Research output per year
Research output per year
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Dive into the research topics where Ad Peijnenburg is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Determination of in vitro hepatotoxic potencies of a series of perfluoroalkyl substances (PFASs) based on gene expression changes in HepaRG liver cells
Louisse, J., Fragki, S., Rijkers, D., Janssen, A., van Dijk, B., Leenders, L., Staats, M., Bokkers, B., Zeilmaker, M., Piersma, A., Luijten, M., Hoogenboom, R. & Peijnenburg, A., 3 Mar 2023, In: Archives of Toxicology. 97, 4, p. 1113-1131Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
New approach methodologies: A quantitative in vitro to in vivo extrapolation case study with PFASs
Fragki, S., Louisse, J., Bokkers, B., Luijten, M., Peijnenburg, A., Rijkers, D., Piersma, A. H. & Zeilmaker, M. J., Feb 2023, In: Food and Chemical Toxicology. 172, 113559.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
Perfluoroalkyl substances (PFASs) decrease the expression of recombination-activating genes (RAG1 and RAG2) in human B lymphoma Namalwa cells
Janssen, A. W. F., Louisse, J., Rijkers, D., Pinckaers, N. E. T., Hoekstra, S. A., Hoogenboom, R. L. A. P., Peijnenburg, A. A. C. M. & Beekmann, K., Feb 2023, In: Archives of Toxicology. 97, 2, p. 457-468Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Bioassay-directed analysis-based identification of relevant pyrrolizidine alkaloids
Louisse, J., Mulder, P. P. J., Gerssen, A., Stoopen, G., Rijkers, D., van de Schans, M. G. M. & Peijnenburg, A. A. C. M., Aug 2022, In: Archives of Toxicology. 96, 8, p. 2299-2317 19 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus) -
In vitro relative potencies of perfluoroalkyl substances (PFASs) based on gene expression changes in human HepaRG liver cells
Louisse, J., Fragki, S. S., Rijkers, D. E. M. C., Janssen, A. W. F., Staats, M., Zeilmaker, M. J., Piersma, A. H., Luijten, M., Hoogenboom, L. A. P. & Peijnenburg, A. A. C. M., 24 May 2022. 1 p.Research output: Contribution to conference › Poster › Academic
Open Access
Datasets
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Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?
Fragki, S. S. (Creator), Dirven, H. (Creator), Fletcher, T. (Creator), Grasl-Kraupp, B. (Creator), Bjerve Gützkow, K. (Creator), Hoogenboom, R. (Creator), Kersten, S. (Creator), Lindeman, B. (Creator), Louisse, J. (Creator), Peijnenburg, A. (Creator), Piersma, A. H. (Creator), Princen, H. M. G. (Creator), Uhl, M. (Creator), Westerhout, J. (Creator), Zeilmaker, M. J. (Creator) & Luijten, M. (Creator), National Institute for Public Health and the Environment (RIVM), 23 Apr 2021
DOI: 10.6084/m9.figshare.14420432
Dataset
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Expression data from human Jurkat T cells exposed to 31 compounds
Shao, J. (Creator), Katika, M. R. (Creator), Schmeits, P. C. (Creator), Hendriksen, P. (Creator), van Loveren, H. (Creator), Peijnenburg, A. (Creator) & Volger, O. (Creator), Rikilt - Institute of Food Safety, 22 Jul 2013
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE46909
Dataset
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Fxr-deficiency in mouse liver slices aggravates cyclosporin A toxicity by upregulation of pro-inflammatory genes and downregulation of genes involved in mitochondrial functions
Szalowska, E. (Creator), Pronk, T. (Creator) & Peijnenburg, A. (Creator), RIKILT Wageningen UR, 22 Oct 2015
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE63457
Dataset
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Model steatogenic compounds (amiodarone, valproic acid, and tetracycline) alter lipid metabolism by different mechanisms in mouse liver slices [Steatogenic compounds exposures]
Szalowska, E. (Creator), van der Burg, B. (Creator), Man, H. (Creator), Hendriksen, P. (Creator) & Peijnenburg, A. (Creator), RIKILT Wageningen UR, 23 Dec 2013
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE51543
Dataset
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Model steatogenic compounds (amiodarone, valproic acid, and tetracycline) alter lipid metabolism by different mechanisms in mouse liver slices [Necrotic compounds exposures]
Szalowska, E. (Creator), van der Burg, B. (Creator), Man, H. (Creator), Hendriksen, P. (Creator) & Peijnenburg, A. (Creator), RIKILT Wageningen UR, 23 Dec 2013
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE51542
Dataset
Activities
- 5 Oral presentation
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WURlive 14: Minder proefdieren, maar hoe?
