Research Output 1954 2020

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2020

Postnatal induction of muscle fatty acid oxidation in mice differing in propensity to obesity: a role of pyruvate dehydrogenase

Buresova, J., Janovska, P., Kuda, O., Krizova, J., Romijnders van der Stelt, I., Keijer, J., Hansikova, H., Rossmeisl, M. & Kopecky, J., Jan 2020, In : International Journal of Obesity. 44, p. 235–244

Research output: Contribution to journalArticleAcademicpeer-review

Pyruvic Acid
Oxidoreductases
AMP-Activated Protein Kinases
Fatty Acids
Obesity
2019

A Lowly Digestible-Starch Diet after Weaning Enhances Exogenous Glucose Oxidation Rate in Female, but Not in Male, Mice

Fernández-Calleja, J. M. S., Bouwman, L. M. S., Swarts, H. J. M., Billecke, N., Oosting, A., Keijer, J. & van Schothorst, E. M., 18 Sep 2019, In : Nutrients. 11, 9, 2242.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Weaning
Starch
weaning
starch
oxidation
Open Access
Volatile Organic Compounds
nutritional intervention
volatile organic compounds
dairies
Fats
6 Citations (Scopus)

Biomarkers of Nutrition and Health: New Tools for New Approaches

Picó, C., Serra, F., Rodríguez, A. M., Keijer, J. & Palou, A., 16 May 2019, In : Nutrients. 11, 5

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
biomarkers
Biomarkers
nutrition
Food
food intake

Cold Induced Depot-Specific Browning in Ferret Aortic Perivascular Adipose Tissue

Reynés, B., van Schothorst, E. M., Keijer, J., Ceresi, E., Oliver, P. & Palou, A., 18 Sep 2019, In : Frontiers in Physiology. 10, 1171.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Ferrets
Adipose Tissue
Thorax
Subcutaneous Fat
White Adipose Tissue
1 Citation (Scopus)

Combined Treatment with L-Carnitine and Nicotinamide Riboside Improves Hepatic Metabolism and Attenuates Obesity and Liver Steatosis

Salic, K., Gart, E., Seidel, F., Verschuren, L., Caspers, M., van Duyvenvoorde, W., Wong, K. E., Keijer, J., Bobeldijk-Pastorova, I., Wielinga, P. Y. & Kleemann, R., 5 Sep 2019, In : International Journal of Molecular Sciences. 20, 18

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
carnitine
obesity
nicotinamide
Carnitine
fats
7 Citations (Scopus)

Comparison of bovine milk fat and vegetable fat for infant formula: Implications for infant health

Hageman, J. H. J., Danielsen, M., Nieuwenhuizen, A. G., Feitsma, A. L. & Dalsgaard, T. K., 1 May 2019, In : International Dairy Journal. 92, p. 37-49

Research output: Contribution to journalArticleAcademicpeer-review

plant fats
Infant Formula
infant formulas
Vegetables
milk fat

Consequences of negative energy balance on follicular development and oocyte quality in primiparous sows

Costermans, N. G. J., Teerds, K. J., Middelkoop, A., Roelen, B. A. J., Schoevers, E. J., van Tol, H. T. A., Laurenssen, B. F. A., Koopmanschap, R. E., Zhao, Y., Blokland, M., van Tricht, E. F., Zak, L. J., Keijer, J., Kemp, B. & Soede, N. M., 2 Sep 2019, In : Biology of Reproduction. p. 1-11

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Lactation
Oocytes
Somatomedins
Mental Competency
Steroids

Determinants of vitamin D status in physically active elderly in the Netherlands

ten Haaf, D. S. M., Balvers, M. G. J., Timmers, S., Eijsvogels, T. M. H., Hopman, M. T. E. & Klein Gunnewiek, J. M. T., Dec 2019, In : European Journal of Nutrition. 58, 8, p. 3121–3128

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Vitamin D
Netherlands
Exercise
Life Style
Linear Models
4 Citations (Scopus)

Diet-independent correlations between bacteria and dysfunction of gut, adipose tissue, and liver: A comprehensive microbiota analysis in feces and mucosa of the ileum and colon in obese mice with NAFLD

Gart, E., Lima, E. S., Schuren, F., de Ruiter, C. G. F., Attema, J., Verschuren, L., Keijer, J., Salic, K., Morrison, M. C. & Kleemann, R., 1 Jan 2019, In : International Journal of Molecular Sciences. 20, 1, 1.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
feces
adipose tissues
Obese Mice
diets
Microbiota

