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Aafke Janssen, PhD

    20132018
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    Fingerprint Dive into the research topics where Aafke Janssen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

    • 45 Similar Researchers
    Bile Acids and Salts Medicine & Life Sciences
    guar gum Medicine & Life Sciences
    Liver Medicine & Life Sciences
    Obesity Medicine & Life Sciences
    Health Medicine & Life Sciences
    Taurocholic Acid Medicine & Life Sciences
    Peroxisome Proliferator-Activated Receptors Medicine & Life Sciences
    Angiopoietins Medicine & Life Sciences

    Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Research Output 2015 2018

    • 7 Article
    • 1 internal PhD, WU
    9 Citations (Scopus)

    Loss of angiopoietin-like 4 (ANGPTL4) in mice with diet-induced obesity uncouples visceral obesity from glucose intolerance partly via the gut microbiota

    Janssen, A. W. F., Katiraei, S., Bartosinska, B., Eberhard, D., Willems van Dijk, K. & Kersten, S., Jun 2018, In : Diabetologia. 61, 6, p. 1447-1458

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    Glucose Intolerance
    Abdominal Obesity
    Obesity
    Diet
    Intra-Abdominal Fat
    4 Citations (Scopus)

    ANGPTL4 promotes bile acid absorption during taurocholic acid supplementation via a mechanism dependent on the gut microbiota

    Janssen, A. W. F., Dijk, W., Boekhorst, J., Kuipers, F., Groen, A. K., Lukovac, S., Hooiveld, G. J. E. J. & Kersten, S., 2017, In : Biochimica et Biophysica Acta. Molecular and Cell Biology of Lipids. 1862, 10, p. 1056-1067

    Research output: Contribution to journal › Article › Academic › peer-review

    Taurocholic Acid
    Bile Acids and Salts
    Triglycerides
    Gastrointestinal Microbiome
    angiopoietin 4

    Investigation into mediators of metabolic health: A role for the gut microbiota, bile acids and Angptl4

    Janssen, A. W. F., 2017, Wageningen: Wageningen University. 306 p.

    Research output: Thesis › internal PhD, WU › Academic

    Open Access
    Angiopoietins
    Bile Acids and Salts
    Health
    Liver
    Proteins
    24 Citations (Scopus)

    Modulation of the gut microbiota impacts nonalcoholic fatty liver disease: a potential role for bile acids

    Janssen, A. W. F., Houben, T., Katiraei, S., Dijk, W., Boutens, L., van der Bolt, N., Wang, Z., Brown, J. M., Hazen, S. L., Mandard, S., Shiri-Sverdlov, R., Kuipers, F., Willems van Dijk, K., Vervoort, J., Stienstra, R., Hooiveld, G. J. E. J. & Kersten, S., 2017, In : Journal of Lipid Research. 58, 7, p. 1399-1416

    Research output: Contribution to journal › Article › Academic › peer-review

    guar gum
    Bile Acids and Salts
    Liver
    Modulation
    Inflammation
    23 Citations (Scopus)

    Potential mediators linking gut bacteria to metabolic health: A critical view

    Janssen, A. W. F. & Kersten, S., 2017, In : Journal of Physiology. 595, 2, p. 477-487

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    Bacteria
    Insulin Resistance
    Adipose Tissue
    Health
    Obesity

    Datasets

    The impact of PPARα activation on whole genome gene expression in human precision-cut liver slices

    Janssen, A. (Creator), Bretzel, B. (Creator), Stoopen, G. (Creator), Berends, F. J. (Creator), Janssen, I. M. (Creator), Peijnenburg, A. (Creator), Kersten, S. (Creator), Wageningen University, 23 Nov 2015

    https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE71731

    Dataset

    Gene expression profiling in human precision-cut liver slices upon treatment with the FXR agonist obeticholic acid [human]

    IJssennagger, N. (Creator), Janssen, A. (Creator), van Mil, S. (Creator), Kersten, S. (Creator), Wageningen University, 27 Jan 2016

    https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE76161

    Dataset

    Gene expression profiling in human precision-cut liver slices upon treatment with the FXR agonist obeticholic acid [mouse]

    IJssennagger, N. (Creator), Janssen, A. (Creator), Kersten, S. (Creator), van Mil, S. W. C. (Creator), Wageningen University, 27 Jan 2016

    https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE76162

    Dataset

    Modulating the gut microbiota by dietary guar gum protects against diet-induced obesity but promotes non-alcoholic steatohepatitis in mice

    Janssen, A. (Creator), Houben, T. (Creator), Katiraei, S. (Creator), Boutens, L. (Creator), van der Bolt, N. (Creator), Wang, Z. (Creator), Brown, J. M. (Creator), Hazen, S. L. (Creator), Shiri-Sverdlov, R. (Creator), Willems van Dijk, K. (Creator), Vervoort, J. (Creator), Stienstra, R. (Creator), Hooiveld, G. (Creator), Kersten, S. (Creator), Wageningen University, 6 Jun 2017

    https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE76087

    Dataset

    Gene expression profiling in human precision-cut liver slices upon treatment with the FXR agonist obeticholic acid

    IJssenagger, N. (Creator), Janssen, A. (Creator), Kersten, S. (Creator), van Mil, S. W. C. (Creator), Wageningen University, 27 Jan 2016

    https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE76163

    Dataset

    Projects 2013 2017

    The role of gut microbiota and chronic inflammation as drivers of cardiovascular disease.

    Janssen, A. & Kersten, S.

    1/10/13 → 1/12/17

    Project: PhD