Department of Agrotechnology and Food Sciences

Research Output 1931 2020

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Patent
2019

Enrichment of nucleic acids

Bau, H., Song, J., Liu, C., Mauk, M., van der Oost, J. & Hegge, J. W., 19 Sep 2019, Patent No. WO2019178346, Priority date 14 Mar 2018

Research output: PatentOther research output

Open Access
Nucleic Acids
Antigens
Molecules

Fecal matter for prevention or treatment of autoimmune diseases

Nieuwdorp, M. & de Vos, W. M., 6 Sep 2019, Patent No. WO2019168401, Priority date 20 Jul 2018

Research output: PatentOther research output

Open Access
MicroRNAs
Duodenum
Feces
Bacteriophages
Autoimmune Diseases

Method for extracting salt from a composition comprising organic matter

Sanders, J. P. M. & Meesters, K. P. H., 17 Jan 2019, Patent No. WO2019011976, Priority date 11 Jul 2017

Research output: PatentOther research output

Open Access
organic matter
salts
organic compounds
methodology
fertilizers

Method for producing inositol and inorganic phosphate

Sanders, J. P. M., Boeriu, C. G. & Yilmaz, G., 21 Nov 2019, Patent No. WO2019221602 , Priority date 17 May 2018

Research output: PatentOther research output

Open Access
Phytic Acid
Inositol Phosphates
Phosphates
Chemical analysis
Patents and inventions

Method for the preparation of dried oleosomes

Nikiforidis, K., 27 Jun 2019, Patent No. WO2019121758, Priority date 22 Dec 2017

Research output: PatentOther research output

Open Access
Complex Mixtures
Patents and inventions
Oils
Powders
Drying

Thermostable Cas9 nucleases with reduced off-target activity

van der Oost, J., van Kranenburg, R., Bosma, E. F., Mougiakos, I. & Mohanraju, P., 18 Apr 2019, Patent No. WO2019072596, Priority date 10 Oct 2017

Research output: PatentOther research output

Open Access
Micrococcal Nuclease
Gene Deletion
Geobacillus
Pseudomonas putida
Temperature
2018

Alcohol acetyl transferases for alkyl alkanoate production

Kruis, A. J., Levisson, M., Mars, A. E., Kengen, S. W. M., van der Oost, J., Sanders, J. P. M. & Weusthuis, R. A., 8 Jun 2018, Patent No. WO2018099719, Priority date 1 Dec 2016

Research output: PatentOther research output

Open Access
Transferases
Kluyveromyces
Acetyl Coenzyme A
Alcohols
Peptides

Diterminal oxidation of alkanes

van Nuland, Y. M., Weusthuis, R. A. & Eggink, G., 27 Sep 2018, Patent No. WO2018172331, Priority date 23 Mar 2017

Research output: PatentOther research output

Open Access
Alkanes
Oxidation
Acids
Substrates

Floating biofilm

Janssen, M. G. J. & Wijffels, R. H., 15 Aug 2018, Patent No. EP3360954, Priority date 8 Feb 2017

Research output: PatentOther research output

Open Access
biofilm
microorganisms
photosynthesis
body water
carbon dioxide

Microbial genome editing

van der Oost, J., van Kranenburg, R., Bosma, E. F. & Mougiakos, I., 11 May 2018, Patent No. WO2018083128, Priority date 11 Feb 2016

Research output: PatentOther research output

Open Access
Microbial Genome
Homologous Recombination
Temperature
Plasmids
Microbial Genes

Nanofluidic device, fluidic system and method for performing a test

Hohlbein, J. C. & Mathwig, K., 5 Apr 2018, Patent No. WO2018060263, Priority date 30 Sep 2016

Research output: PatentOther research output

Open Access
laminar flow
fluid flow
hydraulics
fluid
test

Prokaryotic argonaute proteins and uses thereof

van der Oost, J. & Hegge, J. W., 18 Jan 2018, Patent No. WO2018011236, Priority date 7 Dec 2016

Research output: PatentOther research output

Open Access
Argonaute Proteins
Nucleic Acids
Biotechnology
Peptides
Synthetic Biology

Thermostable Cas9 nucleases

van der Oost, J., van Kranenburg, R., Bosma, E. F., Mougiakos, I. & Mohanraju, P., 21 Jun 2018, Patent No. WO2018108339, Priority date 14 Dec 2016

