Research Output 2016 2019

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Article
2019
3 Citations (Scopus)

Extending the linear-noise approximation to biochemical systems influenced by intrinsic noise and slow lognormally distributed extrinsic noise

Keizer, E. M., Bastian, B., Smith, R. W., Grima, R. & Fleck, C., 28 May 2019, In : Physical Review E. 99, 5, 052417.

Research output: Contribution to journalArticleAcademicpeer-review

Biochemical Networks
Approximation
approximation
Molecules
Exact Simulation
11 Citations (Scopus)

Optogenetic control shows that kinetic proofreading regulates the activity of the T cell receptor

Yousefi, O. S., Günther, M., Hörner, M., Chalupsky, J., Wess, M., Brandl, S. M., Smith, R. W., Fleck, C., Kunkel, T., Zurbriggen, M. D., Höfer, T., Weber, W. & Schamel, W. W. A., 5 Apr 2019, In : eLife. 8

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Optogenetics
T-Cell Antigen Receptor
Ligands
Kinetics
Phytochrome B
3 Citations (Scopus)

Phytochrome B dynamics departs from photoequilibrium in the field

Sellaro, R., Smith, R. W., Legris, M., Fleck, C. & Casal, J. J., Feb 2019, In : Plant Cell and Environment. 42, 2, p. 606-617

Research output: Contribution to journalArticleAcademicpeer-review

Phytochrome B
phytochrome
Light
shade
Phytochrome
2018
1 Citation (Scopus)

DMPy: a Python package for automated mathematical model construction of large-scale metabolic systems

Smith, R. W., van Rosmalen, R. P., Martins dos Santos, V. A. P. & Fleck, C., 19 Jun 2018, In : BMC Systems Biology. 12, 72.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Boidae
Python
Metabolic Networks and Pathways
Theoretical Models
Mathematical Model
1 Citation (Scopus)

Insight into nuclear body formation of phytochromes through stochastic modelling and experiment

Grima, R., Sonntag, S., Venezia, F., Kircher, S., Smith, R. W. & Fleck, C., 18 May 2018, In : Physical Biology. 15, 5, 056003.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Phytochrome B
Phytochrome
Plant Photoreceptors
Plant Proteins
Light
2017
6 Citations (Scopus)

Interactions Between phyB and PIF Proteins Alter Thermal Reversion Reactions in vitro

Smith, R. W., Helwig, B., Westphal, A. H., Pel, E., Borst, J. W. & Fleck, C., 1 Nov 2017, In : Photochemistry and Photobiology. 93, 6, p. 1525-1531

Research output: Contribution to journalArticleAcademicpeer-review

Phytochrome B
phytochrome
Hot Temperature
proteins
Light
8 Citations (Scopus)

Safety evaluation of substituted thiophenes used as flavoring ingredients

Cohen, S. M., Fukushima, S., Gooderham, N. J., Guengerich, F. P., Hecht, S. S., Rietjens, I. M. C. M., Smith, R. L., Bastaki, M., Harman, C. L., McGowen, M. M., Valerio, L. G. & Taylor, S. V., 2017, In : Food and Chemical Toxicology. 99, p. 40-59

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
thiophenes
Thiophenes
flavorings
Metabolism
ingredients
2016
1 Citation (Scopus)

FEMA expert panel review of p-mentha-1,8-dien-7-al genotoxicity testing results

Cohen, S. M., Fukushima, S., Gooderham, N. J., Guengerich, F. P., Hecht, S. S., Rietjens, I. M. C. M., Smith, R. L., Bastaki, M., Harman, C. L., McGowen, M. M. & Taylor, S. V., 2016, In : Food and Chemical Toxicology. 98, p. 201-209

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Mentha
Flavors
genotoxicity
Assays
Micronucleus Tests
10 Citations (Scopus)

Unearthing the transition rates between photoreceptor conformers

Smith, R. W., Helwig, B., Westphal, A. H., Pel, E., Hörner, M., Beyer, H. M., Samodelov, S. L., Weber, W., Zurbriggen, M. D., Borst, J. & Fleck, C., 2016, In : BMC Systems Biology. 10, 1, 110.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Optogenetics
Phytochrome
Cross section
Dimerization
Hot Temperature