Research Output 1976 2020

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Abstract
2016

Variability in quercetin action

van Schothorst, E. M., Bunschoten, J. E., van der Stelt, I., Hollman, P. C. H., Rietjens, I. M. C. M. & Keijer, J., 13 Sep 2016.

Research output: Contribution to conferenceAbstractAcademic

2014

Assuring safety without animal testing concept (ASAT). Integration of human disease data with in vitro data to improve toxicology testing

Stierum, R., Aarts, J. M. M. J. G., Boorsma, J., Bosgra, S., Caiment, F., Ezendam, J., Greuping, R., Hendriksen, P., Soeteman-Hernandez, L. G., Jennen, D., Kleinjans, J., Kroese, D., Kuper, F., van Loveren, H., Monshouwer, M., Russel, F., van Someren, E., Tsamou, M. & Groothuis, G., 2014, In : Toxicology Letters. 229, suppl.10, p. S4-S21

Research output: Contribution to journalAbstractAcademic

Toxicology
Animals
Knowledge Bases
Safety
Dermatitis

Effects of Sodium and Potassium Supplementation on Blood Pressure and Arterial Stiffness in Untreated (Pre)Hypertensives

Gijsbers, L., Dower, J. I., Mensink, M. R. & Geleijnse, J. M., 2014.

Research output: Contribution to conferenceAbstractAcademic

Open Access
Sodium-Restricted Diet
Vascular Stiffness
Potassium
Sodium
Blood Pressure
2013

Harmonizing the Land Cover Classification System (LCCS) and the General Habitat Categories (GHC) taxonomies

Kosmidou, V., Petrou, Z., Adamo, P., Manakos, I., Mücher, C. A., Lucas, R., Blonda, P., Jongman, R. H. G., Bogers, M., Tomaselli, V., Tarantino, C. & Bunce, R. G. H., 2013.

Research output: Contribution to conferenceAbstractAcademic

In vitro pituitary and thyroid cell proliferation assays and their relevance as alternatives to animal testing

Jomaa, B., Aarts, M. M. J. G., de Haan, L. H. J., Peijnenburg, A. A. C. M., Bovee, T. F. H., Murk, A. J. & Rietjens, I. M. C. M., 2013, Book of Abstracts of the 49th Congress of the European Societies of Toxicology (EUROTOX). Roberts, R. (ed.). Vol. 221. p. S151-S151

Research output: Chapter in Book/Report/Conference proceedingAbstract

Animal Testing Alternatives
Thyroid Gland
Cell Proliferation
Thyroid Hormone Receptors
Weights and Measures

LiDAR data enhances the BIOSOS biodiversity monitoring approach

Mücher, C. A., Lucas, R., Blonda, P., Kramer, H., Roupioz, L. F. S., Jongman, R. H. G., Kosmidou, V., Wolters, M. F., Padoa-Schioppa, E., Bogers, M., Haveman, R., Nagendra, H., Tomaselli, V. & Adamo, M., 2013.

Research output: Contribution to conferenceAbstractAcademic

Quercetin induces hepatic lipid omega-oxidation and lowers serum lipid levels in mice

Hoek-van den Hil, E. F., Keijer, J., Bunschoten, A., Vervoort, J. J. M., Stankova, B., Bekkenkamp, M., Herreman, L., Venema, D. P., Hollman, P. C. H., Tvrzicka, E., Rietjens, I. & van Schothorst, E. M., 2013, Annals of Nutrition & Metabolism : Abstracts of the 20th International Congress of Nutrition. Munich: Karger, Vol. 62. p. 149-149

Research output: Chapter in Book/Report/Conference proceedingAbstract

2011
2010

Effects of fullerene nanoparticles on the soil earthworm Lumbricus rubellus

van der Ploeg, M., van den Brink, N. W., Rietjens, I., Baveco, J. M. & van der Hout, A., 2010, Proceedings of the 20th SETAC Europe congress, Seville, Spain, 23-27 May 2010. Seville, Spain, p. 92

Research output: Chapter in Book/Report/Conference proceedingAbstract

Mushroom compounds differentially affect innate immune responses through monocytes

van de Velde, J., Walczak, A. P. & Schots, A., 2010.

