der Zande, M. & Louisse, J., Mar 2021, In: Archives of Toxicology. 95, 3, p. 907-922Research output: Contribution to journal › Article › Academic › peer-review
Open Access4 Citations (Scopus)
Datasets
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Fxr-deficiency in mouse liver slices aggravates cyclosporin A toxicity by upregulation of pro-inflammatory genes and downregulation of genes involved in mitochondrial functions
Szalowska, E. (Creator), Pronk, T. (Creator) & Peijnenburg, A. (Creator), RIKILT Wageningen UR, 22 Oct 2015
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE63457
Dataset
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Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?
Fragki, S. S. (Creator), Dirven, H. (Creator), Fletcher, T. (Creator), Grasl-Kraupp, B. (Creator), Bjerve Gützkow, K. (Creator), Hoogenboom, R. (Creator), Kersten, S. (Creator), Lindeman, B. (Creator), Louisse, J. (Creator), Peijnenburg, A. (Creator), Piersma, A. H. (Creator), Princen, H. M. G. (Creator), Uhl, M. (Creator), Westerhout, J. (Creator), Zeilmaker, M. J. (Creator) & Luijten, M. (Creator), National Institute for Public Health and the Environment (RIVM), 23 Apr 2021
DOI: 10.6084/m9.figshare.14420432
Dataset
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The impact of PPARα activation on whole genome gene expression in human precision-cut liver slices
Janssen, A. (Creator), Bretzel, B. (Creator), Stoopen, G. (Creator), Berends, F. J. (Creator), Janssen, I. M. (Creator), Peijnenburg, A. (Creator) & Kersten, S. (Creator), Wageningen University, 23 Nov 2015
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE71731
Dataset
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Model steatogenic compounds (amiodarone, valproic acid, and tetracycline) alter lipid metabolism by different mechanisms in mouse liver slices [Cholestatic compounds exposures]
Szalowska, E. (Creator), van der Burg, B. (Creator), Man, H. (Creator), Hendriksen, P. (Creator) & Peijnenburg, A. (Creator), RIKILT Wageningen UR, 23 Dec 2013
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE51544
Dataset
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Expression data from human Jurkat T cells exposed to 31 compounds
Shao, J. (Creator), Katika, M. R. (Creator), Schmeits, P. C. (Creator), Hendriksen, P. (Creator), van Loveren, H. (Creator), Peijnenburg, A. (Creator) & Volger, O. (Creator), Rikilt - Institute of Food Safety, 22 Jul 2013
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE46909
Dataset
Activities
- 5 Oral presentation
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WURlive 14: Minder proefdieren, maar hoe?
Ad Peijnenburg (Speaker) & Katharina Kardinal-Janke (Speaker)
12 Oct 2021Activity: Talk or presentation › Oral presentation › Professional
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In vitro-in silico-based assessment of species differences in kinetics: towards harmonization of in vitro clearance studies
Jochem Louisse (Speaker), Nicole Pinckaers (Contributor), Sandra Coecke (Contributor), Ad Peijnenburg (Contributor) & Ans Punt (Contributor)
23 Aug 2021 → 2 Sep 2021Activity: Talk or presentation › Oral presentation › Academic
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European network of high-quality laboratories assessing efficiently the relevance of fully animal-free thyroid mechanistic methods
Barbara Birk (Speaker), Toine Bovee (Contributor), Laureano Cuevas Beltran (Contributor), Flavio Cinato (Contributor), Annamaria Colacci (Contributor), Silvia Dotti (Contributor), Claudio Bernardi (Contributor), Kristina Fant (Contributor), Dagmar Jirova (Contributor), Tuula Heinonen (Contributor), Marisa Meloni (Contributor), Emma Pedersen (Contributor), Jeroen Rijk (Contributor), Ad Peijnenburg (Contributor), Hilda Witters (Contributor), Ana Palmeira Oliveira (Contributor), Maciej Stepnik (Contributor), Andreas Georg Weber (Contributor), Gerard Bowe (Contributor), Thomas Cole (Contributor), Roman Liska (Contributor), Ingrid Langezaal (Contributor), Robert Landsiedel (Contributor), Yoran Weide (Contributor), Jochem Louisse (Contributor), Antonio de la Vieja Escolar (Contributor), Monica Vaccari (Contributor), Riccardo Villa (Contributor), Andrea Cacciamali (Contributor), Maria Sampieri (Contributor), Chiara Romano (Contributor), Claudia Piutti (Contributor), Valentina Saibene (Contributor), Daniele Pezzetta (Contributor), Marketa Dvorakova (Contributor), Lada Belastova (Contributor), Laura Ceriotti (Contributor), Elisa Carviola (Contributor), An Jacobsen (Contributor), Joanna Roszak (Contributor), Kornelia Kowalczyk (Contributor), Johannes de Lange (Contributor), Aude Kienzler (Contributor) & Sandra Coecke (Contributor)
23 Aug 2021 → 2 Sep 2021Activity: Talk or presentation › Oral presentation › Academic
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Bioassay-directed analysis approach for the identification of relevant pyrrolizidine alkaloids
Ad Peijnenburg (Speaker)
30 Sep 2020Activity: Talk or presentation › Oral presentation › Academic
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Determination of genotoxic potencies of pyrrolizidine alkaloids in HepaRG cells using the γH2AX assay
A.A.C.M. Peijnenburg (Speaker)
12 Sep 2018Activity: Talk or presentation › Oral presentation › Other
Press / Media
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An alternative to testing on mice
1/10/21 → 2/10/21
2 Media contributions
Press/Media: Research › Professional
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EU22005 Partnership for the Assessment of Risk of Chemicals (PARC) (BO-64-101-012)
1/01/22 → 31/12/22
Project: EZproject
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Combinational Toxicology irt complexe producten (KB-37-002-003, KB-23-002-011, KB-15-003-026)
1/01/14 → 31/12/22
Project: EZproject