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Aafke Janssen, PhD

    20132020

    Research output per year

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    Fingerprint Dive into the research topics where Aafke Janssen is active. These topic labels come from the works of this person. Together they form a unique fingerprint. If staff member(s) published prior to his/her WUR affiliation, it is possible that the publication overview, Fingerprint and network diagram are incomplete.

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    Research Output

    • 8 Article
    • 1 internal PhD, WU

    Perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), and perfluorononanoic acid (PFNA) increase triglyceride levels and decrease cholesterogenic gene expression in human HepaRG liver cells

    Louisse, J., Rijkers, D., Stoopen, G., Janssen, A., Staats, M., Hoogenboom, R., Kersten, S. & Peijnenburg, A., 25 Jun 2020, In : Archives of Toxicology. 19 p.

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access

    • Loss of angiopoietin-like 4 (ANGPTL4) in mice with diet-induced obesity uncouples visceral obesity from glucose intolerance partly via the gut microbiota

    Janssen, A. W. F., Katiraei, S., Bartosinska, B., Eberhard, D., Willems van Dijk, K. & Kersten, S., Jun 2018, In : Diabetologia. 61, 6, p. 1447-1458

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    • 15 Citations (Scopus)

    ANGPTL4 promotes bile acid absorption during taurocholic acid supplementation via a mechanism dependent on the gut microbiota

    Janssen, A. W. F., Dijk, W., Boekhorst, J., Kuipers, F., Groen, A. K., Lukovac, S., Hooiveld, G. J. E. J. & Kersten, S., 2017, In : Biochimica et Biophysica Acta. Molecular and Cell Biology of Lipids. 1862, 10, p. 1056-1067

    Research output: Contribution to journal › Article › Academic › peer-review

    • 8 Citations (Scopus)

    Investigation into mediators of metabolic health: A role for the gut microbiota, bile acids and Angptl4

    Janssen, A. W. F., 2017, Wageningen: Wageningen University. 306 p.

    Research output: Thesis › internal PhD, WU

    Open Access

    • Modulation of the gut microbiota impacts nonalcoholic fatty liver disease: a potential role for bile acids

    Janssen, A. W. F., Houben, T., Katiraei, S., Dijk, W., Boutens, L., van der Bolt, N., Wang, Z., Brown, J. M., Hazen, S. L., Mandard, S., Shiri-Sverdlov, R., Kuipers, F., Willems van Dijk, K., Vervoort, J., Stienstra, R., Hooiveld, G. J. E. J. & Kersten, S., 2017, In : Journal of Lipid Research. 58, 7, p. 1399-1416

    Research output: Contribution to journal › Article › Academic › peer-review

    • 35 Citations (Scopus)

    Datasets

    The impact of PPARα activation on whole genome gene expression in human precision-cut liver slices

    Janssen, A. (Creator), Bretzel, B. (Creator), Stoopen, G. (Creator), Berends, F. J. (Creator), Janssen, I. M. (Creator), Peijnenburg, A. (Creator) & Kersten, S. (Creator), Wageningen University, 23 Nov 2015

    https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE71731

    Dataset

    Gene expression profiling in human precision-cut liver slices upon treatment with the FXR agonist obeticholic acid

    IJssenagger, N. (Creator), Janssen, A. (Creator), Kersten, S. (Creator) & van Mil, S. W. C. (Creator), Wageningen University, 27 Jan 2016

    https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE76163

    Dataset

    Gene expression profiling in human precision-cut liver slices upon treatment with the FXR agonist obeticholic acid [human]

    IJssennagger, N. (Creator), Janssen, A. (Creator), van Mil, S. (Creator) & Kersten, S. (Creator), Wageningen University, 27 Jan 2016

    https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE76161

    Dataset

    Gene expression profiling in human precision-cut liver slices upon treatment with the FXR agonist obeticholic acid [mouse]

    IJssennagger, N. (Creator), Janssen, A. (Creator), Kersten, S. (Creator) & van Mil, S. W. C. (Creator), Wageningen University, 27 Jan 2016

    https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE76162

    Dataset

    Modulating the gut microbiota by dietary guar gum protects against diet-induced obesity but promotes non-alcoholic steatohepatitis in mice

    Janssen, A. (Creator), Houben, T. (Creator), Katiraei, S. (Creator), Boutens, L. (Creator), van der Bolt, N. (Creator), Wang, Z. (Creator), Brown, J. M. (Creator), Hazen, S. L. (Creator), Shiri-Sverdlov, R. (Creator), Willems van Dijk, K. (Creator), Vervoort, J. (Creator), Stienstra, R. (Creator), Hooiveld, G. (Creator) & Kersten, S. (Creator), Wageningen University, 6 Jun 2017

    https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE76087

    Dataset

    Projects

    The role of gut microbiota and chronic inflammation as drivers of cardiovascular disease.

    Janssen, A. & Kersten, S.

    1/10/13 → 1/12/17

    Project: PhD