Effects of cold exposure revealed by global transcriptomic analysis in ferret peripheral blood mononuclear cells

Reynés, B., van Schothorst, E. M., Keijer, J., Palou, A. & Oliver, P., 1 Dec 2019, In : Scientific Reports. 9, 1, 19985.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Ferrets
Blood Cells
Acclimatization
Rodentia
Genes
1 Citation (Scopus)

Extended indirect calorimetry with isotopic CO2 sensors for prolonged and continuous quantification of exogenous vs. total substrate oxidation in mice

Fernández-Calleja, J. M. S., Bouwman, L. M. S., Swarts, H. J. M., Oosting, A., Keijer, J. & van Schothorst, E. M., 8 Aug 2019, In : Scientific Reports. 9, 11507.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
calorimetry
carbon dioxide
oxidation
palmitates
mice
4 Citations (Scopus)

Feeding mitochondria: Potential role of nutritional components to improve critical illness convalescence

Wesselink, E., Koekkoek, W. A. C., Grefte, S., Witkamp, R. F. & van Zanten, A. R. H., Jun 2019, In : Clinical Nutrition. 38, 3, p. 982-995

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
coenzyme Q10
Micronutrients
Critical Illness
Mitochondria
Selenium

Feed intake of the sow and playful creep feeding of piglets influence piglet behaviour and performance before and after weaning

Middelkoop, A., Costermans, N., Kemp, B. & Bolhuis, J. E., 1 Dec 2019, In : Scientific Reports. 9, 1, 16140.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Weaning
Ear
Growth
Exploratory Behavior
Drinking
3 Citations (Scopus)

Follicular development of sows at weaning in relation to estimated breeding value for within-litter variation in piglet birth weight

Costermans, N. G. J., Teerds, K. J., Keijer, J., Knol, E. F., Koopmanschap, R. E., Kemp, B. & Soede, N. M., Mar 2019, In : Animal. 13, 3, p. 554-563

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
follicular development
breeding value
litters (young animals)
birth weight
sows
1 Citation (Scopus)

Free fatty acid release from vegetable and bovine milk fat-based infant formulas and human milk during two-phase in vitro digestion

Hageman, J. H. J., Keijer, J., Dalsgaard, T. K., Zeper, L. W., Carrière, F., Feitsma, A. L. & Nieuwenhuizen, A. G., 1 Apr 2019, In : Food and Function. 10, 4, p. 2102-2113 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Infant Formula
in vitro digestion
infant formulas
Human Milk
breast milk

High dose of dietary nicotinamide riboside induces glucose intolerance and white adipose tissue dysfunction in mice fed a mildly obesogenic diet

Shi, W., Hegeman, M. A., Doncheva, A., Bekkenkamp-Grovenstein, M., de Boer, V. C. J. & Keijer, J., 1 Oct 2019, In : Nutrients. 11, 10, 2439.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
White Adipose Tissue
nicotinamide
white adipose tissue
Glucose Intolerance
Diet
Granulosa Cells
Ovary
Angiopoietin-1
Somatomedins
Cell Proliferation
Open Access
Near-Infrared Spectroscopy
Exercise
Quadriceps Muscle
Muscles
Reperfusion
Open Access
Near-Infrared Spectroscopy
Oxygen Consumption
Muscles
Population
Mitochondria

Maturation of white adipose tissue function in C57BL/6j mice from weaning to young adulthood

Kodde, A., Engels, E., Oosting, A., van Limpt, K., van der Beek, E. & Keijer, J., 9 Jul 2019, In : Frontiers in Physiology. 10, 14 p., 836.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
White Adipose Tissue
Weaning
Inbred C57BL Mouse
Groin
Citrate (si)-Synthase
2 Citations (Scopus)

Mito-nuclear communication by mitochondrial metabolites and its regulation by B-vitamins

Janssen, J. J. E., Grefte, S., Keijer, J. & De Boer, V. C. J., 12 Feb 2019, In : Frontiers in Physiology. 10, FEB, 78.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Vitamin B Complex
Mitochondria
Communication
Metabolic Networks and Pathways
Organelles

Partial replacement of glucose by galactose in the post-weaning diet improves parameters of hepatic health