Research output: Contribution to conferenceAbstractAcademic

Open Access
2009

Stereoselective kinetics of R- and S-enantiomers of the citrus flavonoid hesperetin in vitro

Brand, W., Shao, J., Rein, M. J., Barron, D., Williamson, G., van Bladeren, P. J. & Rietjens, I., 2009, In : Drug Metabolism Reviews. 41, S1, p. 83

Research output: Contribution to journalAbstractAcademic

2008

Impact of bioturbation, black carbon and other sediment properties on sediment-to-water fluxes of PCBs, PAHs and PBDEs. A novel flux method to assess chemical mobility

Koelmans, A. A., Oosterhoff, R. T., Jonker, M. T. O., Poot, A., Gillissen, F., Korytar, P., de Lange, H. J. & Schipper, C. A., 2008, SETAC Europe 18th Annual Meeting, 25-29 May 2008, Warsaw, Poland. Brussels: SETAC Europe, p. 53

Research output: Chapter in Book/Report/Conference proceedingAbstract

Release of pollutants from aquatic sediments to overlying waters: implications for Water Framework Directive goals?

de Lange, H. J., Korytar, P., Schipper, C. A., Smedes, F., Koelmans, A. A., Hin, J., Klopstra, E., Maas, H., Harmsen, J. & Joziasse, J., 2008, SETAC Europe 18th Annual Meeting, 25-29 May 2008, Warsaw, Poland. Brussels: SETAC, p. 139

Research output: Chapter in Book/Report/Conference proceedingAbstract

2007

Improvement and development of QSAR's for phenols

Strikwold, M. & Zvinavashe, E., 2007, In : Chemico-Biological Interactions. 169, 2, p. 141

Research output: Contribution to journalAbstractAcademic

Quantitative Structure-Activity Relationship
Phenols
Animals
Availability
Testing

Modulating hesperetin bioavailability at the level of its intestinal metabolism and ABC transporter mediated efflux studied in Caco-2 monolay

Brand, W., van der Wel, P. A. I., Williamson, G. & Rietjens, I., 2007, Abstracts of the Dutch toxicology days, 12th–13th June 2007. Vol. 169. p. 132-133

Research output: Chapter in Book/Report/Conference proceedingAbstract

ATP-Binding Cassette Transporters
Toxicology
Biological Availability
hesperetin

Modulating hesperetin bioavailability at the level of its intestinal metabolism and ABC transporter mediated efflux studied in Caco-2 monolayers

Brand, W., van der Wel, P. A. I., Williamson, G., van Bladeren, P. J. & Rietjens, I., 2007, In : Toxicology Letters. 172, Suppl. 1, p. S101

Research output: Contribution to journalAbstractAcademic

ATP-Binding Cassette Transporters
Metabolism
Biological Availability
Monolayers
hesperetin

Oxidative stress and changed gene expression profiles in fiber-/particle-induced carcinogenesis

Bhattacharya, K., Alink, G. M. & Dopp, E., 2007, In : International Journal of Human Genetics. 7, 1, p. 1-21 21 p.

Research output: Contribution to journalAbstractAcademic

Open Access

What proportion of the EINECS list compounds can be covered by QSAR models?

Zvinavashe, E., Soffers, A. E. M. F., Murk, A. J., Vervoort, J. J. M., Freidig, A. & Rietjens, I. M. C. M., 2007, In : Chemico-Biological Interactions. 169, 2, p. 143

Research output: Contribution to journalAbstractAcademic

Quantitative Structure-Activity Relationship
Toxicity
Nitrobenzenes
Animals
United States Environmental Protection Agency
2006

Activation of cancer protective enzymes by flavonoids

Lee, Y. Y., Boerboom, A. M. J. F., Martin, A. H., van Berkel, W. J. H., Rietjens, I. M. C. M. & Aarts, J. M. M. J. G., 2006, Abstracts of the Dutch toxicology days, 13th-14th June 2006. Vol. 161. p. 170

Research output: Chapter in Book/Report/Conference proceedingAbstract

Advanced marine lipophilic toxins in shellfish analysis using UPLC-ToF-MS

Gerssen, A., van Rhijn, J. A. & de Boer, J., 2006, In : Chemico-Biological Interactions. 161, 2, p. 166

