Research Output per year
To increase our knowledge of the effects of Fructo oligosaccharides (FOS) on the intestinal barrier function in rats, a controlled rat infection study was performed. Two groups of rats (n=12 per group) were adapted to a diet with or without FOS. mRNA was collected from the mucosa of the cecum and changes in gene expression were assessed using an agilent rat whole genome microarray (G4131A Agilent Technologies). Results indicate that dietary FOS influences immune response and wound healing mechanisms, which will most likely affect the intestinal barrier.
|Date made available||31 Dec 2007|
|Publisher||Rikilt - Institute of Food Safety|
A framework to identify physiological responses in microarray based gene expression studies: selection and interpretation of biologically relevant genesRodenburg, G. C. H., Heidema, A. G., Boer, J. M. A., Bovee-Oudenhoven, I. M. J., Feskens, E. J. M., Mariman, E. C. M. & Keijer, J., 2008, In : Physiological genomics. 33, p. 78-90
Research output: Contribution to journal › Article › Academic › peer-review
Rodenburg, G. C. H. (Creator), Kramer, E. (Creator), Bovee-Oudenhoven, I. (Creator), Keijer, J. (Creator) (31 Dec 2007). Gene expression changes in cecum mucosa upon dietary treatment . Rikilt - Institute of Food Safety.