Bouwman, L. M. S., Swarts, H. J. M., Fernández-Calleja, J. M. S., van der Stelt, I., Schols, H., Oosting, A., Keijer, J. & van Schothorst, E. M., Nov 2019, In : Journal of Nutritional Biochemistry. 73, 108223.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Nutrition
Weaning
Galactose
Health
Diet

Plasma citrulline concentration, a marker for intestinal functionality, reflects exercise intensity in healthy young men

Kartaram, S., Mensink, M., Teunis, M., Schoen, E., Witte, G., Janssen Duijghuijsen, L., Verschuren, M., Mohrmann, K., M'Rabet, L., Knipping, K., Wittink, H., van Helvoort, A., Garssen, J., Witkamp, R., Pieters, R. & van Norren, K., Oct 2019, In : Clinical Nutrition. 38, 5, p. 2251-2258 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Citrulline
Glutamine
Exercise
Workload
Amino Acids

Primary human testicular PDGFRα+ cells are multipotent and can be differentiated into cells with Leydig cell characteristics in vitro

Eliveld, J., van den Berg, E. A., Chikhovskaya, J. V., van Daalen, S. K. M., de Winter-Korver, C. M., van der Veen, F., Repping, S., Teerds, K. & van Pelt, A. M. M., 29 Sep 2019, In : Human Reproduction. 34, 9, p. 1621-1631 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Leydig Cells
Testosterone
Testis
LH Receptors
Rodentia
2 Citations (Scopus)

Replacing Part of Glucose with Galactose in the Postweaning Diet Protects Female But Not Male Mice from High-Fat Diet-Induced Adiposity in Later Life

Bouwman, L. M. S., Fernández-Calleja, J. M. S., van der Stelt, I., Oosting, A., Keijer, J. & van Schothorst, E. M., 1 Jul 2019, In : The Journal of Nutrition. 149, 7, p. 1140-1148 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Adiposity
High Fat Diet
Galactose
Diet
Glucose

Sex-Specific Differences in Fat Storage, Development of Non-Alcoholic Fatty Liver Disease and Brain Structure in Juvenile HFD-Induced Obese Ldlr-/-.Leiden Mice

Jacobs, S. A. H., Gart, E., Vreeken, D., Franx, B. A. A., Wekking, L., Verweij, V. G. M., Worms, N., Schoemaker, M. H., Gross, G., Morrison, M. C., Kleemann, R., Arnoldussen, I. A. C. & Kiliaan, A. J., 10 Aug 2019, In : Nutrients. 11, 8

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
fatty liver
High Fat Diet
high fat diet
Sex Characteristics
Fats

Steroid profile of porcine follicular fluid and blood serum: Relation with follicular development

Costermans, N. G. J., Soede, N. M., Blokland, M. H., van Tricht, E. F., Keijer, J., Kemp, B. & Teerds, K. J., 27 Dec 2019, In : Physiological Reports. 7, 24, e14320.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Follicular Fluid
Swine
Steroids
Follicular Phase
Serum
4 Citations (Scopus)

Symposium 2: Nutrient interactions and their role in protection from chronic diseases: β-Carotene in the human body: Metabolic bioactivation pathways - From digestion to tissue distribution and excretion

Bohn, T., Desmarchelier, C., El, S. N., Keijer, J., Van Schothorst, E., Rühl, R. & Borel, P., 1 Feb 2019, In : Proceedings of the Nutrition Society. 78, 1, p. 68-87

Research output: Contribution to journalArticleAcademicpeer-review

Tissue Distribution
Carotenoids
Metabolic Networks and Pathways
Human Body
Digestion
4 Citations (Scopus)

The MemTrax Test Compared to the Montreal Cognitive Assessment Estimation of Mild Cognitive Impairment

Van Der Hoek, M. D., Nieuwenhuizen, A., Keijer, J. & Ashford, J. W., 12 Feb 2019, In : Journal of Alzheimer's Disease. 67, 3, p. 1045-1054 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Cognition
Cognitive Dysfunction
Dementia
Linear Models
Outcome Assessment (Health Care)

Transcriptional Response of White Adipose Tissue to Withdrawal of Vitamin B3

Shi, W., Hegeman, M. A., Doncheva, A., van der Stelt, I., Bekkenkamp‐Grovenstein, M., van Schothorst, E. M., Brenner, C., Boer, V. C. J. & Keijer, J., 16 Apr 2019, In : Molecular Nutrition & Food Research. e1801100.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
White Adipose Tissue
white adipose tissue
Niacinamide
niacin
Avitaminosis
1 Citation (Scopus)

Treatment of Severe Protein Malnutrition After Bariatric Surgery

Kuin, C., den Ouden, F., Brandts, H., Deden, L., Hazebroek, E., van Borren, M. & de Boer, H., Oct 2019, In : Obesity Surgery. 29, 10, p. 3095-3102

Research output: Contribution to journalArticleAcademicpeer-review

Bariatrics
Hypoalbuminemia
Bariatric Surgery
Nose
Serum Albumin
8 Citations (Scopus)

What is the best housing temperature to translate mouse experiments to humans?