Research output: PatentOther research output

Open Access
Micrococcal Nuclease
Genetic Engineering
Nucleic Acids
Peptides
Polynucleotides

Thermostable Cas9 nucleases

van der Oost, J., van Kranenburg, R., Bosma, E. F., Mougiakos, I. & Mohanraju, P., 21 Jun 2018, Patent No. WO2018109101, Priority date 14 Dec 2016

Research output: PatentOther research output

Open Access
Micrococcal Nuclease
Guide RNA
Polynucleotides
Endonucleases
Plasmids
2017

DNA modification

Vlot, M. & Brouns, S. J. J., 6 Apr 2017, Patent No. WO2017055514, Priority date 30 Sep 2015

Research output: PatentOther research output

Open Access
Nucleic Acids
Patents and inventions
DNA
Genes
Genetic engineering

Feed compositions for preventing and treating inflammatory diseases

Bruggeman, G., Bruininx, E. M. A. M., van den Berg, M., de Vos, P., Sahasrabudhe, N. M., Scheurink, A. J. W., Schols, H. A., Scholte, J. & Tian, L., 19 Jan 2017, Patent No. WO2017009257, Priority date 10 Jul 2015

Research output: PatentOther research output

Open Access
Food
pectin

Food and/or feed compositions for preventing and treating inflammatory diseases

Schols, H. A., de Vos, P., van den Berg, M., Bruggeman, G., Bruininx, E. M. A. M., Sahasrabudhe, N. M., Scholte, J., Tian, L. & Scheurink, A. J. W., 9 Jan 2017, Patent No. WO2017009202, Priority date 10 Jul 2015

Research output: PatentOther research output

Open Access
Food
pectin

Food compositions for managing body weight

Schols, H. A., de Vos, P., van den Berg, M., Bruggeman, G., Bruininx, E. M. A. M., Sahasrabudhe, N. M., Scholte, J., Tian, L. & Scheurink, A. J. W., 19 Jan 2017, Patent No. WO2017009203, Priority date 10 Jul 2015

Research output: PatentOther research output

Open Access
food composition
body fat
body mass index
body weight
lipids

Improved CRISPR-Cas9 genome editing tool

Louwen, R. & van der Oost, J., 14 Sep 2017, Patent No. WO2017155408, Priority date 11 Mar 2016

Research output: PatentOther research output

Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
Guide RNA
Proteins
Gene Editing

Improved CRISPR-Cpf1 genome editing tool 

van der Oost, J., van Baarlen, P. & Louwen, R., 14 Sep 2017, Patent No. WO2017155407, Priority date 11 Mar 2016

Research output: PatentOther research output

Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
Guide RNA
Proteins
Gene Editing

Method and apparatus for disruption of biomass cells

D'Hondt, E., Elst, K., Gunerken, E., Garcia-Conzalez, L., Wijffels, R. H. & Eppink, M. H. M., 1 Sep 2017, Patent No. WO2016012613, Priority date 25 Jul 2014

Research output: PatentOther research output

Open Access
Biomass
Pressurization
Emulsions
Pumps
Pressure relief valves

Methods and means for determining treatment of subjects with exogenous somatotropin  

Smits, N. G. E., Blokland, M. H. & Nielen, M. W. F., 14 Dec 2017, Patent No. US2017354717, Priority date 9 Jun 2016

Research output: PatentOther research output

Open Access
Growth Hormone
Disclosure

Novel bacterial species 

de Vos, W. M. & Belzer, C., 19 Oct 2017, Patent No. WO2017178496, Priority date 11 Apr 2016

Research output: PatentOther research output

Open Access
digestive system
Python
cosmetics
mucus
probiotics

Pectin compositions for preventing and treating inflammatory diseases

Bruggeman, G., Bruininx, E. M. A. M., van den Berg, M., de Vos, P., Sahasrabudhe, N. M., Scheurink, A. J. W., Schols, H. A. & Scholte, J., 19 Jan 2017, Patent No. WO2017009257, Priority date 10 Jul 2015

Research output: PatentOther research output

Open Access
Food
pectin

Pectins improving energy redistribution in animals

Bruggeman, G., Bruininx, E. M. A. M., van den Berg, M., de Vos, P., Sahasrabudhe, N. M., Scheurink, A. J. W., Schols, H. A., Scholte, J. & Tian, L., 19 Jan 2017, Patent No. WO2017009259, Priority date 10 Jul 2015

