Research Output 2005 2020

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Article
2010
10 Citations (Scopus)

Alterations in early cytokine-mediated immune responses to Plasmodium falciparum infection in Tanzanian children with mineral element deficiencies: a cross-sectional survey

Mbugi, E. V., Meijerink, M., Veenemans, J., Jeurink, P. V., McCall, M., Olomi, R. M., Shao, J. F., Verhoef, H. & Savelkoul, H. F. J., 2010, In : Malaria Journal. 9, 13 p., 130.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Plasmodium falciparum
Malaria
Minerals
Cross-Sectional Studies
Micronutrients
29 Citations (Scopus)

ApuA, a multifunctional x-glucan-degrading enzyme of Streptococcus suis, mediates adhesion to porcine epithelium and mucus

Ferrando, M. L., Fuentes, S., de Greeff, A., Smith, H. E. & Wells, J., 2010, In : Microbiology. 156, p. 2818-2828

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Streptococcus suis
Glucans
Mucus
Swine
Epithelium
22 Citations (Scopus)

Differential activation of the Toll-like receptor 2/6 complex by lipoproteins of Streptococcus suis serotypes 2 and 9

Wichgers, P. J., Rebel, J. M. J., Smits, M. A., van Putten, J. P. & Smith, H. E., 2010, In : Veterinary Microbiology. 143, 2-4, p. 363-370

Research output: Contribution to journalArticleAcademicpeer-review

Toll-Like Receptor 6
Streptococcus suis
Toll-Like Receptor 2
lipoproteins
Lipoproteins
10 Citations (Scopus)

Effect of nutrient deficiencies on in vitro Th1 and Th2 cytokine response of peripheral blood mononuclear cells to Plasmodium falciparum infection

Mbugi, E. V., Meijerink, M., Veenemans, J., Jeurink, P. V., McCall, M., Olomi, R. M., Shao, J. F., Chilongola, J., Verhoef, H. & Savelkoul, H. F. J., 2010, In : Malaria Journal. 9, 15 p., 162.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Plasmodium falciparum
Malaria
Blood Cells
Cytokines
Food
158 Citations (Scopus)

Guidance for Substantiating the Evidence for Beneficial Effects of Probiotics: Current Status and Recommendations for Future Research1–3,

Rijkers, G. T., Bengmark, S., Enck, P., Haller, D., Herz, U., Kalliomäki, M., Kudo, S., Lenoi-Winkoop, I., Mercenier, A. M. E., Myllyluoma, E., Rabot, S., Rafter, J., Szajewska, H., Watzl, B., Wells, J., Wolvers, D. & Antoine, J. M., 2010, In : The Journal of Nutrition. 140, 3, p. 671S-676S

Research output: Contribution to journalArticleAcademicpeer-review

Probiotics
Guidelines
Food Industry
Microbiota
Insurance Benefits
112 Citations (Scopus)

Guidance for Substantiating the Evidence for Beneficial Effects of Probiotics: Prevention and Management of Allergic Diseases by Probiotics1–3,

Kalliomäki, M., Antoine, J. M., Herz, U., Rijkers, G. T., Wells, J. & Mercenier, A. M. E., 2010, In : The Journal of Nutrition. 140, 3, p. 713S-721S

Research output: Contribution to journalArticleAcademicpeer-review

Probiotics
Disease Management
Atopic Dermatitis
Hypersensitivity
Hygiene Hypothesis
120 Citations (Scopus)

Identification of Genetic Loci in Lactobacillus plantarum That Modulate the Immune Response of Dendritic Cells Using Comparative Genome Hybridization

Meijerink, M., van Hemert, S., Taverne, N., Wels, M. W. W., Bron, P. A., de Vos, P., Savelkoul, H. F. J., van Bilsen, J. G. P. M., Kleerebeezem, M. & Wells, J., 2010, In : PLoS ONE. 5, 5, 12 p., e10632.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
comparative genomic hybridization
Lactobacillus plantarum
Genetic Loci
Comparative Genomic Hybridization
dendritic cells
114 Citations (Scopus)

Identification of Lactobacillus plantarum genes modulating the cytokine response of human peripheral blood mononuclear cells

van Hemert, S., Meijerink, M., Molenaar, D., Bron, P. A., de Vos, P., Kleerebezem, M., Wells, J. & Marco, M., 2010, In : BMC Microbiology. 10, 293.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Lactobacillus plantarum
Blood Cells
Cytokines
Interleukin-12
Genes
23 Citations (Scopus)

Probiotic modulation of dendritic cells and T cell responses in the intestine

Meijerink, M. & Wells, J., 2010, In : Beneficial Microbes. 1, 4, p. 317-326

Research output: Contribution to journalArticleAcademicpeer-review

Probiotics
Dendritic Cells
Intestines
T-Lymphocytes
Mucous Membrane
266 Citations (Scopus)

Regulation of human epithelial tight junction proteins by Lactobacillus plantarum in vivo and protective effects on the epithelial barrier

Karczewski, J., Troost, F. J., Konings, I., Dekker, J., Kleerebezem, M., Brummer, R. J. & Wells, J., 2010, In : American Journal of Physiology. Gastrointestinal and Liver Physiology. 298, 6, p. G851-G859

Research output: Contribution to journalArticleAcademicpeer-review

Tight Junction Proteins
Lactobacillus plantarum
Tight Junctions
Occludin
Toll-Like Receptor 2
7 Citations (Scopus)

Small intestinal segment perfusion test in piglets: future applications in studying probiotics-gut crosstalk in infectious diarrhoea?

van der Meulen, J., Hulst, M. M., Smits, M. A. & Schuurman, T., 2010, In : Beneficial Microbes. 1, 4, p. 439-445

Research output: Contribution to journalArticleAcademicpeer-review

Probiotics
Enterotoxigenic Escherichia coli
Diarrhea
Perfusion
Rotavirus
59 Citations (Scopus)

The role of innate signaling in the homeostasis of tolerance and immunity in the intestine.

