Research Output 2005 2019

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Review article
2019
2 Citations (Scopus)

Renaissance of traditional DNA transfer strategies for improvement of industrial lactic acid bacteria

Bron, P. A., Marcelli, B., Mulder, J., van der Els, S., Morawska, L. P., Kuipers, O. P., Kok, J. & Kleerebezem, M., 1 Apr 2019, In : Current Opinion in Biotechnology. 56, p. 61-68 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Lactic acid
Lactic Acid
Bacteria
DNA
Clustered Regularly Interspaced Short Palindromic Repeats
7 Citations (Scopus)

Understanding mode of action can drive the translational pipeline towards more reliable health benefits for probiotics

Kleerebezem, M., Binda, S., Bron, P. A., Gross, G., Hill, C., van Hylckama Vlieg, J. E. T., Lebeer, S., Satokari, R. & Ouwehand, A. C., 1 Apr 2019, In : Current Opinion in Biotechnology. 56, p. 55-60

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Probiotics
Insurance Benefits
Pipelines
Health
Clinical Trials
2018
14 Citations (Scopus)

Interactions of surface exopolysaccharides from bifidobacteriumand lactobacilluswithin the intestinal environment

Castro-Bravo, N., Wells, J. M., Margolles, A. & Ruas-Madiedo, P., 11 Oct 2018, In : Frontiers in Microbiology. 9, OCT, 2426.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Probiotics
Bifidobacterium
Bacteria
Carbohydrates
Lactobacillus
6 Citations (Scopus)

Lactic acid bacteria for delivery of endogenous or engineered therapeutic molecules

Bron, P. A. & Kleerebezem, M., 3 Aug 2018, In : Frontiers in Microbiology. 9, AUG, 1821.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Lactic Acid
Bacteria
Health
Lactococcus
Genetic Engineering
1 Citation (Scopus)

Microbial metabolic gatekeeping in the jejunum

Kleerebezem, M., 1 Jun 2018, In : Nature Microbiology. 3, 6, p. 650-651

Research output: Contribution to journalReview articleAcademicpeer-review

Gatekeeping
Overnutrition
Microbiota
Jejunum
Malnutrition
2015
30 Citations (Scopus)

Evolutionary engineering to enhance starter culture performance in food fermentations

Bachmann, H., Pronk, J. T., Kleerebezem, M. & Teusink, B., 2015, In : Current Opinion in Biotechnology. 32, p. 1-7

Research output: Contribution to journalReview articleAcademicpeer-review

Starters
Fermentation
Phenotype
Food
Flavors
67 Citations (Scopus)

The small intestine microbiota, nutritional modulation and relevance for health

El Aidy, S. F., van den Bogert, B. & Kleerebezem, M., 2015, In : Current Opinion in Biotechnology. 32, p. 14-20

Research output: Contribution to journalReview articleAcademicpeer-review

Microbiota
Small Intestine
Modulation
Health
Physiology
2014
389 Citations (Scopus)

Intestinal permeability - a new target for disease prevention and therapy

Bischoff, S. C., Barbara, G., Buurman, W., Ockhuizen, T., Schulzke, J. D., Serino, M., Tilg, H., Watson, A. & Wells, J. M., 2014, In : BMC Gastroenterology. 14, 25 p., 189.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Permeability
Therapeutics
Diet
Bacteria
Food
86 Citations (Scopus)

Production of aroma compounds in lactic fermentations

Smid, E. J. & Kleerebezem, M., 2014, In : Annual Review of Food Science and Technology. 5, p. 313-326

Research output: Contribution to journalReview articleAcademicpeer-review

lactic fermentation
odor compounds
Fermentation
Lactic Acid
Milk
81 Citations (Scopus)

The Role of CRISPR-Cas Systems in Virulence of Pathogenic Bacteria

Louwen, R., Staals, R. H. J., Endtz, H. P., van Baarlen, P. & van der Oost, J., 2014, In : Microbiology and Molecular Biology Reviews. 78, 1, p. 74-88

Research output: Contribution to journalReview articleAcademicpeer-review

Clustered Regularly Interspaced Short Palindromic Repeats
Virulence
Bacteria
Archaeal Genome
Interspersed Repetitive Sequences
2013
38 Citations (Scopus)

Cell surface-associated compounds of probiotic lactobacilli sustain the strain-specificity dogma

Bron, P. A., Tomita, S., Mercenier, A. M. E. & Kleerebezem, M., 2013, In : Current Opinion in Microbiology. 16, 3, p. 262-269

Research output: Contribution to journalReview articleAcademicpeer-review

Probiotics
Lactobacillus
Health Status
Pharmacology
Ligands
293 Citations (Scopus)