Keijer, J., Li, M. & Speakman, J. R., Jul 2019, In : Molecular Metabolism. 25, p. 168-176

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Temperature
Inbred C57BL Mouse
Energy Metabolism
Controlled Environment
Body Size

White Adipose Tissue Response of Obese Mice to Ambient Oxygen Restriction at Thermoneutrality: Response Markers Identified, but no WAT Inflammation

Hoevenaars, F. P. M., Keijer, J., van der Stelt, I., Duivenvoorde, L. P. M., Herreman, L., van Nes, R., Friedecký, D., Hegeman, M. A. & Van Schothorst, E. M., 10 May 2019, In : Genes. 10, 5, 359.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Obese Mice
White Adipose Tissue
Oxygen
Inflammation
Adiponectin
2018
1 Citation (Scopus)
Open Access
Enterocytes
Fatty Acids
Lipids
Dietary Carbohydrates
Mitochondrial Proteins
2 Citations (Scopus)

Arthrospira (Spirulina) platensis supplementation affects folliculogenesis, progesterone and ghrelin levels in fattening pre-pubertal gilts

Abadjieva, D., Nedeva, R., Marchev, Y., Jordanova, G., Chervenkov, M., Dineva, J., Shimkus, A., Shimkiene, A., Teerds, K. & Kistanova, E., Feb 2018, In : Journal of Applied Phycology. 30, 1, p. 445-452 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Arthrospira
Spirulina platensis
ghrelin
follicular development
gilts
3 Citations (Scopus)

BAFF augments IgA2 and IL-10 production by TLR7/8 stimulated total peripheral blood B cells

den Hartog, C. G., van Osch, T. L. J., Vos, M., Meijer, B., Savelkoul, H. F. J., van Neerven, R. J. J. & Brugman, S., 9 Feb 2018, In : European journal of immunology. 48, 2, p. 283-292

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Interleukin-10
Immunoglobulin A
Blood Cells
B-Lymphocytes
Virus Diseases
3 Citations (Scopus)

Direct and Long-Term Metabolic Consequences of Lowly vs. Highly-Digestible Starch in the Early Post-Weaning Diet of Mice

Fernández-Calleja, J. M. S., Bouwman, L. M. S., Swarts, H. J. M., Oosting, A., Keijer, J. & van Schothorst, E. M., 17 Nov 2018, In : Nutrients. 10, 11, 1788.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Weaning
Starch
weaning
starch
Diet
1 Citation (Scopus)
Carnitine Acyltransferases
Choline
Transferases
Protein Isoforms
Carnitine O-Acetyltransferase
4 Citations (Scopus)

Insulin sensitivity linked skeletal muscle Nr4a1 DNA methylation is programmed by the maternal diet and modulated by voluntary exercise in mice

Kasch, J., Kanzleiter, I., Saussenthaler, S., Schürmann, A., Keijer, J., van Schothorst, E., Klaus, S. & Schumann, S., 21 Mar 2018, In : Journal of Nutritional Biochemistry. 57, p. 86-92

Research output: Contribution to journalArticleAcademicpeer-review

DNA Methylation
Nutrition
Muscle
Insulin Resistance
Skeletal Muscle
4 Citations (Scopus)

Maternal circulating vitamin status and colostrum vitamin composition in healthy lactating women—A systematic approach

de Vries, J. Y., Pundir, S., McKenzie, E., Keijer, J. & Kussmann, M., 1 Jun 2018, In : Nutrients. 10, 6, 687.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Colostrum
colostrum
Vitamins
vitamins
Mothers
8 Citations (Scopus)

Mitochondrial dynamics in cancer-induced cachexia

van der Ende, M., Grefte, S., Plas, R., Meijerink, J., Witkamp, R. F., Keijer, J. & van Norren, K., 1 Dec 2018, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1870, 2, p. 137-150