Wells, J., Loonen, L. M. P. & Karczewski, J., 2010, In : International Journal of Medical Microbiology. 300, 1, p. 41-48

Research output: Contribution to journalArticleAcademicpeer-review

Toll-Like Receptors
Intestines
Immunity
Homeostasis
Intestinal Mucosa
15 Citations (Scopus)

Transcriptomics of enterotoxigenic Escherichia coli infection. Individual variation in intestinal gene expression correlates with intestinal function

Niewold, T. A., van der Meulen, J., Kerstens, H. H. D., Smits, M. A. & Hulst, M. M., 2010, In : Veterinary Microbiology. 141, 1-2, p. 110-114

Research output: Contribution to journalArticleAcademicpeer-review

Enterotoxigenic Escherichia coli
Escherichia coli Infections
enterotoxigenic Escherichia coli
transcriptomics
Gene Expression
2009
25 Citations (Scopus)

AI-2 does not function as a quorum sensing molecule in Campylobacter jejuni during exponential growth in vitro

Holmes, K., Tavender, T. J., Winzer, K., Wells, J. & Hardie, K., 2009, In : BMC Microbiology. 9, 12 p., 214.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Quorum Sensing
Campylobacter jejuni
Growth
Eagles
Vibrio cholerae
269 Citations (Scopus)

Differential NF-κB pathways induction by Lactobacillus plantarum in the duodenum of healthy humans correlating with immune tolerance

van Baarlen, P., Troost, F. J., van Hemert, S., van der Meer, C., de Vos, W. M., de Groot, P. J., Hooiveld, G. J. E. J., Brummer, R. J. & Kleerebezem, M., 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 7, p. 2371-2376

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Lactobacillus plantarum
Immune Tolerance
Duodenum
Bacteria
Intestinal Mucosa
25 Citations (Scopus)

Evolutionary relationships between Fusarium oxysporum f. sp. lycopersici and F. oxysporum f. sp. radicis-lycopersici isolates inferred from mating type, elongation factor-1a exopolygalacturonase sequences

Lievens, B., van Baarlen, P., Verreth, C., van Kerckhove, S., Rep, M. & Thomma, B. P. H. J., 2009, In : Mycological Research. 113, 10, p. 1181-1191

Research output: Contribution to journalArticleAcademicpeer-review

Mating Factor
exopolygalacturonase
Fusarium oxysporum f. sp. radicis-lycopersici
Fusarium oxysporum f. sp. lycopersici
Peptide Elongation Factors
2008
56 Citations (Scopus)

Identification of the transcriptional response of human intestinal mucosa to Lactobacillus plantarum WCFS1 in vivo

Troost, F. J., van Baarlen, P., Lindsey, P., Kodde, A., de Vos, W. M., Kleerebezem, M. & Brummer, R. J., 2008, In : BMC Genomics. 9, 14 p., 374.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Lactobacillus plantarum
Intestinal Mucosa
Probiotics
Cell Death
Gastrointestinal Intubation
361 Citations (Scopus)

Mucosal delivery of therapeutic and prophylactic molecules using lactic acis bacteria

Wells, J. & Mercenier, A. M. E., 2008, In : Nature Reviews Microbiology. 6, 5, p. 349-362

Research output: Contribution to journalArticleAcademicpeer-review

Lactic Acid
Milk
Bacteria
Antigens
Lactococcus
2007
77 Citations (Scopus)

Mucosal delivery of a pneumococcal vaccine using lactococcus lactis affords protection against respiratory infection

Hanniffy, S. B., Carter, A. T., Hitchin, E. & Wells, J., 2007, In : The Journal of Infectious Diseases. 195, 2, p. 185-193

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Pneumococcal Vaccines
Lactococcus lactis
Respiratory Tract Infections
Vaccines
Streptococcus pneumoniae
36 Citations (Scopus)

Riboflavin Biosynthesis Is Associated with Assimilatory Ferric Reduction and Iron Acquisition by Campylobacter Jejuni.

Gaskin, D. J. H., Holmes, K., Mulholland, F. & Wells, J., 2007, In : Applied and Environmental Microbiology. 73, 24, p. 7819-7825

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Campylobacter jejuni
Riboflavin
riboflavin
Iron
biosynthesis
12 Citations (Scopus)

The European LABDEL project and its relevance to the prevention and treatment of allergies

Daniel, C., Repa, A., Mercenier, A. M. E., Wiedermann, U. & Wells, J., 2007, In : Allergy. 62, 11, p. 1237-1242

Research output: Contribution to journalArticleAcademicpeer-review

Lactic Acid
Hypersensitivity
Bacteria
Mucosal Administration
Inventions
2006
40 Citations (Scopus)

An anti-HIV microbicide engineered in commensal bacteria: secretion of HIV-1 fusion inhibitors by lactobacilli

Pusch, O., Kalyanaraman, R., Tucker, L. D., Wells, J., Rmanratnam, B. & Boden, D., 2006, In : Aids. 20, 15, p. 1917-1922

Research output: Contribution to journalArticleAcademicpeer-review

HIV Fusion Inhibitors
Lactobacillus
Anti-Infective Agents
HIV-1
HIV