Overexpression of p21 in NEMOΔhepa animals protects against DNA damage, acceleration of hepatocarcinogenesis and cholestasis. As strengthened by our LPS stimulation experiments, we identified a novel protective role of p21 against DNA damage.
|Date made available||1 Mar 2015|
Ehedego, H. (Creator), Boekschoten, M. (Creator), Hu, W. (Creator), Doler, C. (Creator), Haybaeck, J. (Creator), Gaßler, N. (Creator), Muller, M. (Creator), Liedtke, C. (Creator), Trautwein, C. (Creator)(1 Mar 2015). Loss of p21 expression enhances DNA damage, cholestasis and hepatocarcinogenesis in the liver. Wageningen University.