Research output: Contribution to journalAbstractAcademic

An in vitro and in silico study on the flavonoid mediated modulation of the transport of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) through Caco-2 monolayers

Schutte, M. E., Freidig, A., van de Sandt, J. J. M., Alink, G. M., Rietjens, I. M. C. M. & Groten, J. P., 2006, Abstracts of the Dutch toxicology days, 13th-14th June 2006. Vol. 161. p. 173

Research output: Chapter in Book/Report/Conference proceedingAbstract

A PBTK model for estragole metabolism in rat and human to improve the carcinogenic risk assessment of doses relevant to dietary human exposures

Punt, A., Freidig, A., Delatour, T., Scholz, G., Schilter, B., van Bladeren, P. J. & Rietjens, I. M. C. M., 2006, Abstracts of the Dutch toxicology days, 13th-14th June 2006. Vol. 161. p. 172

Research output: Chapter in Book/Report/Conference proceedingAbstract

Assessment of the health-promoting activity of flavonoids for the application in food

Lee-Hilz, Y. Y., Boerboom, A. M. J. F., Westphal, A. H., van Berkel, W. J. H., Rietjens, I. M. C. M. & Aarts, J. M. M. J. G., 2006.

Research output: Contribution to conferenceAbstractAcademic

Bioactivation of the herb-based carcinogens methyleugenol and estragole and modulation by other herbal ingredients

Jeurissen, S. M. F., Alink, G. M., Sudhölter, E. J. R., Cnubben, N. H. P., van Beek, T. A. & Rietjens, I. M. C. M., 2006, Abstracts of the Dutch toxicology days, 13th-14th June 2006. Vol. 161. p. 168

Research output: Chapter in Book/Report/Conference proceedingAbstract

Development of toxicity tests for submerged macrophytes

Arts, G. H. P., Belgers, J. D. M. & Hoekzema, C. C., 2006, Controversies and solutions in environmental sciences; abstract book SETAC Europe 16th annual meeting. Brussels (Belgium): SETAC, p. 246

Research output: Chapter in Book/Report/Conference proceedingAbstract

Glutathione-dependent transport of heavy metal compounds by multidrug resistance proteins MRP1 and MRP2

Cnubben, N. H. P., Balvers, M. G. J., Usta, M., van Zanden, J. J., van Bladeren, P. J., Rietjens, I. & Wortelboer, H. M., 2006, In : Toxicology Letters. 164, S1, p. S199-S199

Research output: Contribution to journalAbstractAcademic

In vitro bioassays to quantify toxic potencies of (environmental mixtures) of compounds - Applications and Advantages

Gutleb, A. C. & Murk, A. J., 2006.

Research output: Contribution to conferenceAbstractAcademic

Mechanism of flavonoid-induced EPRE-mediated gene transcription

Lee-Hilz, Y. Y., Boerboom, A. M. J. F., Westphal, A. H., van Berkel, W. J. H., Rietjens, I. M. C. M. & Aarts, J. M. M. J. G., 2006.

Research output: Contribution to conferenceAbstractAcademic

Modulation and modelling of flavonoid bioavailability at the level of its intestinal metabolism and transport

Brand, W., Williamson, G., van Bladeren, P. J. & Rietjens, I. M. C. M., 2006, Abstracts of the Dutch toxicology days, 13th-14th June 2006. Vol. 161. p. 165

Research output: Chapter in Book/Report/Conference proceedingAbstract

Multi-species tool for modeling acute toxicity of substituted mononitrobenzenes in aquatic systems

Zvinavashe, E., Murk, A. J., Vervoort, J. J. M., Soffers, A. E. M. F., Freidig, A. & Rietjens, I. M. C. M., 2006, Abstracts of the Dutch toxicology days, 13th-14th June 2006. Vol. 161. p. 175

Research output: Chapter in Book/Report/Conference proceedingAbstract

Profiling of gene expression modulation in human lymphocytes is not a sensitive biomarker for exposure to AH receptor agonists

Waard, P., Hoogenboom, L. A. P., Peijnenburg, A., Aarts, J. M. M. J. G., de Kok, T. & van Schooten, F. J., 2006, Abstracts of the Dutch toxicology days, 13th-14th June 2006. Vol. 161. p. 174 (3)-175 (1)

