Research output per year
Research output per year
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Dive into the research topics where Aafke Janssen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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An integrated in vitro and in silico testing strategy applied to PFAS inhibition of antibody production to define a tolerable daily intake
Iulini, M., Janssen, A. W. F., Beekmann, K., Russo, G., Pappalardo, F., Fragki, S., Paini, A. & Corsini, E., Feb 2026, In: Toxicology Letters. 416, 111817.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Mechanistic insights into PFAS-induced effects on B lymphocyte activation and antibody secretion
Iulini, M., Beekmann, K., Hoogenboom, R. L. A. P., Galbiati, V., Russo, G., Pappalardo, F., Fragki, S., Paini, A., Corsini, E. & Janssen, A. W. F., 2026, In: Archives of Toxicology. 100, 7, p. 3073-3090Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
New approach methodologies (NAMs) to support regulatory assessment of developmental immunotoxicity – a new PARC project
Smith, N. M., de Bruijn, V. M. P., Vandebriel, R. J., Hargitai, R., Lumniczky, K., Janssen, A. W. F., Beekmann, K., Usta, B., Tigges, J., Spruck, C., Hurem, S., Iulini, M., Corsini, E., Bado-Nilles, A., Beaudouin, R., Katsiadaki, I., Cano, I., Sebire, M., Ayuk, H. S. & Stojanovska, V. & 11 others, , 17 Apr 2026, In: Frontiers in Toxicology. 8Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Link opens in a new tab Citation (Scopus) -
Pro-inflammatory response of human iPSC-derived intestinal epithelial monolayers towards microbial toxins LPS and nigericin
Aalderink, G., Brouwer, H., Wang, J., Janssen, A. W. F., van der Zande, M., Govers, C., Hoppenbrouwers, T., Bouwmeester, H. & Busch, M., 2026, In: Archives of Toxicology. 100, 2, p. 695-708Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Link opens in a new tab Citations (Scopus) -
In vitro approaches to investigate the effect of chemicals on antibody production: the case study of PFASs
Iulini, M., Bettinsoli, V., Maddalon, A., Galbiati, V., Janssen, A. W. F., Beekmann, K., Russo, G., Pappalardo, F., Fragki, S., Paini, A. & Corsini, E., 2025, In: Archives of Toxicology. 99, 5, p. 2075-2086 12 p., 107734.Research output: Contribution to journal › Article › Academic › peer-review
Open Access11 Link opens in a new tab Citations (Scopus)
Datasets
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Gene expression profiling in human precision-cut liver slices upon treatment with the FXR agonist obeticholic acid [human]
IJssennagger, N. (Creator), Janssen, A. (Creator), van Mil, S. (Creator) & Kersten, S. (Creator), Wageningen University, 27 Jan 2016
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE76161
Dataset
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The impact of PPARα activation on whole genome gene expression in human precision-cut liver slices
Janssen, A. (Creator), Bretzel, B. (Creator), Stoopen, G. (Creator), Berends, F. J. (Creator), Janssen, I. M. (Creator), Peijnenburg, A. (Creator) & Kersten, S. (Creator), Wageningen University, 23 Nov 2015
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE71731
Dataset
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EFSA Project on the use of NAMs to explore the immunotoxicity of PFAS (Annexes B, C, D1, E, G, I, K, M, O)
Corsini, E. (Creator), Iulini, M. (Creator), Galbiati, V. (Creator), Maddalon, A. (Creator), Pappalardo, F. (Creator), Russo, G. (Creator), Hoogenboom, R. (Creator), Beekmann, K. (Creator), Janssen, A. (Creator), Louisse, J. (Creator), Fragki, S. S. (Creator) & Paini, A. (Creator), European Food Safety Authority, 23 Aug 2024
Dataset
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Gene expression profiling in human precision-cut liver slices upon treatment with the FXR agonist obeticholic acid [mouse]
IJssennagger, N. (Creator), Janssen, A. (Creator), Kersten, S. (Creator) & van Mil, S. W. C. (Creator), Wageningen University, 27 Jan 2016
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE76162
Dataset
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Gene expression profiling in human precision-cut liver slices upon treatment with the FXR agonist obeticholic acid
IJssenagger, N. (Creator), Janssen, A. W. F. (Creator), Kersten, A. H. (Creator) & van Mil, S. W. C. (Creator), Wageningen University, 27 Jan 2016
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE76163
Dataset
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Add_Validatie en acceptatie van volledig diervrije proefdiervrije innovaties binnen voedselveiligheid (fiche) (BO-43-227-008)
Janssen, A. (Project Leader)
1/01/26 → 31/12/26
Project: LVVN project
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Accelerating the transition towards alternatives to animal trials: from molecule to animal (KB-54-000-006)
Janssen, A. (Project Leader)
1/01/25 → 31/12/28
Project: LVVN project
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Toxicologische karakterisering van stoffen en mengsels m.b.v. proefdiervervangende methoden (WOT-02-001-066, WOT-02-002-003, WOT-02-002-017)
Janssen, A. (Project Leader)
1/01/08 → 31/12/26
Project: LVVN project
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In vitro models for immunotoxicity (KB-56-002-020)
Janssen, A. (Project Leader)
1/01/25 → 31/12/25
Project: LVVN project
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EFSA NAMs PFAS immunotox (KB-37-002-041)
Janssen, A. (Project Leader)
1/01/22 → 31/12/23
Project: LVVN project