Faecalibacterium prausnitzii and human intestinal health

Miquel, S., Martin, R., Rossi, O., Bermudez-Humaran, L. G., Chatel, J. M., Sokol, H., Thomas, M., Wells, J. M. & Langella, P., 2013, In : Current Opinion in Microbiology. 16, 3, p. 255-261

Research output: Contribution to journalReview articleAcademicpeer-review

Health
Trinitrobenzenesulfonic Acid
Dysbiosis
Bacteria
Microbiota
72 Citations (Scopus)

Microbiome and skin diseases

Zeeuwen, P. L., Kleerebezem, M., Timmerman, H. M. & Schalkwijk, J., 2013, In : Current Opinion in Allergy and Clinical Immunology. 13, 5, p. 514-520

Research output: Contribution to journalReview articleAcademicpeer-review

Microbiota
Skin Diseases
Skin
Homeostasis
Dysbiosis
5 Citations (Scopus)

Molecular signatures for the dynamic process of establishing intestinal host-microbial homeostasis: potential for disease diagnostics?

El Aidy, S. F. & Kleerebezem, M., 2013, In : Current Opinion in Gastroenterology. 29, 6, p. 621-627

Research output: Contribution to journalReview articleAcademicpeer-review

Molecular Dynamics Simulation
Homeostasis
Dysbiosis
Microbiota
Health Status
16 Citations (Scopus)

Omics approaches to study host-microbiota interactions

van Baarlen, P., Kleerebezem, M. & Wells, J., 2013, In : Current Opinion in Microbiology. 16, 3, p. 270-277

Research output: Contribution to journalReview articleAcademicpeer-review

Microbiota
Germ-Free Life
Metagenomics
Metabolomics
Immune System
141 Citations (Scopus)

Regulation of intestinal homeostasis and immunity with probiotic lactobacilli

van Baarlen, P., Wells, J. & Kleerebezem, M., 2013, In : Trends in Immunology. 34, 5, p. 208-215

Research output: Contribution to journalReview articleAcademicpeer-review

Probiotics
Lactobacillus
Immunity
Microbiota
Homeostasis
45 Citations (Scopus)

The quest for probiotic effector molecules - Unraveling strain specificity at the molecular level

Lee, I. C., Tomita, S., Kleerebezem, M. & Bron, P. A., 2013, In : Pharmacological Research. 69, 1, p. 61-74

Research output: Contribution to journalReview articleAcademicpeer-review

Probiotics
Peptidoglycan
Lactobacillus
Genomics
Teichoic Acids
21 Citations (Scopus)

Types of cell death and methods of their detection in yeast Saccharomyces cerevisiae

Wloch-Salamon, D. M. & Bem, A. E., 2013, In : Journal of Applied Microbiology. 114, 2, p. 287-298

Research output: Contribution to journalReview articleAcademicpeer-review

Saccharomyces cerevisiae
Cell Death
Yeasts
Autophagy
Metabolic Networks and Pathways
2012
300 Citations (Scopus)

Emerging molecular insights into the interaction between probiotics and the host intestinal mucosa

Bron, P. A., van Baarlen, P. & Kleerebezem, M., 2012, In : Nature Reviews Microbiology. 10, p. 66-78

Research output: Contribution to journalReview articleAcademicpeer-review

Probiotics
Intestinal Mucosa
Nutrigenomics
Health
Bacteria
2011
53 Citations (Scopus)

Recombinant lactic acid bacteria as mucosal biotherapeutic agents

Daniel, C., Roussel, Y., Kleerebezem, M. & Pot, B., 2011, In : Trends in Biotechnology. 29, 10, p. 499-508

Research output: Contribution to journalReview articleAcademicpeer-review

Lactic acid
Lactic Acid
Bacteria
Gastrointestinal Tract
Health
420 Citations (Scopus)

Regulation of Tight Junction Permeability by Intestinal Bacteria and Dietary Components

Ulluwishewa, D., Anderson, R. C., McNabb, W. C., Moughan, P. J., Wells, J. & Roy, N. C., 2011, In : The Journal of Nutrition. 141, 5, p. 769-776

Research output: Contribution to journalReview articleAcademicpeer-review

Tight Junction Proteins
Tight Junctions
Permeability
Bacteria
Myosin-Light-Chain Kinase
2008
358 Citations (Scopus)

Mucosal delivery of therapeutic and prophylactic molecules using lactic acis bacteria

Wells, J. & Mercenier, A. M. E., 2008, In : Nature Reviews Microbiology. 6, 5, p. 349-362

Research output: Contribution to journalReview articleAcademicpeer-review

Lactic Acid
Milk
Bacteria
Antigens
Lactococcus