Ad Peijnenburg (Speaker) & Katharina Kardinal-Janke (Speaker)
12 Oct 2021Activity: Talk or presentation › Oral presentation › Professional
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European network of high-quality laboratories assessing efficiently the relevance of fully animal-free thyroid mechanistic methods
Barbara Birk (Speaker), Toine Bovee (Contributor), Laureano Cuevas Beltran (Contributor), Flavio Cinato (Contributor), Annamaria Colacci (Contributor), Silvia Dotti (Contributor), Claudio Bernardi (Contributor), Kristina Fant (Contributor), Dagmar Jirova (Contributor), Tuula Heinonen (Contributor), Marisa Meloni (Contributor), Emma Pedersen (Contributor), Jeroen Rijk (Contributor), Ad Peijnenburg (Contributor), Hilda Witters (Contributor), Ana Palmeira Oliveira (Contributor), Maciej Stepnik (Contributor), Andreas Georg Weber (Contributor), Gerard Bowe (Contributor), Thomas Cole (Contributor), Roman Liska (Contributor), Ingrid Langezaal (Contributor), Robert Landsiedel (Contributor), Yoran Weide (Contributor), Jochem Louisse (Contributor), Antonio de la Vieja Escolar (Contributor), Monica Vaccari (Contributor), Riccardo Villa (Contributor), Andrea Cacciamali (Contributor), Maria Sampieri (Contributor), Chiara Romano (Contributor), Claudia Piutti (Contributor), Valentina Saibene (Contributor), Daniele Pezzetta (Contributor), Marketa Dvorakova (Contributor), Lada Belastova (Contributor), Laura Ceriotti (Contributor), Elisa Carviola (Contributor), An Jacobsen (Contributor), Joanna Roszak (Contributor), Kornelia Kowalczyk (Contributor), Johannes de Lange (Contributor), Aude Kienzler (Contributor) & Sandra Coecke (Contributor)
23 Aug 2021 → 2 Sept 2021Activity: Talk or presentation › Oral presentation › Academic
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In vitro-in silico-based assessment of species differences in kinetics: towards harmonization of in vitro clearance studies
Jochem Louisse (Speaker), Nicole Pinckaers (Contributor), Sandra Coecke (Contributor), Ad Peijnenburg (Contributor) & Ans Punt (Contributor)
23 Aug 2021 → 2 Sept 2021Activity: Talk or presentation › Oral presentation › Academic
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Bioassay-directed analysis approach for the identification of relevant pyrrolizidine alkaloids
Ad Peijnenburg (Speaker)
30 Sep 2020Activity: Talk or presentation › Oral presentation › Academic
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Determination of genotoxic potencies of pyrrolizidine alkaloids in HepaRG cells using the γH2AX assay
A.A.C.M. Peijnenburg (Speaker)
12 Sept 2018Activity: Talk or presentation › Oral presentation › Other
Press/Media
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An alternative to testing on mice
1/10/21 → 2/10/21
2 Media contributions
Press/Media: Research › Professional
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EU22005 Partnership for the Assessment of Risk of Chemicals (PARC) (BO-64-101-012)
1/01/22 → 31/12/23
Project: EZproject
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