Description
We assessed indels resulting from Cas9-induced genome editing in CML cells in the presence of guide-complementary DNA oligonucleotides intended to inhibit Cas9 activity. We amplified pre-determined loci that were target with the supplied guides or were expected to be off-target sites for these guides. The on-target loci are EMX1 and FANCF.
| Date made available | 13 Jan 2022 |
|---|---|
| Publisher | Wageningen University & Research |
Accession numbers
- PRJNA796802
Research output
- 1 Article
-
Modulating CRISPR-Cas Genome Editing Using Guide-Complementary DNA Oligonucleotides
Swartjes, T., Shang, P., Van Den Berg, D. T. M., Künne, T., Geijsen, N., Brouns, S. J. J., van der Oost, J., Staals, R. H. J. & Notebaart, R. A., 12 Aug 2022, In: CRISPR Journal. 5, 4, p. 571-585Research output: Contribution to journal › Article › Academic › peer-review
Open Access
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