Research output: Chapter in Book/Report/Conference proceedingAbstract

Selective estrogenicity in orally exposed transgenic male mice of compounds known to be estrogenic in vitro

ter Veld, M. G. R., van der Saag, P. T., Rietjens, I. M. C. M. & Murk, A. J., 2006, Abstracts of the Dutch toxicology days, 13th-14th June 2006. Vol. 161. p. 174 (1)

Research output: Chapter in Book/Report/Conference proceedingAbstract

Luciferases
Transgenic Mice
Liver
Dichlorodiphenyl Dichloroethylene
Kidney
2005

Cruciferous Vegetable Consumption, Glutathione-S-Transferase Polymorphisms, and Colorectal Adenoma Risk in a Dutch Case-Control Study

Tijhuis, M. J., Wark, P. A., Aarts, J. M. M. J. G., Visker, M. H. P. W., Nagengast, F. M., Kok, F. J. & Kampman, E., Dec 2005, In : The Journal of Nutrition. 135, 12, p. 3044S-3044S

Research output: Contribution to journalAbstractAcademic

Glutathione Transferase
Vegetables
Adenoma
Case-Control Studies
Genotype
2001

Effects of persistent organic pollutants (POPs) on reproduction in fish eating birds

de Roode, D. F. & Bosveld, A. T. C., 2001, Proceedings from the 11th SETAC-Europe Congress, Madrid, 2001. p. 164

Research output: Chapter in Book/Report/Conference proceedingAbstract

2000

A novel in vivo assay for (xeno-)estrogens using transgenic zebrafish

Legler, J., Broekhof, J. L. M., Lanser, P. H., Brouwer, A., Vethaak, A. D., Murk, A. J. & van der Burg, B. J., 2000, Proceedings of Society of Environmental Toxicology and Chemistry : Third SETAC World Congress, Brighton, 2000. - Brighton : [s.n.], 2000. p. np 03:A3

Research output: Chapter in Book/Report/Conference proceedingAbstract

Dutch national investigation on estrogenic compounds in the aquatic environment (LOES) : first results

Vethaak, A. D., Ruiter, H., Belfroid, A. C., de Boer, J., Bulder, A. S., Grinwis, G., Lahr, J., Legler, J., Murk, A. J., van de Velde, E. & de Voogt, P., 2000, Proceedings of Society of Environmental Toxicology and Chemistry : Third SETAC World Congress, Brighton 2000. - Brighton : [s.n.], 2000. p. np 03:A3

Research output: Chapter in Book/Report/Conference proceedingAbstract

Estrogenic potency of mixtures of (xeno)estrogens in several Dutch environmental compartments. Research in the framework of the Dutch National Investigation on Estrogenic Compounds in the Aquatic Environment (LOES)

Murk, A. J., Legler, J., Spenkelink, A., de Boer, J., de Voogt, P., Jol, J. & Vethaak, A. D., 2000, Proceedings of Society of Environmental Toxicology and Chemistry : Third SETAC World Congress, Brighton 2000. - Brighton : [s.n.], 2000. p. np 03:A3

Research output: Chapter in Book/Report/Conference proceedingAbstract

Estrogen receptor expression and transactivation in transgenic zebrafish

Legler, J., Broekhof, J. L. M., Brouwer, A., Murk, A. J., Vethaak, A. D. & van der Burg, B., 2000, Proceedings of Society of Environmental Toxicology and Chemistry : Third SETAC World Congress, Brighton 2000. - Brighton : [s.n.], 2000. p. np 03:A3

Research output: Chapter in Book/Report/Conference proceedingAbstract

In vitro estrogenic potency of polybrominated diphenyl ethers

Hoving, S., Meerts, I. A. T. M., Letcher, E., Bergman, A., van der Burg, B. & Brouwer, A., 2000, In : The Toxicologist. 54, 1, p. 238

Research output: Contribution to journalAbstractAcademic

In vitro thyroidogenic estrogenic and dioxin-like activity of polybrominated diphenyl ethers (PBDEs)

