Research output per year
Research output per year
Description
The use of Akkermansia muciniphila as potential therapeutic intervention is receiving increasing attention. Health benefits attributed to this bacterium include an improvement of metabolic disorders and exerting anti-inflammatory effects. The abundance of A. muciniphila is associated with a healthy gut in early mid- and later life. However, the effects of A. muciniphila on a decline in intestinal health during the aging process are not investigated yet. We supplemented accelerated aging Ercc1-/Δ7 mice with A. muciniphila for 10 weeks and investigated histological, transcriptional and immunological aspects of intestinal health.
| Date made available | 5 Mar 2019 |
|---|---|
| Publisher | Wageningen University |
Accession numbers
- PRJNA525606
- SRP187521
Research output
- 1 Article
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Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1 -/Δ7 mice
van der Lugt, B., van Beek, A. A., Aalvink, S., Meijer, B., Sovran, B., Vermeij, W. P., Brandt, R. M. C., de Vos, W. M., Savelkoul, H. F. J., Steegenga, W. T. & Belzer, C., 8 Mar 2019, In: Immunity and Ageing. 16, 1, 6.Research output: Contribution to journal › Article › Academic › peer-review
Open Access112 Citations (Scopus)
Datasets
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Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1-/Δ7 mice
van der Lugt, B. (Creator), Van Beek, A. A. (Creator), Aalvink, S. (Creator), Meijer, B. (Creator), Sovran, B. (Creator), Vermeij, W. P. (Creator), Brandt, R. M. C. (Creator), de Vos, W. (Creator), Savelkoul, H. (Creator), Steegenga, W. T. (Creator) & Belzer, C. (Creator), Wageningen University, 20 Feb 2019
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE126730
Dataset