Research output per year
Research output per year
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Dive into the research topics where Aafke Janssen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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In vitro approaches to investigate the effect of chemicals on antibody production: the case study of PFASs
Iulini, M., Bettinsoli, V., Maddalon, A., Galbiati, V., Janssen, A. W. F., Beekmann, K., Russo, G., Pappalardo, F., Fragki, S., Paini, A. & Corsini, E., 2025, In: Archives of Toxicology. 99, 5, p. 2075-2086 12 p., 107734.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
Comparison of iPSC-derived human intestinal epithelial cells with Caco-2 cells and human in vivo data after exposure to Lactiplantibacillus plantarum WCFS1
Janssen, A. W. F., van der Lugt, B., Duivenvoorde, L. P. M., Vos, A. P., Bastiaan-Net, S., Tomassen, M. M. M., Verbokkem, J. A. C., Blok-Heimerikx, E., Hooiveld, G. J. E. J., van Baarlen, P., Ferrier, L. & van der Zande, M., 2 Nov 2024, In: Scientific Reports. 14, 26464.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Determination of in vitro immunotoxic potencies of a series of perfluoralkylsubstances (PFASs) in human Namalwa B lymphocyte and human Jurkat T lymphocyte cells
Janssen, A. W. F., Jansen Holleboom, W., Rijkers, D., Louisse, J., Hoekstra, S. A., Schild, S., Vrolijk, M. F., Hoogenboom, R. L. A. P. & Beekmann, K., 14 Mar 2024, In: Frontiers in Toxicology. 6, 1347965.Research output: Contribution to journal › Article › Academic › peer-review
Open Access2 Citations (Scopus) -
Development and application of an immunocompetent human induced pluripotent stem cell-derived intestinal epithelial cell model for hazard assessment of the oral exposure route
van der Zande, M., Duivenvoorde, L. P. M., Fabrizi, B., Vos, A. P., Bastiaan-Net, S., Tomassen, M. M. M. & Janssen, A. W. F., 10 Mar 2024.Research output: Contribution to conference › Poster › Academic
Open Access -
EFSA Project on the use of NAMs to explore the immunotoxicity of PFAS
Corsini, E., Iulini, M., Galbiati, V., Maddalon, A., Pappalardo, F., Russo, G., Hoogenboom, R. L. A. P., Beekmann, K., Janssen, A. W. F., Louisse, J., Fragki, S. & Paini, A., Aug 2024, In: EFSA Supporting Publications. 21, 8, 8926E.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Datasets
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Gene expression profiling in human precision-cut liver slices upon treatment with the FXR agonist obeticholic acid [human]
IJssennagger, N. (Creator), Janssen, A. (Creator), van Mil, S. (Creator) & Kersten, S. (Creator), Wageningen University, 27 Jan 2016
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE76161
Dataset
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Differential gene expression in iPSC-derived human intestinal epithelial cell layers following exposure to two concentrations of the Short Chain Fatty Acids butyrate, propionate and acetate
Grouls, M. (Creator), Janssen, A. W. F. (Creator), Duivenvoorde, L. P. M. (Creator), Hooiveld, G. J. E. J. (Creator), Bouwmeester, H. (Creator) & van der Zande, M. (Creator), Wageningen University & Research, 6 Apr 2022
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE200309
Dataset
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The impact of PPARα activation on whole genome gene expression in human precision-cut liver slices
Janssen, A. (Creator), Bretzel, B. (Creator), Stoopen, G. (Creator), Berends, F. J. (Creator), Janssen, I. M. (Creator), Peijnenburg, A. (Creator) & Kersten, S. (Creator), Wageningen University, 23 Nov 2015
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE71731
Dataset
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Transcriptional profilling of liver from C57BL/6 wildtype and PPARα-knockout mice treated with PFOA and GenX after 20 weeks of high-fat diet
Attema, B. (Creator), Janssen, A. W. F. (Creator), Rijkers, D. (Creator), van Schothorst, E. M. (Creator), Hooiveld, G. J. E. J. (Creator) & Kersten, S. (Creator), Wageningen University & Research, 30 Aug 2022
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE212294
Dataset
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Transport of perfluoroalkyl substances across human induced pluripotent stem cell-derived intestinal epithelial cells in comparison with primary human intestinal epithelial cells and Caco-2 cells
Janssen, A. W. F. (Creator), Duivenvoorde, L. P. M. (Creator), Beekmann, K. (Creator), Pinckaers, N. (Creator), van der Hee, B. (Creator), Noorlander, A. (Creator), Leenders, L. L. (Creator), Louisse, J. (Creator) & van der Zande, M. (Creator), Wageningen University & Research, 29 May 2024
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE268603
Dataset
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Accelerating the transition towards alternatives to animal trials: from molecule to animal (KB-54-000-006)
Janssen, A. (Project Leader)
1/01/25 → 31/12/28
Project: LVVN project
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In vitro models for immunotoxicity (KB-56-002-020)
Janssen, A. (Project Leader)
1/01/25 → 31/12/25
Project: LVVN project
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EFSA NAMs PFAS immunotox (KB-37-002-041)
Janssen, A. (Project Leader)
1/01/22 → 31/12/23
Project: LVVN project
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The role of gut microbiota and chronic inflammation as drivers of cardiovascular disease.
Janssen, A. (PhD candidate) & Kersten, S. (Promotor)
1/10/13 → 1/12/17
Project: PhD