Ad Peijnenburg

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12 Similar Researchers

bis(tri-n-butyltin)oxide Medicine & Life Sciences

T-cells Chemical Compounds

Genes Chemical Compounds

Assays Chemical Compounds

Jurkat Cells Medicine & Life Sciences

Pyrrolizidine Alkaloids Medicine & Life Sciences

Liver Medicine & Life Sciences

T-Lymphocytes Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1999 2019

1 Citation (Scopus)

Determination of genotoxic potencies of pyrrolizidine alkaloids in HepaRG cells using the γH2AX assay

Louisse, J., Rijkers, D., Stoopen, G., Holleboom, W. J., Delagrange, M., Molthof, E., Mulder, P. P. J., Hoogenboom, R. L. A. P., Audebert, M. & Peijnenburg, A. A. C. M., 1 Sep 2019, In : Food and Chemical Toxicology. 131, 110532.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Pyrrolizidine Alkaloids

pyrrolizidine alkaloids

Assays

assays

riddelliine

Novel strategies for risk assessment of pyrrolizidine alkaloids

Chen, L., 2019, Wageningen: Wageningen University. 245 p.

Research output: Thesis › internal PhD, WU › Academic

Open Access

Predicting estrogen receptor binding of chemicals using a suite of in silico methods – Complementary approaches of (Q)SAR, molecular docking and molecular dynamics

Cotterill, J. V., Palazzolo, L., Ridgway, C., Price, N., Rorije, E., Moretto, A., Peijnenburg, A. & Eberini, I., 1 Sep 2019, In : Toxicology and Applied Pharmacology. 378, 114630.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Molecular Dynamics Simulation

Estrogen Receptors

Computer Simulation

Molecular dynamics

Binding energy

Prediction of in vivo genotoxicity of lasiocarpine and riddelliine in rat liver using a combined in vitro-physiologically based kinetic modelling-facilitated reverse dosimetry approach

Chen, L., Peijnenburg, A., de Haan, L. & Rietjens, I. M. C. M., Aug 2019, In : Archives of Toxicology. 93, 8, p. 2385-2395

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Pyrrolizidine Alkaloids

Liver

Dosimetry

Rats

Kinetics

1 Citation (Scopus)

Quantitative in vitro-to-in vivo extrapolation (QIVIVE) of estrogenic and anti-androgenic potencies of BPA and BADGE analogues

Punt, A., Aartse, A., Bovee, T. F. H., Gerssen, A., van Leeuwen, S. P. J., Hoogenboom, R. L. A. P. & Peijnenburg, A. A. C. M., Jul 2019, In : Archives of Toxicology. 93, 7, p. 1941-1953

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Extrapolation

polycarbonate

Monomers

Availability

Detoxification

Datasets

Fxr-deficiency in mouse liver slices aggravates cyclosporin A toxicity by upregulation of pro-inflammatory genes and downregulation of genes involved in mitochondrial functions

Szalowska, E. (Creator), Pronk, T. (Creator), Peijnenburg, A. (Creator), RIKILT Wageningen UR, 22 Oct 2015

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE63457

Dataset

Model steatogenic compounds (amiodarone, valproic acid, and tetracycline) alter lipid metabolism by different mechanisms in mouse liver slices [Cholestatic compounds exposures]

Szalowska, E. (Creator), van der Burg, B. (Creator), Man, H. (Creator), Hendriksen, P. (Creator), Peijnenburg, A. (Creator), RIKILT Wageningen UR, 23 Dec 2013

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE51544

Dataset

Model steatogenic compounds (amiodarone, valproic acid, and tetracycline) alter lipid metabolism by different mechanisms in mouse liver slices [Necrotic compounds exposures]

Szalowska, E. (Creator), van der Burg, B. (Creator), Man, H. (Creator), Hendriksen, P. (Creator), Peijnenburg, A. (Creator), RIKILT Wageningen UR, 23 Dec 2013

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE51542

Dataset

Expression data from human Jurkat T cells exposed to 31 compounds

Shao, J. (Creator), Katika, M. R. (Creator), Schmeits, P. C. (Creator), Hendriksen, P. (Creator), van Loveren, H. (Creator), Peijnenburg, A. (Creator), Volger, O. (Creator), Rikilt - Institute of Food Safety, 22 Jul 2013

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE46909

Dataset

Model steatogenic compounds (amiodarone, valproic acid, and tetracycline) alter lipid metabolism by different mechanisms in mouse liver slices [Steatogenic compounds exposures]

Szalowska, E. (Creator), van der Burg, B. (Creator), Man, H. (Creator), Hendriksen, P. (Creator), Peijnenburg, A. (Creator), RIKILT Wageningen UR, 23 Dec 2013

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE51543

Dataset