Research output: PatentOther research output

Open Access
pectins
carbohydrate composition
energy
esterification
animals

Use of pasteurized Akkermansia for treating metabolic disorders

Cani, P., Everard, A., Plovier, H., Druart, C., de Vos, W. M. & Belzer, C., 16 Mar 2017, Patent No. WO2017042347, Priority date 10 Sep 2015

Research output: PatentOther research output

Open Access
Weight Loss
Pharmaceutical Preparations
2016

A method of manufacturing a microfluidic device

Saggiomo, V. & Velders, A. H., 6 Oct 2016, Patent No. WO2016155760, Priority date 27 Mar 2015

Research output: PatentOther research output

Open Access
Microfluidics
Polymers
Liquids
Curing

Bacteria-comprising compositions and methods of using the same for treating and/or preventing gastrointestinal, metabolic and/or other diseases

de Vos, W. M., 14 Jul 2016, Patent No. WO2016110585, Priority date 9 Jan 2015

Research output: PatentOther research output

Open Access
Butyrates
Lysine
Bacteria
Advanced Glycosylation End Products
Probiotics

Biosensor comprising a modified metal surface and method for the modification of a metal surface

Alonso Carnicero, J. M., Franssen, M. C. R., Bielen, A. A. M., Scheres, L. M. W., Schütz-Trilling, A. K., Zeper, W. B., Zuilhof, J. T., van Paassen, P. A. M., Olthuis, W. & Rassaei, L., 4 Feb 2016, Patent No. WO2016018148, Priority date 30 Jul 2014

Research output: PatentOther research output

Open Access
Biosensors
Metals
Patents and inventions
Electrodes
Atoms

Compounds against ralstonia pickettii for use in the treatment of insulin resistance, and method of diagnosis of insulin resistance  

Nieuwdorp, M., de Vos, W. M. & de Pauw, E. S. D., 3 Mar 2016, Patent No. WO2016030500, Priority date 28 Aug 2014

Research output: PatentOther research output

Open Access
Ralstonia pickettii
Insulin Resistance
Nucleic Acids
Antibodies
Type 2 Diabetes Mellitus

Enzymatic activity of lytic polysaccharide monooxygenase

Koetsier, M. J., Visser, J., Hinz, S. W. A., Kabel, M. A., Frommhagen, M. & Gruppen, H., 15 Sep 2016, Patent No. WO2016142536, Priority date 11 Mar 2015

Research output: PatentOther research output

Open Access
xylan
polysaccharides
degradation
hemicellulose
cellulose

Method of culturing Akkermansia

Belzer, C. & de Vos, W. M., 10 Nov 2016, Patent No. WO2016177801, Priority date 5 Jun 2015

Research output: PatentOther research output

Open Access
drugs
biomass
animals
methodology

Nuclease-mediated genome editing

van der Oost, J., 20 Oct 2016, Patent No. WO2016166340, Priority date 16 Apr 2015

Research output: PatentOther research output

Open Access
Nucleic Acids
Peptides
Synthetic Biology
Synthetic Genes
Genetic Techniques

Process for producing itaconic acid under anaerobic conditions

Weusthuis, R. A., Vuoristo, K. S., Eggink, G. & Sanders, J. P. M., 25 Aug 2016, Patent No. WO2016131818, Priority date 16 Feb 2015

Research output: PatentOther research output

Open Access
aconitate decarboxylase
Fermentation
Citric Acid Cycle
Lactic Acid
Acetates

Process for recovering elemental selenium from wastewater

Hageman, S. P. W., van der Weijden, R. D. & Buisman, C. J. N., 21 Jan 2016, Patent No. WO2016010419, Priority date 14 Jul 2014

Research output: PatentOther research output

Open Access
selenium
wastewater
sludge
groundwater

Riboswitch-controlled screening and selection of desired biocatalysts 

Creutzburg, S. C. A. & van der Oost, J., 20 Oct 2016, Patent No. WO2016166303, Priority date 16 Apr 2015

Research output: PatentOther research output

Open Access
Riboswitch
Enzymes
RNA Splicing
Bacterial Genomes
Reading Frames

Riboswitch inducible gene expression

Creutzburg, S. C. A. & van der Oost, J., 20 Oct 2016, Patent No. WO2016166310, Priority date 16 Apr 2015