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Mitochondrial Dynamics
Cachexia
Rodentia
Neoplasms
Mitochondrial Degradation
5 Citations (Scopus)

No Adverse Programming by Post-Weaning Dietary Fructose of Body Weight, Adiposity, Glucose Tolerance, or Metabolic Flexibility

Bouwman, L. M. S., Fernández-Calleja, J. M. S., Swarts, H. J. M., van der Stelt, I., Oosting, A., Keijer, J. & van Schothorst, E. M., 1 Jan 2018, In : Molecular Nutrition and Food Research. 62, 2, 1700315.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Adiposity
adiposity
glucose tolerance
Weaning
Fructose
6 Citations (Scopus)

Non-invasive continuous real-time in vivo analysis of microbial hydrogen production shows adaptation to fermentable carbohydrates in mice

Fernández-Calleja, J. M. S., Konstanti, P., Swarts, H. J. M., Bouwman, L. M. S., Garcia-Campayo, V., Billecke, N., Oosting, A., Smidt, H., Keijer, J. & van Schothorst, E. M., 18 Oct 2018, In : Scientific Reports. 8, 1, 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Hydrogen
Carbohydrates
Diet
Starch
Indirect Calorimetry
8 Citations (Scopus)

Preantral follicular atresia occurs mainly through autophagy, while antral follicles degenerate mostly through apoptosis

Meng, L., Jan, S. Z., Hamer, G., van Pelt, A. M., van der Stelt, I., Keijer, J. & Teerds, K. J., 1 Oct 2018, In : Biology of Reproduction. 99, 4, p. 853-863

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Follicular Atresia
Autophagy
Granulosa Cells
Apoptosis
Ovarian Follicle
7 Citations (Scopus)

Presence of anti-Müllerian hormone (AMH) during follicular development in the porcine ovary

Almeida, F. R. C. L., Costermans, N. G. J., Soede, N. M., Bunschoten, A., Keijer, J., Kemp, B. & Teerds, K. J., 31 Jul 2018, In : PLoS ONE. 13, 7, e0197894.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
follicular development
Ovary
Swine
hormones
Hormones
3 Citations (Scopus)

Supplement use and dietary sources of folate, vitamin D, and n-3 fatty acids during preconception: The GLIMP2 study

Looman, M., van den Berg, C., Geelen, A., Samlal, R. A. K., Heijligenberg, R., Klein Gunnewiek, J. M. T., Balvers, M. G. J., Leendertz-Eggen, C. L., Wijnberger, L. D. E., Feskens, E. J. M. & Brouwer-Brolsma, E. M., 25 Jul 2018, In : Nutrients. 10, 8, 962.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Cholecalciferol
Dietary Supplements
vitamin D
Folic Acid
folic acid
2017
4 Citations (Scopus)

Adaptation of exercise-induced stress in well-trained healthy young men

Janssen Duijghuijsen, L. M., Keijer, J., Mensink, M. R., Lenaerts, K., Ridder, L. O., Nierkens, S., Kartaram, S., Verschuren, M. C. M., Pieters, R., Bas, R., Witkamp, R. F., Wichers, H. J. & van Norren, K., 2017, In : Experimental Physiology. 102, 1, p. 86-99

Research output: Contribution to journalArticleAcademicpeer-review

Exercise
Lactulose
Rhamnose
Energy Metabolism
Urine
6 Citations (Scopus)

Amplification of R-spondin1 signaling induces granulosa cell fate defects and cancers in mouse adult ovary

De Cian, M. C., Pauper, E., Bandiera, R., Vidal, V. P. I., Sacco, S., Gregoire, E. P., Chassot, A. A., Panzolini, C., Wilhelm, D., Pailhoux, E., Youssef, S. A., De Bruin, A., Teerds, K., Schedl, A., Gillot, I. & Chaboissier, M. C., 2017, In : Oncogene. 36, 2, p. 208-218

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Granulosa Cells
Ovary
Granulosa Cell Tumor
Neoplasms
Sex Differentiation
1 Citation (Scopus)

Body weight cycling with identical diet composition does not affect energy balance and has no adverse affect on metabolic health parameters

Palm, I. F., Schram, R., Swarts, J. J. M., van Schothorst, E. M. & Keijer, J., 20 Oct 2017, In : Nutrients. 9, 10, 13 p., 1149.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
weight cycling
energy balance
Body Weight
Diet
body weight