Meerts, I. A. T. M., Letcher, R., Hoving, S., van Leeuwen-Bol, I., Luijks, E. A. C., Bergman, A. & Brouwer, A., 2000, SETAC Congres 2000. - [S.l..] : [s.n.], 2000. p. np 03:A1

Research output: Chapter in Book/Report/Conference proceedingAbstract

Pure PCB metabolites cross the placenta in the rat and may reduce fetal thyroid hormone levels

Meerts, I. A. T. M., Assink, Y., Cenijn, P. H., Weijers, B. M., Bergman, A., Koeman, J. H. & Brouwer, A., 2000, In : The Toxicologist. 54, 1, p. 261

Research output: Contribution to journalAbstractAcademic

1999

Application of 3 in vitro bioassays for estrogenicity in some Dutch waste water treatment plants and large rivers : research in the framework of national pilot study on estrogenic compounds (LOES)

Murk, A. J., Belfroid, A. C., Meerman, J., Legler, J., Schafer, A. J., Rijs, G. & Vethaak, A. D., 1999, Congress Proceedings, Environmental Endocrine Disrupting Chemicals, Ascona, Switzerland, March 1999 / Walter Giger, Karl Fent, Urs Friederich (eds). p. 41

Research output: Chapter in Book/Report/Conference proceedingAbstract

Development of transgenic zebrafish for in vivo assessment of estrogenic compounds

Legler, J., Broekhof, J., Brouwer, A., Lanser, P., Murk, A. J., Vethaak, A. D. & van der Burg, B., 1999, Congress Proceedings, 20th Annual Meetiung Society of Environmental Toxicology and Chemistry (SETAC) : Sustaining global environmental integrity, Philadelphia, Pennsylvania, USA, November 1999. - SETAC : Penascola, Florida, 1999. - ISBN 1087-8939(no editors). p. 60

Research output: Chapter in Book/Report/Conference proceedingAbstract

Embryotoxicity of pesticides to chicken embryonic development - thiamine homeostasis as a biomarker

de Roode, D. & Bosveld, A. T. C., 1999, Congress Proceedings, Quality of life and environment in cultured landscapes, 9th Annual Meeting of SETAC Europe, 25 - 29 May 1999, Leipzig, Germany. p. 122

Research output: Chapter in Book/Report/Conference proceedingAbstract

In vitro and in vivo assessment of potential (anti-)estrogenic compounds using stably transfected cell lines and transgenic zebrafish

Legler, J., van den Brink, C. E., Broekhof, J., Brouwer, A., Murk, A. J., van der Saag, P., Vethaak, A. D. & van der Burg, B., 1999, Congress Proceedings / Keystone Symposia on molecular en cellular biology : Endocrine Disruptors. Lake Tahoe, California,January 1999 / Kenneth S.Korach and George M.Stancel (eds). p. 33

Research output: Chapter in Book/Report/Conference proceedingAbstract

In vitro and in vivo assessment of potential (anti-)estrogenic compounds with a stably transfected cell line and transgenic zebrafish

Legler, J., van den Brink, C. E., Broekhof, J., Brouwer, A., Murk, A. J., van der Saag, P., Vethaak, A. D. & van der Burg, B., 1999, Congress Proceedings, Environmental Endocrine Disrupting Chemicals, Ascona, Zwitzerland, March 1999 / Walter Giger, KarlFent, Urs Friederich (eds). p. 37

Research output: Chapter in Book/Report/Conference proceedingAbstract

1998

Adapted amphibian test demonstrates long-term effects of early exposure to PCB126 on Xenopus lavis not visible in any early life stage test (FETAX)

Gutleb, A. C., Appelman, J., Bronkhorst, M., van den Berg, J. H. J. & Murk, A. J., 1998, Congress Proceedings/Society of Environmental Toxicology and Chemistry, Charlotte, NC, USA, November 1998. p. 222

Research output: Chapter in Book/Report/Conference proceedingAbstract

Development, validation and application of a highly responsive reporter gene assay for estrogenic and anti-estrogenic compounds

Legler, J., van der Burg, B., Vethaak, A. D., Brouwer, A. & Murk, A. J., 1998, Congress Proceedings/Society of Environmental Toxicology and Chemistry, Charlotte, NC, USA, November 1998. p. 150

Research output: Chapter in Book/Report/Conference proceedingAbstract