Research output: PatentOther research output

Open Access
Riboswitch
Gene Expression
Enzymes
Reading Frames
Reporter Genes

System and method for bio-electrochemical water oxidation

Strik, D. P. B. T. B. & Wetser, K., 5 Oct 2016, Patent No. EP3075884, Priority date 31 Mar 2015

Research output: PatentOther research output

Open Access
Oxidation
Electrodes
Water
Patents and inventions
Ions

Thermostable Cas9 nucleases

van der Oost, J., Daas, M. J. A., Kengen, S. W. M. & de Vos, W. M., 15 Dec 2016, Patent No. WO2016198361, Priority date 12 Jun 2015

Research output: PatentOther research output

Open Access
Micrococcal Nuclease
Genetic Engineering
Nucleic Acids
DNA Cleavage
Peptides
2015

Hard and semi-hard cheese comprising water retaining particles, a method for preparing such hard or semi-hard cheese, and the use of such particles in the preparation of cheese

Luyten, J. M. J. G., Koning, A., Faber, T. J., Peters, J. P. C. M. & Paques, J. P., 30 Apr 2015, Patent No. WO2015060715, Priority date 21 Oct 2013

Research output: PatentOther research output

Open Access
Cheeses
Patents and inventions
Water

Method for the single step introduction of a plurality of genes in microbial cells

van der Straat, L. & de Graaff, L. H., 25 Feb 2015, Patent No. EP2840139

Research output: PatentOther research output

Open Access
Microbial Genes
DNA
Enzymes
Genes

Plants with modified vascular tissue

de Rybel, B. P. M. & Weijers, D., 12 Feb 2015, Patent No. WO2015018459, Priority date 9 Aug 2013

Research output: PatentOther research output

Open Access
vascular tissues
plant anatomy
nucleic acids
industrial applications
biofuels

Process for the production of methacrylic acid

Le Nôtre, J., Scott, E. L., Croes, R. L. & van Haveren, J., 5 Mar 2015, Patent No. WO2015030580, Priority date 26 Aug 2013

Research output: PatentOther research output

Open Access
Aconitic Acid
Citric Acid
Isomers
Transition metals
Derivatives

Systematic optimization of coding sequence for functional protein expression

van der Oost, J., 9 Apr 2015, Patent No. WO2015048989, Priority date 2 Oct 2013

Research output: PatentOther research output

Open Access
Codon
Proteins
2014

Anoxic biological production of fuels and of bulk chemicals from second generation feedstocks

de Bont, J. A. M., Raab, A., Schilling, M., Tamame González, M. M., De los Ángeles Santos García, M., Martins dos Santos, V. A. P., Arjona Antolín, R. & Gutiérrez Gómez, P., 31 Dec 2014, Patent No. WO2014207099, Priority date 26 Jun 2013

Research output: PatentOther research output

Open Access
Pentoses
Feedstocks
Fatty Acids
Fermentation
Alkanes

A process for isolating proteins from solid protein-containing biomass selected from vegetable biomass, algae, seaweed and combinations thereof

Zhang, C., Sanders, J. P. M. & Bruins, M. E., 27 Mar 2014, Patent No. WO2014046543, Priority date 21 Sep 2012

Research output: PatentOther research output

Open Access
algae
vegetables
biomass
proteins
extracts

DNA-guided DNA interference by a prokaryotic Argonaute

van der Oost, J. & Swarts, D. C., 27 Nov 2014, Patent No. WO2014189628, Priority date 11 Apr 2013

Research output: PatentOther research output

Open Access
Nucleic Acids
DNA
Amino Acids
Chemical analysis

Energy management system for conversion of solar energy and method of establishing the system in a greenhouse

van Rijn, C. J. M., 7 Jan 2014, Patent No. NL2011096, Priority date 5 Jul 2012

Research output: PatentOther research output

Open Access
Energy management systems
Greenhouses
Solar energy

Fungals strains with improved citric acid and itaconic acid production

van der Straat, L., Schonewille, T., Tamayo Ramos, J. A. & de Graaff, L. H., 18 Sep 2014, Patent No. WO2014142647, Priority date 14 Mar 2013

Research output: PatentOther research output

Open Access
citric acid
acids
cells

Genetically engineered micro-organisms for production of fatty acids

Weusthuis, R. A., van der Oost, J. & Eggink, G., 30 Jan 2014, Patent No. WO2014016328, Priority date 25 Jul 2012

Research output: PatentOther research output

Open Access
fatty acid
micro-organism
method